Optimizing selection for quantitative traits with information on an
... on phenotypic information alone, resulted in greater genetic improvement in the longer term than selection on a combination of phenotypic information and information on identified genes (genotypic selection). Thus, selection criteria that are optimal in the short term may not lead to maximum respons ...
... on phenotypic information alone, resulted in greater genetic improvement in the longer term than selection on a combination of phenotypic information and information on identified genes (genotypic selection). Thus, selection criteria that are optimal in the short term may not lead to maximum respons ...
Click Chemistry in Peptide-Based Drug Design
... Head-to-tail cyclization is an important approach to increase structural rigidity and stability of peptides. Exoproteases such as aminopeptidases or metallo-carboxypeptidases can recognize N- or Cterminal groups and hydrolyze peptides. As a result, head-to-tail cyclopeptides are relatively more resi ...
... Head-to-tail cyclization is an important approach to increase structural rigidity and stability of peptides. Exoproteases such as aminopeptidases or metallo-carboxypeptidases can recognize N- or Cterminal groups and hydrolyze peptides. As a result, head-to-tail cyclopeptides are relatively more resi ...
chromosomal
... interstitial deletion Caused by very small deletion on the long arm of chromosome 7. Deletion include elastin gene which code a protein that gives the blood vessels the stretchiness The lack of the elastin protein, people with Williams syndrome have disorder of circulatory system ...
... interstitial deletion Caused by very small deletion on the long arm of chromosome 7. Deletion include elastin gene which code a protein that gives the blood vessels the stretchiness The lack of the elastin protein, people with Williams syndrome have disorder of circulatory system ...
Amber Extract
... Amber has been credited with numerous beneficial properties both physical and spiritual. The Ancient Romans and Greeks used it to cure ailments such as asthma, rheumatism and internal problems. Its purported healing powers have extended to epilepsy, jaundice, kidney and bladder complaints and even t ...
... Amber has been credited with numerous beneficial properties both physical and spiritual. The Ancient Romans and Greeks used it to cure ailments such as asthma, rheumatism and internal problems. Its purported healing powers have extended to epilepsy, jaundice, kidney and bladder complaints and even t ...
Hypoxia in skeletal muscles: from physiology to gene expression
... dehydrogenase are increased [23, 48, 50]. It is believed that the changes of blood glucose due to the inhibition of oxidative phosphorylation cause the up-regulation of GLUT-mediated glucose transport [51]. Briefly, more GLUTs are translocated to plasma membrane and transporters pre-exiting in the p ...
... dehydrogenase are increased [23, 48, 50]. It is believed that the changes of blood glucose due to the inhibition of oxidative phosphorylation cause the up-regulation of GLUT-mediated glucose transport [51]. Briefly, more GLUTs are translocated to plasma membrane and transporters pre-exiting in the p ...
DANIELE GHEZZI Matr. N°. 708361 Identification and
... but, despite several studies, further cases of paternal transmission have never been described. The dogma of the maternal inheritance of the mtDNA remains true in practice for genetic counselling and for evolutionary studies. Each human cell has thousands of mitochondria and within each single mitoc ...
... but, despite several studies, further cases of paternal transmission have never been described. The dogma of the maternal inheritance of the mtDNA remains true in practice for genetic counselling and for evolutionary studies. Each human cell has thousands of mitochondria and within each single mitoc ...
ABO genotyping in leukemia patients reveals new ABO variant alleles
... sequence, to which other ABO alleles are compared. The ABO*B101 allele is distinguishable from ABO*A101 at eight nucleotide (nt) positions, which result in four amino acid changes in the expressed protein. Among these, substitutions responsible for alterations at two sites (L266M and G268A) determin ...
... sequence, to which other ABO alleles are compared. The ABO*B101 allele is distinguishable from ABO*A101 at eight nucleotide (nt) positions, which result in four amino acid changes in the expressed protein. Among these, substitutions responsible for alterations at two sites (L266M and G268A) determin ...
The Ff.010 Gene Product Regulates the Expression Domain of
... clarity, we will define the fourth whorl of Flol O flowers as including all organs that develop after the six third-whorl stamens. The stamen-carpel intermediate organs at one extreme resemble normal stamens with small sectors of carpel tissue and/or fusion with adjacent organs (Figures 4C and 4D). ...
... clarity, we will define the fourth whorl of Flol O flowers as including all organs that develop after the six third-whorl stamens. The stamen-carpel intermediate organs at one extreme resemble normal stamens with small sectors of carpel tissue and/or fusion with adjacent organs (Figures 4C and 4D). ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable breakpoints on both genes. Abnormal Protein N-term - AT hook and DNA methyltransferase from MLL fused to the 192 C-term amino acids from AF9 (as breakpoints are variable, this is only an example). ...
... May be overlooked; often as a sole anomaly. Hybrid/Mutated Gene Variable breakpoints on both genes. Abnormal Protein N-term - AT hook and DNA methyltransferase from MLL fused to the 192 C-term amino acids from AF9 (as breakpoints are variable, this is only an example). ...
Classification of colorectal cancer based on correlation of clinical
... in MSI-H CRC cell lines37 is probably due to the fact that very few such cell lines are derived from sporadic MSI-H CRCs. Methylation of the APC promoter could fill the mutational gap in theory, but this epigenetic change occurs in only 18% of CRCs, may affect the wild-type allele when there is alre ...
... in MSI-H CRC cell lines37 is probably due to the fact that very few such cell lines are derived from sporadic MSI-H CRCs. Methylation of the APC promoter could fill the mutational gap in theory, but this epigenetic change occurs in only 18% of CRCs, may affect the wild-type allele when there is alre ...
LIST OF CHECK-UP QUESTIONS for
... Answers multiple tests, choose and indicate the correct answer/statement, please: 1. The non-membranous organelles are: a) ribosomes; CORRECT b) Golgi body; c) lysosomes; d) Endoplasmic reticulum; e) nucleus 2. Chloroplasts and mitochondria both NOT: a) are found in plant cells; b) have two membrane ...
... Answers multiple tests, choose and indicate the correct answer/statement, please: 1. The non-membranous organelles are: a) ribosomes; CORRECT b) Golgi body; c) lysosomes; d) Endoplasmic reticulum; e) nucleus 2. Chloroplasts and mitochondria both NOT: a) are found in plant cells; b) have two membrane ...
Do-it-yourself poster template - College of Education and Human
... pGEM-T easy vector as well as a plant expression referred to as the pSAT vector. For future research once all genes have been sub-cloned into the pSAT vector they will then be used to transform carrot calli. The transgenic plants will then coexpress the gene products in the carrot plants. ...
... pGEM-T easy vector as well as a plant expression referred to as the pSAT vector. For future research once all genes have been sub-cloned into the pSAT vector they will then be used to transform carrot calli. The transgenic plants will then coexpress the gene products in the carrot plants. ...
here - Glaucoma Genetics Lab
... members of this pedigree with POAG had a mean maximum IOP of 22.5 mm Hg, but six (43%) of these family members had never had an IOP recorded above 21 mm Hg. While members of this glaucoma pedigree together have average ages at diagnosis and average maximum IOPs typical for a diagnosis of POAG, some ...
... members of this pedigree with POAG had a mean maximum IOP of 22.5 mm Hg, but six (43%) of these family members had never had an IOP recorded above 21 mm Hg. While members of this glaucoma pedigree together have average ages at diagnosis and average maximum IOPs typical for a diagnosis of POAG, some ...
Allele and Genotype Frequencies of the ABO Blood Group System in
... distributed over 18 kb of genomic DNA, ranging in size from 28 to 688 base pairs (bp) and 6 introns with 554 to 12982 bp (6-8) (Figure 1.1). Exon 7 contains most of the largest coding sequence whereas, exon 6 contains the deletion found in most O alleles ...
... distributed over 18 kb of genomic DNA, ranging in size from 28 to 688 base pairs (bp) and 6 introns with 554 to 12982 bp (6-8) (Figure 1.1). Exon 7 contains most of the largest coding sequence whereas, exon 6 contains the deletion found in most O alleles ...
Control of Fatty-Acid Biosynthesis by Long
... with the lipid added (not shown). Curve 111: acetylCoA carboxylase was replaced by its product malonylCoA while the other conditions were identical to those of the experiment of curve 11. The main difference to the experiment of curve I1 is the about four-fold increase of long-chain acyl-CoA formati ...
... with the lipid added (not shown). Curve 111: acetylCoA carboxylase was replaced by its product malonylCoA while the other conditions were identical to those of the experiment of curve 11. The main difference to the experiment of curve I1 is the about four-fold increase of long-chain acyl-CoA formati ...
Leukaemia Section Classification of acute myeloid leukemias Atlas of Genetics and Cytogenetics
... changes have enabled the cloning of genes located at chromosomal breakpoints and have helped to characterize the proteins involved in leukemogenesis. Morphologic studies remain important because of a strong correlation with cytogenetic and molecular abnormalities. The clinico-biological classificati ...
... changes have enabled the cloning of genes located at chromosomal breakpoints and have helped to characterize the proteins involved in leukemogenesis. Morphologic studies remain important because of a strong correlation with cytogenetic and molecular abnormalities. The clinico-biological classificati ...
glycogen metabolism
... chain already contains more than four residues. • Thus, glycogen synthesis requires a primer. – This priming function is carried out by glycogenin, a protein composed of two identical 37-kd subunits, each bearing an oligosaccharide of a-1,4-glucose units. – C1 of the first unit of this chain, the re ...
... chain already contains more than four residues. • Thus, glycogen synthesis requires a primer. – This priming function is carried out by glycogenin, a protein composed of two identical 37-kd subunits, each bearing an oligosaccharide of a-1,4-glucose units. – C1 of the first unit of this chain, the re ...
Vitamin C
... • Vitamin C acts as an electron donor for 8 different enzymes: • Three enzymes participate in collagen hydroxylation. • Two enzymes are necessary for synthesis of carnitine. • Three remaining enzymes have the following functions in common, but have other functions as well: • Dopamine β-hydroxylase p ...
... • Vitamin C acts as an electron donor for 8 different enzymes: • Three enzymes participate in collagen hydroxylation. • Two enzymes are necessary for synthesis of carnitine. • Three remaining enzymes have the following functions in common, but have other functions as well: • Dopamine β-hydroxylase p ...
Human pigmentation variation: Evolution, genetic basis, and
... genes involved in normal pigmentation variation in human populations. At least six genes have been identified using genotype/phenotype association studies and/or direct functional assays, and there is evidence indicating that several additional genes may be playing a role in skin, hair, and iris pig ...
... genes involved in normal pigmentation variation in human populations. At least six genes have been identified using genotype/phenotype association studies and/or direct functional assays, and there is evidence indicating that several additional genes may be playing a role in skin, hair, and iris pig ...
Intrinsically Disordered Protein - Center for Data Analytics and
... paradigm: In 1950, Karush19 reported that, unlike essentially every other native protein known at the time, serum albumin exhibited a nearly universal capacity for the high-affinity binding of small, hydrophobic, typically anionic molecules. Competitive binding was demonstrated for molecules of very ...
... paradigm: In 1950, Karush19 reported that, unlike essentially every other native protein known at the time, serum albumin exhibited a nearly universal capacity for the high-affinity binding of small, hydrophobic, typically anionic molecules. Competitive binding was demonstrated for molecules of very ...
PCNA Protein Expression during Spermatogenesis of the
... and rat recombinant PCNA proteins (see “Characterization of two PCNA proteins”) and also because they were not detected in a negative control without the primary antibody (data not shown), we concluded that these bands were the eel PCNA. In eel spermatogenesis, proliferation of spermatogonia, meiosi ...
... and rat recombinant PCNA proteins (see “Characterization of two PCNA proteins”) and also because they were not detected in a negative control without the primary antibody (data not shown), we concluded that these bands were the eel PCNA. In eel spermatogenesis, proliferation of spermatogonia, meiosi ...
The pleiotropic structure of the genotype–phenotype
... rather than by removing or creating an entire gene. Mutational pleiotropy tends to be smaller than gene plei‑ otropy (for examples, see REF. 25). nevertheless, one can argue that the pleiotropy of knockout genotypes gives an upper limit of mutational pleiotropy, as it is plausible that a complete lo ...
... rather than by removing or creating an entire gene. Mutational pleiotropy tends to be smaller than gene plei‑ otropy (for examples, see REF. 25). nevertheless, one can argue that the pleiotropy of knockout genotypes gives an upper limit of mutational pleiotropy, as it is plausible that a complete lo ...
Bartonella chomelii sp. nov., isolated from French domestic cattle
... parasites of red blood cells and endothelial cells. In reservoir hosts, Bartonella infections usually result in asymptomatic bacteraemia. This bacteraemic phase is required for the long-term perpetuation of the bacterium, allowing its transmission by blood-sucking arthropods (Breitschwerdt & Kordick ...
... parasites of red blood cells and endothelial cells. In reservoir hosts, Bartonella infections usually result in asymptomatic bacteraemia. This bacteraemic phase is required for the long-term perpetuation of the bacterium, allowing its transmission by blood-sucking arthropods (Breitschwerdt & Kordick ...