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Fulltext - Jultika
Fulltext - Jultika

Does RAGE protect smokers from COPD? CORRESPONDENCE
Does RAGE protect smokers from COPD? CORRESPONDENCE

... results of recent genetic epidemiological studies that suggest the advanced glycosylation end product-specific receptor (AGER) gene, which encodes sRAGE, may also have a role in the development of COPD. Two recent large genome-wide association (GWA) studies conclude that a locus on chromosome 6p21 i ...
Tissue-specific expression of AUX1 in maize roots
Tissue-specific expression of AUX1 in maize roots

... Isolation and characterisation of an AUX1 homologous cDNA from maize For the isolation of a maize AUX1 cDNA, a maize cDNA library was screened with a 300-bp fragment corresponding to a rice EST (D41862) with 74 % sequence identity to the 3′-end of the coding region of the Arabidopsis AUX1 cDNA. Scre ...
An organism containing a normal chromosome complement and
An organism containing a normal chromosome complement and

... Other aneuploids (i.e. primary trisomics, tetrasomics, multiple trisomics, secondary trisomics, tertiary trisomics, compensating trisomics) ...
Document
Document

... • Where is the SNP mapped? Exon, promoter, UTR, etc  picture of gene with mapped to the gene structure. • How was it discovered? Method • What assurances do you have that it is real? Validated how? • What population – African, European, etc? • What is the allele frequency of each SNP? Common (>10%) ...
Mixed modelling to characterize genotype-phenotype
Mixed modelling to characterize genotype-phenotype

... dramatically has been demonstrated [22]. Combining dimension reduction techniques and permutation testing is described for microarray data [24] and HIV genetics data [25]. The former utilizes a permutation test procedure to test for association while the latter is based on a condence band for a nor ...
1 - bioRxiv
1 - bioRxiv

... in females. Almost 80% of all patients with autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, autoimmune thyroid diseases, amongst many others, are women 31-32. Many factors have been proposed to explain this sex bias, including differences in sex hormones, pregnancy ...
Experimental matings: Df/wt x wt
Experimental matings: Df/wt x wt

... in scientific content, skills in experimental design and quantitative literacy, and skills in collaboration and communication (pg 2, NRC 2002). Laboratory explorations on previously unexplored and engaging topics are appropriate venues to develop these skills in an integrative, discovery-based appro ...
New lysosomal acid lipase gene mutants explain the phenotype of
New lysosomal acid lipase gene mutants explain the phenotype of

... obtained due to a Taq error. As this artificial substitution occurs in a position of the acceptor 39 splice site that must be maintained unaltered for correct mRNA processing, it was further analyzed as a control. The LAL WD clone with G➝A substitution at position 11 of the donor site of exon 8 was ...
Cyanogen bromide
Cyanogen bromide

... monomers of β-D-galactopyranose and 3,6-anhydro-α-L-galactopyranose). Cyanogen bromide activation is one of the most common methods for preparing affinity gels, and is useful because it reacts with the hydroxyl groups on agarose to form cyanate esters and imidocarbonates, which are attacked by prima ...
mbe.oxfordjournals.org - Oxford Academic
mbe.oxfordjournals.org - Oxford Academic

... that some nucleolar components involved in ribosome biogenesis rapidly shuttle between the nucleolus and the nucleoplasm (Chen and Huang 2001). Ribosomes are complexes essential for cell proliferation and cell growth present in all organisms (Mayer and Grummt 2006; Bernstein et al. 2007). In bacteri ...
Journal of Genomics The Sex Chromosomes of Frogs: Variability
Journal of Genomics The Sex Chromosomes of Frogs: Variability

... Sex chromosomes differ in the number of copies in a population (Y or W = ¼ the effective population size of autosomes) and therefore have different population genetic dynamics than autosomes. One result of this difference is a divergence in sex chromosome morphology and elimination of recombination: ...
H - Cloudfront.net
H - Cloudfront.net

... example for each word. 6. What is the genotypes of an organism? Give an example. 7. What is the phenotype of an organism? Give an example. 8. Explain the word probability, what does this mean to you? 9. What does a Punnett square show about an organism? 10. How are dominant and recessive alleles rep ...
Document
Document

... Free DNA ...
Plasma membrane
Plasma membrane

... • Cell Theory • Developed from Robert Hooke’s research • Cells are the building blocks of all plants and animals • All cells come from the division of preexisting cells • Cells are the smallest units that perform all vital physiological functions • Each cell maintains homeostasis at the cellular lev ...
Transcriptome and metabolite profiling the infection cycle of
Transcriptome and metabolite profiling the infection cycle of

Genetic Basis for Osmosensitivity and Genetic Instability of the Wine
Genetic Basis for Osmosensitivity and Genetic Instability of the Wine

A1071 GM Canola MON88302 AppR SD1
A1071 GM Canola MON88302 AppR SD1

... Tolerance to glyphosate is achieved through expression of the enzyme 5-enolpyruvyl-3shikimatephosphate synthase (CP4 EPSPS) encoded by the cp4epsps gene derived from the common soil bacterium Agrobacterium sp. The CP4 EPSPS protein has previously been assessed by FSANZ in a range of crops including ...
A Novel Splicing Mutation of KIT Results in Piebaldism and Auburn
A Novel Splicing Mutation of KIT Results in Piebaldism and Auburn

Cotranscriptional coupling of splicing factor recruitment and
Cotranscriptional coupling of splicing factor recruitment and

Intelligent Systems and Bioinformatics Laboratory
Intelligent Systems and Bioinformatics Laboratory

... Note: In order to successfully run the applet, please make sure that proper java plug-in is installed in the browser. For more information on requirements for Onto-Tools click here. ...
Developmental and Genetic Diseases
Developmental and Genetic Diseases

... • Aplasia is the persistence of an organ anlage or rudiment, without the mature organ. Thus, in aplasia of the lung the main bronchus ends blindly in nondescript tissue composed of rudimentary ducts and connective tissue. • Hypoplasia means reduced size owing to incomplete development of all or part ...
Evolution of the chromosomal location of rDNA genes in
Evolution of the chromosomal location of rDNA genes in

... strong in D. sechellia and weak in D. simulans, whereas the reverse is observed for the Y hybridization sites (boxes in Figure 1a and b). In D. mauritiana, the heterochromatic structure of the Y chromosome differs greatly from that observed in D. sechellia and D. simulans (Figure 2a). The Py12 probe ...
Etiology : cytogenetics and microdeletions - HAL
Etiology : cytogenetics and microdeletions - HAL

... 1998]. Subsequently, several genes were isolated from these critical HPE regions, leading to a new nomenclature. The HPE loci previously identified as HPE2, 3, 4, 5, 7 and 9 (OMIM) are now named by their corresponding genes: SIX3, SHH, TGIF, ZIC2, PTCH1 and GLI2, respectively. In addition, there are ...
The Acquisition of Student Nurses` Knowledge of Genetics
The Acquisition of Student Nurses` Knowledge of Genetics

... Genome Research Institute developed the National Coalition for Health Professionals Education in Genetics (NCHPEG) to help incorporate genetics and genomics into healthcare by providing resources to healthcare professionals and students (NCHPEG, 2014). Lashley (2001) described many of these organiza ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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