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Pea Taste Slides - Evo-Ed
Pea Taste Slides - Evo-Ed

... Pea Plants: Mendel to Molecules • Gregor Mendel identified heritable units as the mechanism for traits passing from parents to offspring in pea plants. • These heritable units, called alleles, are versions of specific genes that code for proteins – in this case the SBE1 protein (enzyme). ...
Population genetics by Knud Christensen
Population genetics by Knud Christensen

... two Mendelian segregating gene pairs control the milk yield. For each A or B allele an individual has a yield increase of one kilogram. The alleles A and a have the same frequency in the distributions. For a realistic picture of the genetic background for milk yields, hundreds of gene pairs have to ...
A chitin-binding domain in a marine bacterial
A chitin-binding domain in a marine bacterial

... DNA hybridizations were performed at 65 "C as recommended in the Genus kit manual. The probe was prepared by PCR following the procedure of Lion & Haas (1990), except 10 x DIG DNA labelling mixture (Boehringer Mannheim) was substituted for the nucleotides. PCR was performed with an annealing tempera ...
Negative regulation of defense responses in Arabidopsis by two
Negative regulation of defense responses in Arabidopsis by two

Chance and Necessity in the Selection of Nucleic Acid Catalysts
Chance and Necessity in the Selection of Nucleic Acid Catalysts

... the coin lands heads up. The chance of this happening is approximately 1 in 1030, a sequence of events so rare that one might argue that it could only happen in such a delightful fiction. Similarly rare events, however, may underlie the origins of biological catalysis. What is the probability that a ...
Algorithms for Finding Gene Clusters
Algorithms for Finding Gene Clusters

... set of common intervals to a smaller, generating subset. To apply common intervals to the bioinformatic problem of finding conserved clusters of genes in data derived from completely sequenced genomes we further extended the above algorithm to additional types of permutations. Genomes of higher orga ...
Polydactyl Maine Coons
Polydactyl Maine Coons

... standard, that rather than divide the ranks, a special classification with its own standard was set up for cats possessing the trait.” Some authors estimate the percentage of polydactyls in the breed to be originally as high as 40%. In an interview in 1976 (not long after the Maine Coon was first ac ...
Amino Acids, Peptides, and Proteins
Amino Acids, Peptides, and Proteins

... amino acids are often toxic to other living organisms. With these few minor exceptions all of the naturally occurring amino acids are in the L-form. Calculation of Amino Acid Isoelectric Point For the nonpolar and polar amino acids with two pKa’s, the isoelectric point is calculated by taking the nu ...
Encyclopedia of Nanotechnology
Encyclopedia of Nanotechnology

... In the ray optics regime, in which the dimensions of the trapped particle are larger than the wavelength of the laser light, known as the Mie regime, the origin of optical forces can be understood easily. Figure 1 shows the principle of optical trapping in the Mie regime. In Fig. 1a, a dielectric se ...
Familial Adenomatous Polyposis (FAP)
Familial Adenomatous Polyposis (FAP)

Genetics of dementia (405)
Genetics of dementia (405)

... In contrast, the second type of differences that can occur in genes are rare and are called ‘mutations’. The effect of a mutation tends to be greater and can be harmful – a gene with a mutation is a faulty gene. Sometimes a particular characteristic can be traced back to a mutation in a single gene. ...
Genome-Wide Dissection of Hybrid Sterility in
Genome-Wide Dissection of Hybrid Sterility in

Aberrant DNA methylation in cancer: potential clinical
Aberrant DNA methylation in cancer: potential clinical

... Alterations in DNA methylation might be pivotal in the development of most cancers. In recent years, it has become apparent that the pattern of DNA methylation observed in cancer generally shows a dramatic shift compared with that of normal tissue. Although cancers often exhibit clear reductions thr ...
Genetics of Skin Colour
Genetics of Skin Colour

... the genetic material in skin cells and induce skin cancer. Because most sun induced skin cancers develop well past the reproductive age in people older than 50 years, skin cancer and protection from sunburn are unlikely to have been significant evolutionary factors for the natural selection of ances ...
NCEA Level 1 Science (90948) 2014
NCEA Level 1 Science (90948) 2014

... If a dominant allele was present, then individual 5 would be a tongue roller. So therefore they must have only both recessive alleles present. Individual 6 is a tongue roller, and so must have at least one dominant allele present for tongue rolling to be expressed. Both of 6’s children are a nontong ...
Chap01, Chapter 1: The Molecular Logic of Life
Chap01, Chapter 1: The Molecular Logic of Life

... What six characteristics distinguish living organisms from inanimate objects? Ans: Living organisms (1) are chemically complex and highly organized; (2) extract, transform, and use energy from their environment; (3) have the capacity to precisely self-replicate and self-assemble; (4) exploit a chemi ...
Toxin-Resistant Sodium Channels: Parallel Adaptive Evolution
Toxin-Resistant Sodium Channels: Parallel Adaptive Evolution

... *Sections of Integrative Biology and Neurobiology and Center for Computational Biology, School of Biological Sciences, University of Texas at Austin; and !Department of Medicine, Division of Biological Sciences, University of Chicago Approximately 75% of vertebrate proteins belong to protein familie ...
The Drosophila serum response factor homolog is required for formation of intervein tissue of the wing and is allelic to blistered. Development 122, 2589-2597. pdf
The Drosophila serum response factor homolog is required for formation of intervein tissue of the wing and is allelic to blistered. Development 122, 2589-2597. pdf

... untranslated region of the DSRF transcription unit; pruned1 behaves as a genetic null allele for the tracheal function (Guillemin et al., 1996). All blistered alleles were kindly provided by D. Fristrom (Fristrom et al., 1994 and unpublished results). Homozygous lethal excision alleles from a P-elem ...
Dissecting the protein–RNA interface
Dissecting the protein–RNA interface

... Data set As of 11 November 2010, the PDB listed 824 structures of protein–RNA complexes that had been solved using X-ray crystallography (5). From this data set, 344 complexes were selected based on the following criteria: (i) structural resolution better than 3.0 Å and (ii) polypeptides and polyri ...
NCEA Level 1 Science (90948) 2014 Assessment Schedule
NCEA Level 1 Science (90948) 2014 Assessment Schedule

... If a dominant allele was present, then individual 5 would be a tongue roller. So therefore they must have only both recessive alleles present. Individual 6 is a tongue roller, and so must have at least one dominant allele present for tongue rolling to be expressed. Both of 6’s children are a nontong ...
RNA Structure and the Versatility of RNA
RNA Structure and the Versatility of RNA

... acid sequence of proteins. It does this by carrying an amino acid to the protein synthetic machinery of a cell (ribosome) as directed by a three-nucleotide sequence (codon) in a messenger RNA (mRNA). As such, tRNAs are a necessary component of translation, the biological synthesis of new proteins ac ...
ABSTRACT Using a bioinformatics approach to identify genes that
ABSTRACT Using a bioinformatics approach to identify genes that

Re-sequencing and genotyping the VRN-H, PPD-H, FR
Re-sequencing and genotyping the VRN-H, PPD-H, FR

... (Additional File 1). While the dominant allele was conserved and had just one haplotype, six promoter haplotypes led to the recessive allele (Additional File 4). Eighty-one accessions, including one with winter growth habit, had the CCT domain (loss of function, recessive) mutation in PPD-H1 [26] an ...
Post-transcriptional control of c-erb B-2 overexpression
Post-transcriptional control of c-erb B-2 overexpression

Massive Changes in Genome Architecture Accompany
Massive Changes in Genome Architecture Accompany

... ABSTRACT A large region of suppressed recombination surrounds the sex-determining locus of the self-fertile fungus Neurospora tetrasperma. This region encompasses nearly one-fifth of the N. tetrasperma genome and suppression of recombination is necessary for self-fertility. The similarity of the N. t ...
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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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