• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Neuron the Memory Unit of the Brain
Neuron the Memory Unit of the Brain

... the heart to pump blood to the body; liver and kidney cells form a filtration system to rid the body of excessive or toxic materials; and skin cells form a protective barrier to the external environment. Each basic cell is a functional unit; it can perform its function alone. Neurons, on the other h ...
The Basics of Brain Development | SpringerLink
The Basics of Brain Development | SpringerLink

... Genes and Gene Products Genes are the material substance that is passed intergenerationally from parent to offspring. Genes are contained in the nucleotide sequences of DNA that are found in the nucleus of every cell in the body. The expression of a gene has one result: the production of a protein m ...
Nanotechnology for Alzheimer`s disease detection and treatment
Nanotechnology for Alzheimer`s disease detection and treatment

... multiphoton microscopy ...
The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period
The plasticity of human maternal brain: longitudinal changes in brain anatomy during the early postpartum period

... positive feelings on her baby may facilitate the increased levels of gray matter volume. fMRI studies with human mothers have similarly shown that greater substantia nigra responses to infant stimuli were correlated with the mother’s self-reported positive emotional reactions to infant stimuli (Bart ...
Rabies (Rhabdovirus)
Rabies (Rhabdovirus)

... Antibody Testing Send cross section of brain stem (through the medulla, pons, or midbrain area) and cerebellum (through EACH hemisphere and the vermis). Many laboratories will not start ancillary testing until negative rabies results have been received. Contact the laboratory for specific policies a ...
Renin-Angiotensin System: I
Renin-Angiotensin System: I

... uterus and placenta, and in fetal membranes, and prorenin is found in amniotic fluid. In addition, components of this system have also been identified in the eyes, exocrine pancreas, heart, adrenal cortex, testes, ovaries, anterior pituitary, pineal, and brain. Although these local systems do not ap ...
- Wiley Online Library
- Wiley Online Library

... closely associated with specific proteolytic events, especially the altered endosomal/lysosomal system (Benowitz et al., 1989; Cole et a!., 1989; Golde et a!., 1992; Haass et al., 1992), and that the amyloidogenic APP fragments are routinely produced in an acidic compartment by noncysteine proteases ...
lmmunohistochemical Localization of Neuronal Nicotinic Receptors
lmmunohistochemical Localization of Neuronal Nicotinic Receptors

... chicken brain indicate that different neuronal AChRs are contained in axonal projections to the optic lobe in the midbrain from neurons in the lateral spiriform nucleus and from retinal ganglion cells. Monoclonal antibodies to the chicken and rat brain AChRs also label apparently identical regions i ...
In utero administration of Ad5 and AAV pseudotypes to the
In utero administration of Ad5 and AAV pseudotypes to the

... vector tropisms and gene-delivery efficiencies in the fetal brain difficult. We have shown previously that an integration-deficient lentivirus can mediate efficient long-term gene delivery to the fetal brain with no significant immune response and enhanced viral spread compared with the adult brain.12 Th ...
to a  of the units.
to a of the units.

... work together as a class to create a model of the nervous system. The outline of a student’s body is traced on a large piece of paper. A cardboard cut out of the brain and spinal cord are placed in the outline to represent the central nervous system. Two colors of yarn, representing the motor and se ...
Models for proconvulsant drugs and precautions for
Models for proconvulsant drugs and precautions for

... MRP, BCRP properties Administration a violent and involuntary related muscular activity (as a Brain Co-medication consequence of brain seizure) of concentration one or several muscles which are Route part of an organ, or of limbs, or Cmax generalized to all the body Acute Single dose detected throug ...
Why are brain pathways
Why are brain pathways

... receptive fields by increasing depolarization (which will increase firing) while stimuli in the periphery of the receptive field will hyperpolarize them (which will make the cell less likely to fire). The cell fires best when the stimulus covers only the central excitatory part of the receptive fiel ...
Multidrug resistance in epilepsy: rats with drug
Multidrug resistance in epilepsy: rats with drug

... drug uptake into the brain by intrinsic or acquired overexpression of multidrug transporters in the blood–brain barrier (BBB) (Sisodiya, 2003). There is now a body of evidence that multidrug transporters such as P-glycoprotein (Pgp; ABCB1) are overexpressed in capillary endothelial cells and astrocy ...
Freud Returns - Socialscientist.us
Freud Returns - Socialscientist.us

... basic emotional-control systems with our primate relatives and with all mammals. At the deep level of mental organization that Freud called the id, the functional anatomy and chemistry of our brains is not much different from that of our favorite barnyard animals and household pets. Modern neuroscie ...
An Introduction To Human Neuroanatomy
An Introduction To Human Neuroanatomy

... many layers of the membrane wrapped around them, and thus being insulated with many layers of myelin. ...
Neuroscientists are finding that their biological
Neuroscientists are finding that their biological

... basic emotional-control systems with our primate relatives and with all mammals. At the deep level of mental organization that Freud called the id, the functional anatomy and chemistry of our brains is not much different from that of our favorite barnyard animals and household pets. Modern neuroscie ...
Signaled drug delivery and transport across the blood
Signaled drug delivery and transport across the blood

... of FUS. The relationship between intravenous drug and the drug concentration in the tissue after FUS treatment may lead to adjustments to clinically prescribed dosages [5]. The dose that is delivered to the target site will depend on the liposomes (concentration, drug loading, responsiveness), the F ...
ANIMALIA
ANIMALIA

... • lack some organ systems (circulatory, respiratory) • diffusion: reason why small and flat • have others (muscular, nervous, digestive, excretory, reproductive) • nervous system (Fig. 49.2): eye spots, rudimentary brain, nerve cords • cephalization (head); Fig. 33.10, Fig. S4-2 ...
Glioblastoma - The Brain Tumour Charity
Glioblastoma - The Brain Tumour Charity

... It is still not known exactly why glioblastomas begin to grow. The reason for their development is under ongoing investigation, and research is looking at genetic and molecular changes in the cells. Normal cells grow, divide and die in a controlled way, in response to signals from your genes. These ...
Glioblastoma - The Brain Tumour Charity
Glioblastoma - The Brain Tumour Charity

... making the temozolomide less effective. People with less of the MGMT protein, therefore, respond better to chemotherapy and generally survive longer, as the tumour cells cannot repair themselves so well. You can ask for a ‘biomarker’ test called the ‘MGMT methylation test’ to establish your level of ...
Kinetics of a nucleoside release from lactide
Kinetics of a nucleoside release from lactide

... of this compound following systemic administration corresponds to plasma concentration of 40–100 nM whereas cerebrospinal fluid concentration is only 25% that in plasma [5]. It is, therefore, not surprising that a recent clinical study showed ineffectivity of cladribine on gliomas [6]. Intracranial ...
Neuroscience: Exploring the Brain
Neuroscience: Exploring the Brain

... to the cut. Paralysis in this case does not mean that the muscles cannot function but that they cannot be controlled by the brain. The spinal cord communicates with the body via the spinal nerves, which are part of the peripheral nervous system (discussed below). Spinal nerves exit the spinal cord t ...
A Verbose Guide to Dissection of the Sheep`s Brain H
A Verbose Guide to Dissection of the Sheep`s Brain H

... is frequently vertical, while the long axis of the forebrain is always horizontal. Thus the primate CNS contains a permanent flexure that is not present in other vertebrates. For primate brain stem and spinal cord we use the lower coordinate system: ...
Diffusion-Weighted MR Imaging in Brain Tumor
Diffusion-Weighted MR Imaging in Brain Tumor

... fiber orientation along the three orthogonal spatial axes. The precise determination of the margins of the tumor is of the utmost importance to the management of brain tumors. The goal of a surgical approach to the brain neoplasm is the complete resection of the tumor, coupled with minimum neurologi ...
O A
O A

... declines are amplified in age-related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), AD, and Parkinson’s disease (PD). As the elderly population increases, so will the prevalence of these agerelated disorders increase (Nicita-Mauro, 2002). The etiology of these disorders is ...
< 1 ... 11 12 13 14 15 16 17 18 19 ... 127 >

Blood–brain barrier



The blood–brain barrier (BBB) is a highly selective permeability barrier that separates the circulating blood from the brain extracellular fluid (BECF) in the central nervous system (CNS). The blood–brain barrier is formed by brain endothelial cells, which are connected by tight junctions with an extremely high electrical resistivity of at least 0.1 Ω⋅m. The blood–brain barrier allows the passage of water, some gases, and lipid-soluble molecules by passive diffusion, as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function. On the other hand, the blood–brain barrier may prevent the entry of lipophilic, potential neurotoxins by way of an active transport mechanism mediated by P-glycoprotein. Astrocytes are necessary to create the blood–brain barrier. A small number of regions in the brain, including the circumventricular organs (CVOs), do not have a blood–brain barrier.The blood–brain barrier occurs along all capillaries and consists of tight junctions around the capillaries that do not exist in normal circulation. Endothelial cells restrict the diffusion of microscopic objects (e.g., bacteria) and large or hydrophilic molecules into the cerebrospinal fluid (CSF), while allowing the diffusion of small hydrophobic molecules (O2, CO2, hormones). Cells of the barrier actively transport metabolic products such as glucose across the barrier with specific proteins. This barrier also includes a thick basement membrane and astrocytic endfeet.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report