
by Attila Mokanszki Supervisor: Prof. Dr. Eva Olah
... hibridisation (FISH) is capable of determining numerous sperm cells numerical chromosome aberration at the same time. The simplest method for the determination of sperm sample estimated numerical chromosome aberrations is the so-colled conservative method by which the frequency of one autosome and t ...
... hibridisation (FISH) is capable of determining numerous sperm cells numerical chromosome aberration at the same time. The simplest method for the determination of sperm sample estimated numerical chromosome aberrations is the so-colled conservative method by which the frequency of one autosome and t ...
Uptake and assimilation of nitrogen from solutions containing
... Hempstead, UK). The uptake of the 15N labelled compounds was determined using the equations of Millard & Nielsen (1989). From the observed rates of uptake (see Results) it was estimated that depletion of any individual form of N from the uptake solution ranged from 7% (nitrate in the mixed nutrient ...
... Hempstead, UK). The uptake of the 15N labelled compounds was determined using the equations of Millard & Nielsen (1989). From the observed rates of uptake (see Results) it was estimated that depletion of any individual form of N from the uptake solution ranged from 7% (nitrate in the mixed nutrient ...
NCBI Molecular Biology Resources
... NM_000547: variant 1 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M17755.2 and AW874082.1. On Feb 25, 2003 this sequence version replaced gi:21361188. ...
... NM_000547: variant 1 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from M17755.2 and AW874082.1. On Feb 25, 2003 this sequence version replaced gi:21361188. ...
This document has been downloaded from Tampub – The
... be interviewed in 147 cases. The questionnaire included a review of risk factors including hypertension, diabetes, past and recent smoking, drinking habits and previous illnesses. On the basis of these interviews, men were classified as smokers or non-smokers. Ex-smokers were included in the categor ...
... be interviewed in 147 cases. The questionnaire included a review of risk factors including hypertension, diabetes, past and recent smoking, drinking habits and previous illnesses. On the basis of these interviews, men were classified as smokers or non-smokers. Ex-smokers were included in the categor ...
evolution - Santa Fe Institute
... But what is the origin of this observed robustness? Is it merely an accident, or a consequence of natural selection in the face of mutations and environmental variation? And what are the evolutionary consequences of robustness? The amount of phenotypic diversity within or among populations can vary ...
... But what is the origin of this observed robustness? Is it merely an accident, or a consequence of natural selection in the face of mutations and environmental variation? And what are the evolutionary consequences of robustness? The amount of phenotypic diversity within or among populations can vary ...
Tetrahymena Contain Two Distinct and Unusual High Mobility Group
... Examination of the pattern of LG-1 and LG-2 synthesis during the sexual phase of the life cycle, conjugation, demonstrates that the synthesis of LG-1 and LG-2 is coordinately increased from basal levels during the differentiation of new macronuclei (7-13 h), suggesting that both of these proteins pl ...
... Examination of the pattern of LG-1 and LG-2 synthesis during the sexual phase of the life cycle, conjugation, demonstrates that the synthesis of LG-1 and LG-2 is coordinately increased from basal levels during the differentiation of new macronuclei (7-13 h), suggesting that both of these proteins pl ...
Analysis of Nutrient Composition of Feather Meal and Feather Meal
... representative nutrient analysis must be provided for ration formulation. It is conceivable that, in the future, further restrictions may be placed on use of ruminant-derived byproducts. If this occurs, then having accurate and complete nutrient profiles on feather meal products would position them ...
... representative nutrient analysis must be provided for ration formulation. It is conceivable that, in the future, further restrictions may be placed on use of ruminant-derived byproducts. If this occurs, then having accurate and complete nutrient profiles on feather meal products would position them ...
Immunohistochemical and Mutation Analyses Demonstrate that
... transformed cells were grown in Luria broth (LB) medium containing 100 ixg/ml ampicillin and 25 ~g/ml kanamycin. Expression of the fusion proteins was induced by the addition of isopropyl 13-thiogalactopyranoside (Boehringer-Mannheim Corp.) to a final concentration of 2 mM. 3 h after induction, cell ...
... transformed cells were grown in Luria broth (LB) medium containing 100 ixg/ml ampicillin and 25 ~g/ml kanamycin. Expression of the fusion proteins was induced by the addition of isopropyl 13-thiogalactopyranoside (Boehringer-Mannheim Corp.) to a final concentration of 2 mM. 3 h after induction, cell ...
Methods of Human Heredity Study
... centromeres are constant, and are called constitutive heterochromatic regions serving as chromosome markers. There are other heterochromatic regions, called facultative heterochromatin and represented by whole sex chromosomes, which become heterochromatic only at certain stages. For instance, in fem ...
... centromeres are constant, and are called constitutive heterochromatic regions serving as chromosome markers. There are other heterochromatic regions, called facultative heterochromatin and represented by whole sex chromosomes, which become heterochromatic only at certain stages. For instance, in fem ...
Genotype C of hepatitis B virus can be classified into at least two
... of HBV genotype have also been reported in genotypes A (A9 and A-A9) (Bowyer et al., 1997; Kramvis et al., 2002) and B (Ba and Bj) (Sugauchi et al., 2002a). The genotyping of HBV is important for clarifying the route of infection with and virulence of the virus. In particular, examination of sequenc ...
... of HBV genotype have also been reported in genotypes A (A9 and A-A9) (Bowyer et al., 1997; Kramvis et al., 2002) and B (Ba and Bj) (Sugauchi et al., 2002a). The genotyping of HBV is important for clarifying the route of infection with and virulence of the virus. In particular, examination of sequenc ...
Properties of Mitotic and Meiotic Recombination in the
... plasmid but not within the CUP1 repeats. The samples were analyzed using CHEF gels as described above. We generated CUP1-specific probes using the primers CUP1 amp5* and CUP1 amp3*; probes specific to the pBR322 portion of YIp5 were produced using the probes bla-F and bla-R. For transformants with a ...
... plasmid but not within the CUP1 repeats. The samples were analyzed using CHEF gels as described above. We generated CUP1-specific probes using the primers CUP1 amp5* and CUP1 amp3*; probes specific to the pBR322 portion of YIp5 were produced using the probes bla-F and bla-R. For transformants with a ...
1 FRQ-interacting RNA Helicase (FRH) Mediates Negative and
... leads to high WCC activity accompanied by rapid transcription-associated turnover. FRH overexpression promotes WC-1 accumulation, confirming that FRH together with FRQ plays a role in WC-1 stabilization. Identification of a viable allele of frh displaying virtually complete loss of both negative and ...
... leads to high WCC activity accompanied by rapid transcription-associated turnover. FRH overexpression promotes WC-1 accumulation, confirming that FRH together with FRQ plays a role in WC-1 stabilization. Identification of a viable allele of frh displaying virtually complete loss of both negative and ...
Novel p53 mutants selected in BRCA
... but also demonstrates a modest gain of function transforming phenotype (Crook et al., 1994; Rowan et al., 1996). Interestingly, mice null for Bax retain a normal p53-dependent apoptotic programme (Knudson et al., 1995). In the present study we have investigated the properties of a series of p53 muta ...
... but also demonstrates a modest gain of function transforming phenotype (Crook et al., 1994; Rowan et al., 1996). Interestingly, mice null for Bax retain a normal p53-dependent apoptotic programme (Knudson et al., 1995). In the present study we have investigated the properties of a series of p53 muta ...
Document
... • Alignment is simulated as Markov process, all sequence positions are seen as independent • Chances of sequence events are independent – Therefore, probabilities per aligned position need to be multiplied – Amino acid matrices contain so-called log-odds values (log10 of the probabilities), so proba ...
... • Alignment is simulated as Markov process, all sequence positions are seen as independent • Chances of sequence events are independent – Therefore, probabilities per aligned position need to be multiplied – Amino acid matrices contain so-called log-odds values (log10 of the probabilities), so proba ...
Random Mutagenesis of Luciola mingrelica Firefly Luciferase
... for the wild type luciferase (table). Bell-shaped dependence of the activity upon pH with maximum at 7.8-8.0 was conserved for all mutant enzymes as well as for the native enzyme. Thermal inactivation studies at 42°C showed that this process is well described by a single exponential; therefore, the ...
... for the wild type luciferase (table). Bell-shaped dependence of the activity upon pH with maximum at 7.8-8.0 was conserved for all mutant enzymes as well as for the native enzyme. Thermal inactivation studies at 42°C showed that this process is well described by a single exponential; therefore, the ...
regulation of fatty acid synthesis
... that changes in these parameters between dark and light conditions could account for increased ACCase activity upon illumination of chloroplasts. Finally, ACCase activity and protein levels are coincident with increases and decreases in oil biosynthesis in developing seeds (e.g. 80, 107; but see 40a ...
... that changes in these parameters between dark and light conditions could account for increased ACCase activity upon illumination of chloroplasts. Finally, ACCase activity and protein levels are coincident with increases and decreases in oil biosynthesis in developing seeds (e.g. 80, 107; but see 40a ...
- BioMedSearch
... whose use can be limited by feedback inhibition. Overexpression of feedback insensitive DAHP synthase isozymes have been used in microbial syntheses of commercially important products such as aromatic amino acids, phenylalanine and tryptophan [17]. The discovery of the existence of a phosphorylation ...
... whose use can be limited by feedback inhibition. Overexpression of feedback insensitive DAHP synthase isozymes have been used in microbial syntheses of commercially important products such as aromatic amino acids, phenylalanine and tryptophan [17]. The discovery of the existence of a phosphorylation ...
Relació estructura-funció en la família de transportadors d'aminoàcids heteromultimèrics.
... related to neurotransmission (the GABA transporter GAT1 and the glutamate transporter GLT-1), these data allowed microsequencing or generation of specific antibodies that have been used to isolate cDNA clones (184, 424). Alternative strategies and serendipity allowed the identification of up to 22 c ...
... related to neurotransmission (the GABA transporter GAT1 and the glutamate transporter GLT-1), these data allowed microsequencing or generation of specific antibodies that have been used to isolate cDNA clones (184, 424). Alternative strategies and serendipity allowed the identification of up to 22 c ...
Access Presentation
... • Spleens from Mdm2SNP309G/G mice had elevated levels of Mdm2 and lower levels of p53 • Presence of 2 Mdm2SNP309G alleles significantly inhibited p53-dependent apoptosis in response to DNA damage in wild-type and heterozygous mutant p53 backgrounds • Presence of Mdm2SNP309G allele attenuates activat ...
... • Spleens from Mdm2SNP309G/G mice had elevated levels of Mdm2 and lower levels of p53 • Presence of 2 Mdm2SNP309G alleles significantly inhibited p53-dependent apoptosis in response to DNA damage in wild-type and heterozygous mutant p53 backgrounds • Presence of Mdm2SNP309G allele attenuates activat ...
Population Genetics A Concise Guide - IB-USP
... understood. The reader should return to theoverview after mastering the chapter and enjoy the experience of understanding what was previously mysterious. Each chapter of the text builds on the previous ones. A few sections contain more advanced material, which is not used in the rest of the book and ...
... understood. The reader should return to theoverview after mastering the chapter and enjoy the experience of understanding what was previously mysterious. Each chapter of the text builds on the previous ones. A few sections contain more advanced material, which is not used in the rest of the book and ...
Crystallization and X Ray Diffraction Data Analyses of the Enzyme
... Bank, PDB, codes 1uwk, 2fkn and 1x8724], however, it is noteworthy that the highest identity [to the one from Pseudomonas putida21] is 36 % and none of them are from a protozoan organism. The elucidation of Trypanosoma cruzi Urocanate Hydratase (TcUH) three-dimensional structure by X ray crystallogr ...
... Bank, PDB, codes 1uwk, 2fkn and 1x8724], however, it is noteworthy that the highest identity [to the one from Pseudomonas putida21] is 36 % and none of them are from a protozoan organism. The elucidation of Trypanosoma cruzi Urocanate Hydratase (TcUH) three-dimensional structure by X ray crystallogr ...
as a PDF
... In L. lactis, respiration growth results in improved biomass, higher pH, and markedly greater long-term survival of lactococci (12, 16). However, the mechanisms involved in this stimulation are not yet understood. One reason is that only a limited number of genetic components involved in respiration ...
... In L. lactis, respiration growth results in improved biomass, higher pH, and markedly greater long-term survival of lactococci (12, 16). However, the mechanisms involved in this stimulation are not yet understood. One reason is that only a limited number of genetic components involved in respiration ...
Mak5 and Ebp2 Act Together on Early Pre-60S Particles and
... Ribosomes are the molecular machines that translate mRNAs into proteins. The synthesis of ribosomes is therefore a fundamental cellular process and consists in the ordered assembly of 79 ribosomal proteins (r-proteins) and four ribosomal RNAs (rRNAs) into a small 40S and a large 60S ribosomal subuni ...
... Ribosomes are the molecular machines that translate mRNAs into proteins. The synthesis of ribosomes is therefore a fundamental cellular process and consists in the ordered assembly of 79 ribosomal proteins (r-proteins) and four ribosomal RNAs (rRNAs) into a small 40S and a large 60S ribosomal subuni ...
Point mutation

A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.