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Fatty Acid Oxid - Univerzita Karlova v Praze
Fatty Acid Oxid - Univerzita Karlova v Praze

... endoplasmic reticulum (ER).  Fatty acid elongation within mitochondria involves the b-oxidation pathway running in reverse, but NADPH serves as electron donor for the final reduction step.  Fatty acids esterified to CoA are substrates for the ER elongation machinery, which uses malonyl-CoA as dono ...
Fatty Acid Oxid
Fatty Acid Oxid

... endoplasmic reticulum (ER).  Fatty acid elongation within mitochondria involves the b-oxidation pathway running in reverse, but NADPH serves as electron donor for the final reduction step.  Fatty acids esterified to CoA are substrates for the ER elongation machinery, which uses malonyl-CoA as dono ...
Control of Fatty-Acid Biosynthesis by Long
Control of Fatty-Acid Biosynthesis by Long

... with the lipid added (not shown). Curve 111: acetylCoA carboxylase was replaced by its product malonylCoA while the other conditions were identical to those of the experiment of curve 11. The main difference to the experiment of curve I1 is the about four-fold increase of long-chain acyl-CoA formati ...
Proviral amplification of the Gypsy endogenous retrovirus of
Proviral amplification of the Gypsy endogenous retrovirus of

... female larvae. The ovoD1 dominant sterile mutant prevents the normal development of the female germline. Either mutational inactivation of this antimorphic allele or its elimination from the homozygous cells generated by mitotic crossing-over are the only events to possibly result in fertile germina ...
Transport of amino acids (L-valine, L-lysine, L
Transport of amino acids (L-valine, L-lysine, L

... to about 65% (Lanfermeijer et al., 1990). At this stage the cotyledons are full-grown and about one-third of the ®nal amount of storage proteins has already been deposited. In soybean cotyledons (water content ;80%), the uptake of 2-aminoisobutyric acid and L-glutamine is also dominated by a linear ...
AMP-activated protein kinase regulation of fatty acid oxidation in the
AMP-activated protein kinase regulation of fatty acid oxidation in the

... oxidation in isolated working rat hearts [21,22,39,56]. It has been well established that AMPK is able to phosphorylate both isoforms of ACC [47–49] and we have shown that cardiac ACC co-purifies with the α2 isoform of the catalytic subunit of AMPK [58]. These studies suggest a tight association of ...
Endoplasmic Reticulum-Located PDAT1
Endoplasmic Reticulum-Located PDAT1

... the castor bean (Ricinus communis L.), even though it is synthesized in phospholipids, which indicates that the castor plant has an editing enzyme, which functions as a phospholipid:diacylglycerol acyltransferase (PDAT) that is specific to ricinoleic acid. Transgenic plants containing fatty acid 12 ...
Table 2
Table 2

... From the *Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Texas; yInstitut Universitaire de Cardiologie et de Pneumologie de Québec, Department of Molecular Medicine, Laval University, Québec City, Québec, Canada; zDepartment of Anesthesiology, Periope ...
lilliputian - Development - The Company of Biologists
lilliputian - Development - The Company of Biologists

... isolate a large number of alternatively spliced cDNA clones, including one species that apparently encoded a full-length cDNA (Fig. 1D). Comparison of cDNA sequence to genomic sequence revealed a large transcription unit that spans approx. 68 kb (Fig. 1D). The gene contains 13 exons and the full-len ...
Proceedings as -file
Proceedings as -file

... ƒ Comparison test: Comments from Duty Laboratory South Africa; Comments from Computing Laboratory The Netherlands; Discussion ƒ ISAG panels: Do they work well? How many laboratories are using these panels in the routine? Do we need changes? Standard / Reference samples? • Nomenclature: Is there a ne ...
projects - Computer Science and Engineering
projects - Computer Science and Engineering

... Vineet Bafna ...
C57BL/6 - Envigo
C57BL/6 - Envigo

... Genetic drift is the change in frequency in which a gene appears in a population, through mutation, regardless of the adaptive value of the mutation. In an inbred population, natural random mutation occurs rather infrequently. Genetic drift is a normal process for any breeding population and thus ca ...
Defining characteristics of Tn5 Transposase non
Defining characteristics of Tn5 Transposase non

... While non-specific DNA plays a role in target localization for many recombinases, transcription factors and restriction enzymes, the importance of nonspecific DNA interactions for transposases has not been investigated. Here, we discuss non-specific DNA-Tn5 Transposase (Tnp) interactions and suggest ...
Glutathione as an endogenous sulphur source in the
Glutathione as an endogenous sulphur source in the

... et al., 1988) in this organism. A role for GSH in sulphur metabolism was apparently not previously envisaged in studies of yeast metabolism (Jones & Fink, 1982; Ono et al., 1988). GSH was, however, cited as a growth factor for micro-organisms (see Penninckx & Jaspers, 1982). It also appears to be an ...
Why should we study B12 and Folate? Deficiencies in both are still
Why should we study B12 and Folate? Deficiencies in both are still

... B12 is stored in the liver o Supply is sufficient for 3-5 years o RDA of 2 µg per day o Pernicious Anemia—Lack of B12 due to lack of intrinsic factor (result of deteriorating stomach lining) o B12 is only made by microorganisms, but is richest in meat.  B12 travels up the food chain B12 Uptake o B1 ...
Proteomic analyses of Oryza sativa mature pollen reveal novel
Proteomic analyses of Oryza sativa mature pollen reveal novel

... understood [5, 6], but little biochemical and molecular genetic information exists on pollen functions. Some recent studies have tried to break the bottleneck. Transcriptomic analyses of Arabidopsis pollen have identified some transcripts expressed preferentially in pollen [7,8]. Functional classifi ...
Graph-based Methods for the Design of DNA - TUBdok
Graph-based Methods for the Design of DNA - TUBdok

Mosaic Isodicentric Y Chromosome in a Patient with Mixed Gonadal
Mosaic Isodicentric Y Chromosome in a Patient with Mixed Gonadal

... chromosome Y probe revealed that the derivative chromosome is a Y chromosome, without translocation a heterochromatic region on Yq was not observed by CBG banding. FISH examination by probes for the SRY region and whole chromosome Y revealed that the derivative chromosome is a Y chromosome, and one ...
Stringent Response in Myxococcus xanthus
Stringent Response in Myxococcus xanthus

... Fruiting body formation Starve for amino acids Accumulation of (p)ppGpp Accumulate (p)ppGpp ??Starve for aa Fruiting bodies Is this a causal relationship? Is there a connection between initiation of fruiting body development and (p)ppGpp accumulation? ...
Malo-ethanolic fermentation in Saccharomyces and
Malo-ethanolic fermentation in Saccharomyces and

... of these dicarboxylic acids. The transport of the two dicarboxylic acids was shown to be strongly inducible by either fumarate or L-malate, while kinetic studies suggest that the same protein transports both dicarboxylic acids. In the K()) yeasts Z. bailii and Sch. pombe, L-malic acid transport was ...
Chance and Necessity in Arthur Peacocke`s Scientific Work
Chance and Necessity in Arthur Peacocke`s Scientific Work

... him on the path of pondering the nature of the interaction of living matter with the non-living world and communion of the whole of creation. At the very root of his subsequent deep thoughts on the nature of the universe and laws of creation, lay these first experiments. For somebody else, those cou ...
Two Classes of sir3 Mutants Enhance the sir1
Two Classes of sir3 Mutants Enhance the sir1

... partial mating-defective phenotype due to an epigenetic phenomenon in which the silent mating-type genes in some cells of the population are completely derepressed yet in other cells the HM genes are fully repressed (Pillus and Rine 1989). To identify genes that contribute to silencing in the popula ...
Powerpoint template for scientific posters (Swarthmore College)
Powerpoint template for scientific posters (Swarthmore College)

... We also did systematic and comprehensive screen of the entire third chromosome (approximately 40% of the genome, involved screening about 112 deficiencies). The brown regions were tested by Wheeler ten years old. The black, red, and green regions were tested in this summer. The black regions are neg ...
Help Me Understand Genetics
Help Me Understand Genetics

... mutations are also called germline mutations because they are present in the parent’s egg or sperm cells, which are also called germ cells. When an egg and a sperm cell unite, the resulting fertilized egg cell receives DNA from both parents. If this DNA has a mutation, the child that grows from the ...
B.Sc. Biomedical Sciences
B.Sc. Biomedical Sciences

... Core courses of the first two semesters are introductory courses in organic chemistry relevant to biology, biology of the cell, the basic building units of an organism, human physiology a glimpse at the orchestrated functioning of organ systems and the basic principles of genetics as seen in nature. ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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