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Insulin - Лекарства - билки, фармация
Insulin - Лекарства - билки, фармация

... glutamic acid. Chemically, it is 3B-lysine-29B-glutamic acid-human insulin, has the empirical formula C258H384N64O78S6 and a molecular weight of 5823. It has the following structural formula: ...
Fatty Acid Metabolism - chem.uwec.edu
Fatty Acid Metabolism - chem.uwec.edu

... transferring the CoASH from succinyl–CoA. It is then split into two Acetyl–CoA by a thiolase reaction ...
Nucleic Acids - Farmasi Unand
Nucleic Acids - Farmasi Unand

... • However, other groups in the structures may also contribute to the binding of a drug to the DNA. • For example, the amino group of the sugar residue of doxorubicin forms an ionic bond with the negatively charged oxygens of the phosphate groups of the DNA chain, which effectively locks the drug in ...
Genetic Basis of the Variegated Tail Pattern in the Guppy, Poecilia
Genetic Basis of the Variegated Tail Pattern in the Guppy, Poecilia

... Inheritance of the variegated tail pattern was elucidated by singlepair reciprocal crosses between the GV strain and WT stock, using six-week old mature virgin fish. Each pair was kept in a 3.5-liter breeding tank. Broods were produced 4-6 weeks after mating. Single-pair full-sib F1 males and F1 fem ...
Technical Targets
Technical Targets

... (hyp2) was found within the uptake hydrogenase operon. This raises the question as to which set of maturation genes is responsible for building an active CBS hydrogenase and needs to be co-transformed along with the CBS hydrogenase into Synechocystis. Using qRT-PCR to probe gene expression, we found ...
video slide - Dublin City Schools Home
video slide - Dublin City Schools Home

... A Closer Look: Obtaining the Gene of Interest • How can a researcher obtain DNA that encodes a particular gene of interest? • The “shotgun” approach is one way to synthesize a gene of interest. – Millions of recombinant plasmids containing different segments of foreign DNA are produced. – This coll ...
Novel Multiprotein Complexes Identified in the Hyperthermophilic
Novel Multiprotein Complexes Identified in the Hyperthermophilic

... false positives (16). The epitope tag affinity purification and tandem affinity purification methods have also been used extensively (17–21), but the tags can disrupt native proteinprotein interactions, and the methods tend to be biased toward proteins that interact with high affinity and/or protein ...
310 - aaabg
310 - aaabg

... Sub-vital performance is a phenotype in which some pure white Swakara sheep die within 48 hours of birth. Postmortem of sub-vital lambs have shown underdeveloped digestive organs. It is hypothesized that due to high levels of inbreeding, Swakara sheep carry a recessive mutation that affects some of ...
Topic: Exchange and functions of carbohydrates
Topic: Exchange and functions of carbohydrates

... 3. Defensive barrier (molecules of fat (lipids) with fumes). It is filled with water; it is situated on the external part of epithelial cell. If in normal condition, spirit and water may pass this barrier. This barrier may be destroyed only by detergents. The natural detergents in the organism are ...
Intelligent Icons: Integrating Lite-Weight Data Mining
Intelligent Icons: Integrating Lite-Weight Data Mining

... The three files in the example are ASCII text files, each of which contains approximately 16,000 base pairs of mitochondrial DNA. Here we used string edit distance as suggested in [15] to measure the distance between file names, and Euclidean distance to measure the distance between the file icons ( ...
Allele Frequency Lab
Allele Frequency Lab

...  To see how natural selection acts on the phenotype rather than the genotype of an organism.  To discover that alleles that are lethal in a homozygous individual may be carried in a heterozygous and thus maintained in a gene pool.  To determine that variation within a species increases the likeli ...
Balancer Chromosomes – An Optional Minitutorial What follows is a
Balancer Chromosomes – An Optional Minitutorial What follows is a

... can be used to maintain deleterious mutations in living stocks. You are not required to know these details, but its neat to know some of the cool things you can do when you have a good genetic system like Drosophila. If you like this sort of thing, be sure to take Genetics (BMB 222 General Genetics) ...
genetic testing for Marfan syndrome
genetic testing for Marfan syndrome

... people with Loeys-Dietz syndrome, a connective tissue disorder caused by mutations in the TGFBR1 or TGFBR2 genes, may have many features of Marfan syndrome. Individuals with LoeysDietz syndrome may also display other unique features such as cleft palate or club foot; however, they do not develop len ...
The physics behind the larger scale organization of DNA in eukaryotes
The physics behind the larger scale organization of DNA in eukaryotes

Epigenetic Control of Apomixis
Epigenetic Control of Apomixis

... been reported to play a key role in gene expression through RNAdirected DNA methylation (RdDM) of genes as well as by inducing histone modifications. Methylated cytosine (5-mC) has been reported to be involved in many important biological processes, including movement of transposable elements (TEs), ...
The Maize Genome Poster
The Maize Genome Poster

... research in maize genetics into practical applications. One event of particular impact was the demonstration of hybrid vigor, or heterosis, which results when two parental varieties, both showing reduced stature caused by inbreeding, are crossed to produce more robust hybrid offspring. Vigorous hybr ...
MB ChB PHASE I
MB ChB PHASE I

... Amino-acids and short peptides are absorbed into mucosal cells by several methods, including ATP-driven Na+-dependent transport like that used for Glc. [Energy Transformations - Carbohydrates Lecture 2] ...
Previous releases and international approvals
Previous releases and international approvals

... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
DOCX version of Canola licence application summary
DOCX version of Canola licence application summary

... phosphotransferase which detoxifies antibiotics such as kanamycin and neomycin, thereby conferring resistance to the bacteria in which the recombinant plasmids are maintained. This is mainly used a selectable marker for the early selection of transformed plants in tissue culture. Short regulatory se ...
The ZYG-1 kinase, a mitotic and meiotic regulator of centriole
The ZYG-1 kinase, a mitotic and meiotic regulator of centriole

... original pole was a duplex, of two functional units (later referred to as polar organizers), each of which had the potential to organize a spindle pole. The authors then made a remarkable set of observations on the fate of the quadrapartitioned poles. During the cell cycle immediately following a qu ...
Evaluation of the tryptophan requirement of small
Evaluation of the tryptophan requirement of small

Replication timing as an epigenetic mark
Replication timing as an epigenetic mark

marker assisted selection in disease resistance breeding
marker assisted selection in disease resistance breeding

... 2001; Collard and Mackill, 2008; Kumar et al. 2011). In recent years, single nucleotide polymorphisms (SNPs), i.e. single base changes in DNA sequence, have become an increasingly important class of molecular markers. The potential number of SNP markers is very high and micro-array procedures have b ...
Biochemistry and biosynthesis of insect pigments
Biochemistry and biosynthesis of insect pigments

... cyclization of linear polyketides via successive condensation of simple carboxylic acid metabolites and occur in two major Superfamilies of Hemiptera, the Coccoidea and Aphidoidae, respectively. Ommochromes, tetrapyrroles and melanins are derived from different amino acid precursors, tryptophan, gly ...
Mutations of genes in synthesis of the
Mutations of genes in synthesis of the

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Artificial gene synthesis

Artificial gene synthesis is a method in synthetic biology that is used to create artificial genes in the laboratory. Currently based on solid-phase DNA synthesis, it differs from molecular cloning and polymerase chain reaction (PCR) in that the user does not have to begin with preexisting DNA sequences. Therefore, it is possible to make a completely synthetic double-stranded DNA molecule with no apparent limits on either nucleotide sequence or size. The method has been used to generate functional bacterial or yeast chromosomes containing approximately one million base pairs. Recent research also suggests the possibility of creating novel nucleobase pairs in addition to the two base pairs in nature, which could greatly expand the possibility of expanding the genetic code.Synthesis of the first complete gene, a yeast tRNA, was demonstrated by Har Gobind Khorana and coworkers in 1972. Synthesis of the first peptide- and protein-coding genes was performed in the laboratories of Herbert Boyer and Alexander Markham, respectively.Commercial gene synthesis services are now available from numerous companies worldwide, some of which have built their business model around this task. Current gene synthesis approaches are most often based on a combination of organic chemistry and molecular biological techniques and entire genes may be synthesized ""de novo"", without the need for precursor template DNA. Gene synthesis has become an important tool in many fields of recombinant DNA technology including heterologous gene expression, vaccine development, gene therapy and molecular engineering. The synthesis of nucleic acid sequences is often more economical than classical cloning and mutagenesis procedures.
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