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Translocation Arrest by Reversible Folding of a Precursor Protein
Translocation Arrest by Reversible Folding of a Precursor Protein

... made use of the following observation. Import and processing of a fusion protein between a mitochondrial presequence (amino acid residues 1-22 of cytochrome oxidase subunit IV) and dihydrofolate reductase (DHFR) t was found to be inhibited after binding of the folate antagonist methotrexate to the D ...
Comparative Analysis of Prothrombin Activators
Comparative Analysis of Prothrombin Activators

... activator, present only in snakes containing group C complexes, also showed a very high degree of homology (96%–98%). Expression of both the factor X– and factor V–like proteins determined by immunoblotting provided an additional means of separating these two groups at the molecular level. The molec ...
From Amino Acid to Glucosinolate Biosynthesis: Protein Sequence
From Amino Acid to Glucosinolate Biosynthesis: Protein Sequence

... mass of these proteins in both full-length and regulatory domaintruncated forms was estimated by calibrated gel filtration chromatography (Table 3). The position of the eluting protein was measured by UV absorbance at 280 nm and by measuring the enzyme activity of eluted fractions with the DTNB assa ...
Genes for two multicopper proteins required for Fe(III) oxide
Genes for two multicopper proteins required for Fe(III) oxide

... multicopper protein OmpB for Fe(III) oxide reduction. A homologue of OmpB, designated OmpC, which is 36 % similar to OmpB, has been discovered in the G. sulfurreducens genome. Deletion of ompC inhibited reduction of insoluble, but not soluble Fe(III). Analysis of multiple Geobacter and Pelobacter ge ...
Enhancement of the Essential Amino Acid Composition of Food
Enhancement of the Essential Amino Acid Composition of Food

Metabolism of sucrose and its five isomers by
Metabolism of sucrose and its five isomers by

... adjacent to malH (designated malB) also encodes a putative EII(CB) protein that is " 60 % identical with AglA of K. pneumoniae. Coincident with our studies, publication of the complete genome sequence of enterohaemorrhagic E. coli O157 : H7 (Perna et al., 2001) also revealed two adjacent genes with ...
SNP Analysis (GAW15 data)
SNP Analysis (GAW15 data)

... Chromosome 6: known strong genetic factors conforms well to the expected frequency of Hardy-Weinberg disequilibrium with this large set of markers. ...
soy protein concentrate - US Soybean Export Council
soy protein concentrate - US Soybean Export Council

... selected and cleaned as the first step in soy product processing. The clean soybeans are dehulled, then the oil is extracted for cooking, biodiesel and other uses. The residue, consisting of defatted white flakes, can then be ground to make soy flour, toasted and ground to make soybean meal, or subj ...
transition metal complexes of amino acid and peptide derivatives
transition metal complexes of amino acid and peptide derivatives

... formation processes has already been widely studied. However the presence of carboxylate groups in the side chain modifies the charge of the ligands and the complexes. We have investigated the copper(II) and nickel(II) complexes of di-, tri- and tetra-peptides containing one, two or more aspartic an ...
Biosc_48_Chapter_5_lecture
Biosc_48_Chapter_5_lecture

... between the inner and outer membranes. b. This sets up a huge concentration gradient of H+ between the membranes. c. H+ can only move through the inner membrane through structures called respiratory assemblies d. Movement of H+ across the membrane provides energy to the enzyme ATP synthase, which co ...
Identification of functional domains in Arabidopsis thaliana mRNA
Identification of functional domains in Arabidopsis thaliana mRNA

... identified by bioinformatics searches in over 360 species (14). Nudix enzymes catalyse the hydrolysis of a wide range of small nucleotide substrates composed of a nucleoside diphosphate linked to another moiety X, hence the name Nudix (14). All members of this superfamily share a conserved amino acid ...
Metabolite Markers
Metabolite Markers

... Pyroglutamic acid is a metabolite of glutathione. Glutathione serves as an antioxidant and is also conjugated to toxic compounds in the liver. Elevated values are most commonly caused by glutathione deficiency due to toxic exposure, such as acetaminophen toxicity. Elevated pyroglutamic acid may also ...
- Ex Student Archive
- Ex Student Archive

... optimal ratio of fat and lean meat. Also, perceived meat quality may include ethical aspects, like animal welfare and sustainable production systems. The latter aspects are, however, not further addressed in this study in which meat quality is referred to as technological and sensory quality/palatab ...
Importance of integrons in the diffusion of resistance
Importance of integrons in the diffusion of resistance

... and integration of DNA units, by performing two consecutive strand breakage and rejoining steps. These steps take place without DNA synthesis or the intervention of high-energy cofactors (such as ATP). This conservative feature distinguishes sitespecific recombination from transposition, in which a ...
Populus trichocarpa
Populus trichocarpa

... – Direct positive selection – are some of these alleles conditionally advantageous? ...
The regulation of fatty acid biosynthesis in some
The regulation of fatty acid biosynthesis in some

... Gas-liquid chromatographic analysis. Fatty acids of Inp3 were methylated and analysed as described in Intriago & Floodgate (1991). Radio-HPLC analysis. Fatty acids of Inp2 were derivatized using a technique adapted from that of Lam & Gruska (1985). Derivatization was started by adding 20 p1 5 % (w/v ...
Genetics of Male Infertility - the Infertility Center of St. Louis
Genetics of Male Infertility - the Infertility Center of St. Louis

... The unusually repetitive sequence structure of the AZFc region of the Y plagued even the first attempts at constructing a physical map with YAC’s, because repetitive STS’s could not be accurately placed in what was then called deletion intervals 6D-6F. Even the size of AZFc (without an accurate sequ ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.

... KISS1R was identified in a girl with central precocious puberty not only did this observation reinforce the notion that kisspeptin is an important gatekeeper of pubertal function in the human, but it was also the first identification of loss and gain-of-function mutations critical to the hypothalami ...
23 Amino Acids, Peptides, and Proteins
23 Amino Acids, Peptides, and Proteins

... Why D-sugars and L-amino acids? While it makes no difference which isomer nature “selected” to be synthesized, it is important that the same isomer be synthesized by all organisms. For example, if mammals ended up having L-amino acids, then L-amino acids would need to be the isomers synthesized by t ...
Evaluation of the Water Stress-Inducible
Evaluation of the Water Stress-Inducible

... cytoplasm to become increasingly viscous. This increases the chance of molecular interactions that can cause protein denaturation and aggregation (Hoekstra et al., 2001). Osmotic stress and dehydration also cause destabilization of cellular membranes due to the insertion of amphiphillic substances i ...
October 12 AP Biology - John D. O`Bryant School of Math & Science
October 12 AP Biology - John D. O`Bryant School of Math & Science

... B) force the cell to rely on lipids for energy. C) result in the conversion of kinetic energy to potential energy.  D) force the cell to rely on ADP for energy.  E) have no effect on the cell. ...
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter
DNA Base Sequence Homology in Rhizoctonia solani Kuihn: Inter

The Role of TP53 in Cervical Carcinogenesis
The Role of TP53 in Cervical Carcinogenesis

... called ubiquitin-protein ligase E3A or UBE3A), which functions as an ubiquitin protein ligase. The dimeric complex then binds p53 and E6AP catalyzes multi-ubiquitination and degradation of p53. The ability to promote p53 degradation is an exclusive property of E6 from the high-risk HPV types. Indeed ...
Gene Section HDAC2 (histone deacetylase 2) Atlas of Genetics and Cytogenetics
Gene Section HDAC2 (histone deacetylase 2) Atlas of Genetics and Cytogenetics

... growth. HDAC2 knockdown-induced G(1)-S cell cycle arrest and restored activity of p16(INK4a) and the proapoptotic factors. ...
WW Genetic Counselor English - Wonderwise
WW Genetic Counselor English - Wonderwise

... genetic counselor. Cathy works in a hospital clinic, where she sees people of all ages. Adults and kids visit her with different kinds of health problems that might be passed on from one generation to the next. You probably know that we inherit features such as our hair or eye color from our parents ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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