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Wisconsin`s White Deer: Separating Science and Myth by MaLenna
Wisconsin`s White Deer: Separating Science and Myth by MaLenna

Ensembl variation resources Open Access Database
Ensembl variation resources Open Access Database

... organisms (D. melanogaster, C. elegans, S. cerevisiae) are included to facilitate comparative analysis. More comparative analysis is available using species supported by Ensembl Genomes project, a sister project extending Ensembl analysis across a larger taxonomic space [18]. Ensembl is updated appr ...
Syntabulin, a motor protein linker, controls dorsal
Syntabulin, a motor protein linker, controls dorsal

... displays ventralization (Mei et al., 2009). Furthermore, a ubiquitin ligase, tripartite motif-containing 36 (trim36), is localized to the vegetal cortex of Xenopus oocytes, and when depleted causes defective vegetal microtubule array formation and ventralization (Cuykendall and Houston, 2009). Cumul ...
Construction of a linkage map based on a Lathyrus sativus
Construction of a linkage map based on a Lathyrus sativus

... min, followed by 35 cycles of 94C for 15 s, annealing at 40C for 40 s and elongation at 72C for 1 min. The final extension step was held at 72C for 5 min. For STMS analysis, the PCR reaction mixture was identical to the RAPD method, except that 0.4 lM of both the forward and reverse primers were ...
Gene Section MYB (v-myb myeloblastosis viral oncogene homolog (avian))
Gene Section MYB (v-myb myeloblastosis viral oncogene homolog (avian))

Inference of natural selection on quantitative traits
Inference of natural selection on quantitative traits

... using stochastic differential equations and the steady state of a population, balancing the forces of selection (increasing the fitness) and random genetic drift (decreasing the fitness), can be determined using methods of statistical mechanics. In this thesis, I combine aspects of both fields to st ...
Read here - Protect the White Deer
Read here - Protect the White Deer

... The term "mutation" is also misleading, since white deer are not freaks of nature, but the result of genes that prevent them from producing the pigment melanin. They are typically normal in every other way. In fact, the word "mutation" in genetics can refer to any change from a normal type, as this ...
An introduction to informatics - Swiss
An introduction to informatics - Swiss

... exactly the same protein of two or more individuals representing the same species. In other words, I would like to know, if each protein of a given species is represented by exactly one amino acids sequence. If there are some proteins of a given species which are represented by more than one amino a ...
Cell_Cycle_Module_Answers
Cell_Cycle_Module_Answers

... Cdc25 (on residues distinct from the MPF phosphorylation site), resulting in activation of Wee1 and inhibition of Cdc25. a. Adjust parameters to represent the effect of unreplicated DNA on the mitotic control system. Describe the simulation of MPF vs. time. V25” = V25’ = 0.017, Vwee” = 5 (or larger) ...
Gekko 4_1 July 29
Gekko 4_1 July 29

... between the tyrosinase positive albinism in leopard geckos, for example, and several human and murine forms of oculocutaneous albinism, an assortment of disorders that result in reduced or no melanin production. Oculocutaneous albinism 1 (OCA1) is caused by mutations of the tyrosinase gene. One vari ...
Basic Mendellian Genetic
Basic Mendellian Genetic

... 1. After reading the problem, try to give symbols to the alleles, if this isn't already done for you. Often, when describing a condition, a problem will tell you that an allele has a certain symbol. For example, premature balding is dominant over normal head of hair. Premature balding = B and normal ...
Connection of Propionyl-CoA Metabolism to Polyketide
Connection of Propionyl-CoA Metabolism to Polyketide

... which had been prepared as per the manufacturer’s instructions and equilibrated with 5 ml acidified water (0.1% TFA). Retained proteins were washed with 5 ml acidified water (0.1% TFA) and eluted with 1.6 ml of a 50% acetonitrile/0.1% TFA solution. The eluate was divided into two aliquots and concen ...
Supplementary Figure Legends (doc 34K)
Supplementary Figure Legends (doc 34K)

... harbour a complete or partial deletion of the NF1 locus as confirmed by real-time PCR-based gene dosage. Custom high resolution array-CGH enables the accurate characterization of the deletion type. NF1 complete and large partial deletions were observed in 4.2% and 0.5% of NF1 patients in the French ...
Reaction RXN-8964 (implausible prediction)
Reaction RXN-8964 (implausible prediction)

... “Implausible predictions” are not necessarily incorrect, as the genes involved might have several functions, of which only one is visible in sequence similarity-based or domain-based searches. Furthermore, they can include candidate genes that, even if they visibly do not correspond to the proposed ...
of Gray Alpacas - North Sound Alpaca Association
of Gray Alpacas - North Sound Alpaca Association

... For dominant traits, if you have the allele, you have the trait. Clearly, this is not the case for dark-headed roans. Breeding two dark-headed roans together should always yield more darkheaded roans (if it is a simple recessive trait). So far, I have seen no outcomes from such a breeding, but a num ...
Molecular Genetics of Bipolar Disorder and Related Traits
Molecular Genetics of Bipolar Disorder and Related Traits

... understanding of genes and their role in the etiology of disease has substantially increased, especially now that the draft sequence of the human genome is available (7, 8). The human genome consists of 46 chromosomes; 22 pairs of autosomal chromosomes and 2 sex chromosomes. These are built up of ~3 ...
MRSA - Infectious Diseases
MRSA - Infectious Diseases

... promoter regions, resulting in constitutive expression of mecA ...
Defining the Schistosoma haematobium kinome enables the
Defining the Schistosoma haematobium kinome enables the

... Figs 1–11), consistent with their classification using an approach based on hidden Markov models (HMMs). Seven kinase sequences were excluded from phylogenetic analysis, because the catalytic domain of one or both representatives of the orthologous pair did not match the trematode-specific HMM. Six ...
E. Coli MurG: A Paradigm for a Superfamily of
E. Coli MurG: A Paradigm for a Superfamily of

... repeating β-linked disaccharide unit held together by peptide crosslinks (Fig. (1)) [2]. One of the sugars in the repeating disaccharide, N-acetyl muramic acid, is not made in eukaryotic cells. Furthermore, the peptides in the crosslinks contain both D-amino acids and unusual backbone linkages, two ...
projects - Computer Science and Engineering
projects - Computer Science and Engineering

... Vineet Bafna ...
A single gene encodes two differentially targeted
A single gene encodes two differentially targeted

R Is for Arginine Metabolism of Arginine Takes off Again, in New
R Is for Arginine Metabolism of Arginine Takes off Again, in New

... levels might be good for you. This hypothesis appears to be largely correct; however, in 1 clinical study with somewhat contrary findings,10 low plasma homoarginine levels have been found to be associated with increased morbidity or mortality in patients with coronary artery disease, cerebrovascular ...
R Is for Arginine
R Is for Arginine

... levels might be good for you. This hypothesis appears to be largely correct; however, in 1 clinical study with somewhat contrary findings,10 low plasma homoarginine levels have been found to be associated with increased morbidity or mortality in patients with coronary artery disease, cerebrovascular ...
Mutations to nonsense codons in human genetic
Mutations to nonsense codons in human genetic

Characterization of the Sucrose Phosphate Phosphatase (SPP
Characterization of the Sucrose Phosphate Phosphatase (SPP

... or rosette leaves, respectively. cDNA fragments were amplified by PCR using specific primers (Table 1) which were designed with the appropriate restriction sites and a start codon (Met). Next, they were cloned into the pGEM-T Easy vector and finally, in the desired expression vector, which incorpora ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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