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... problem and underwent a thorough clinical investigation including medical history, cognitive screening (MMSE), physical and neurological examination, laboratory blood tests, apolipoprotein E genotyping, neuropsychological assessment, lumbar puncture, and magnetic resonance imaging/computed tomograph ...
Nuclear receptor coactivators: Regulators of steroid action in brain
Nuclear receptor coactivators: Regulators of steroid action in brain

... decreases SRC-1 expression in the VMH, while estradiol reverses this effect (95). In the hypothalamus of cycling female rats, SRC-1 levels were lowest during diestrus, and highest at proestrus and estrus, suggesting that ovarian hormones up-regulate SRC-1 (96). In contrast, ovariectomy did not alter ...
USF Hyperbaric Biomedical Research Laboratory
USF Hyperbaric Biomedical Research Laboratory

... The USF Hyperbaric Biomedical Research Laboratory is a collaborative research facility housed in the Department of Molecular Pharmacology and Physiology in the laboratories of Dr. Jay B. Dean: MDL 1027 (813-396-9628) and MDC 4042, 4046 (813-974-8863). The HBRL maintains several hyperbaric/hypobaric ...
18 Renal Acid-Base Balance
18 Renal Acid-Base Balance

... levels in the urine are low (too little base). That means that the original problem of decreased carbon dioxide (pCO2) is being compensated for by the kidneys, which need to start reabsorbing more H+ to make more acid in the blood. If they are reabsorbing more H+, they are making less bicarbonate in ...
Autonomic Nervous System
Autonomic Nervous System

... 1. Anhidrosis (reduced sweating) 2. Ptosis (drooping eyelids) 3. Miosis (constricted pupil) Symptoms may also include Enophthalmos (sunken eyes) and vasodilation. ...
Determinants of GFR - BHS116.3 Physiology III
Determinants of GFR - BHS116.3 Physiology III

... Determinants of GFR • GFR = Capillary filtration coefficient X Net filtration pressure. • Increased hydrostatic pressure in Bowman’s capsule decreases GFR (inverse is also true). – Normally, not a primary mechanism for day-to-day regulation of GFR. – Hydrostatic pressure in Bowman’s capsule can cha ...
Optogenetic drive of neocortical pyramidal neurons generates fMRI
Optogenetic drive of neocortical pyramidal neurons generates fMRI

Circuits in Psychopharmacology
Circuits in Psychopharmacology

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Optical recording of electrical activity in intact neuronal networks
Optical recording of electrical activity in intact neuronal networks

... 15 September 2008 / Vol. 16, No. 19 / OPTICS EXPRESS 14910 ...
Multiple hypothalamic circuits sense and regulate glucose levels
Multiple hypothalamic circuits sense and regulate glucose levels

... appear to be the opposite of those of orexin/hypocretin cells. In mice, knockout of MCH increases energy expenditure and reduces body weight (88), and these characteristics are also seen in animals lacking the MCH receptor -1 (MCH1R) (57). Central injection of MCH in rats increases the quantities of ...
[3h]cyclohexyladenosine
[3h]cyclohexyladenosine

... uniform grain density of 2.2 f 0.2 grains/600 pm3. The grain densities defined in this paper as significant were greater than or equal to 3.7 + 0.3 grains/600 pm3 (p < 0.005). All of the autoradiographic results reported have been found in several sections from at least two animals. This procedure h ...
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Document

...  Schwann cells – similar to function of oligodendrocytes but in PNS, can guide axonal regeneration  Astrocytes – largest glia, star-shaped, many functions  Microglia – involved in response to injury or disease Copyright © 2009 Allyn & Bacon ...
Acetylcholinesterase in central vocal control nuclei of the zebra finch
Acetylcholinesterase in central vocal control nuclei of the zebra finch

... 1985), birds (Kusunoki 1969; Medina and Reiner 1994) and mammals (Mesulam 1987), indicating that diverse vertebrate forms have similar cholinergic systems from the brainstem to higher order regions in the forebrain and back. As in mammals parts of the avian basal ganglia demonstrate characteristic c ...
Neurotransmitters: Acetylcholine and Dopamine
Neurotransmitters: Acetylcholine and Dopamine

... paranoid, having hallucinations, and even hearing voices that are not there ...
The Complicated Equation of Smell, Flavor, and Taste
The Complicated Equation of Smell, Flavor, and Taste

... to the study of taste. The olfactory system in vertebrates has a unique embryology. It forms from 1) paired placodes made of non-neural epithelium that have the capacity to give rise to sensory neurons and supporting cells in the olfactory epithelium, and 2) neural crest cells that give origin to th ...
Responses of single neurons in the human brain during flash
Responses of single neurons in the human brain during flash

... be seen by comparing Figures 12-1A and 121B. In this example, during the flash period a photograph of Paul McCartney is shown to the left eye while a grating is presented to the right eye. Yet, depending on which image was already present monocularly, the subject reports seeing only Paul McCartney o ...
Chapter 7 The Nervous System
Chapter 7 The Nervous System

... H. Age-related changes 14. Changes in sympathetic nervous system activity a. Increased norepinephrine secretion + b. Decreased removal of norepinephrine at the synapse + c. ...
Early Microglial Activation Precedes Neuronal Loss in Mouse Model of Progressive
Early Microglial Activation Precedes Neuronal Loss in Mouse Model of Progressive

... patient lymphoblastoid cells, it has been suggested that their increased activity is related to EPM1 pathogenesis (9). However, the precise role of CSTB and the mechanisms by which its loss leads to EPM1 remain poorly understood. A mouse model for EPM1 has been generated by targeted disruption of th ...
Overview of Renal Function Anatomy/Function of the Kidney
Overview of Renal Function Anatomy/Function of the Kidney

Technical note: Use of a double inversion recovery pulse sequence
Technical note: Use of a double inversion recovery pulse sequence

... If the rf transmission field is inhomogeneous, the use of hyperbolic-secant inversion pulses [12] should be considered to correct any resulting variation of tissue suppression across the FOV. Although the head coil used in this study both transmits and receives, it has good rf magnetic field homogen ...
Neurodegeneration with Brain Iron Accumulation: Diagnosis and
Neurodegeneration with Brain Iron Accumulation: Diagnosis and

... and spasticity are usually managed with anticholinergics, benzodiazepines and other anti-spasticity agents such as baclofen, which may be delivered intrathecally. Botulinum toxin injections can also provide targeted relief of dystonia and spasticity. Deep brain stimulation has shown promise, but stu ...
Lecture Guide - TestbankCart.com
Lecture Guide - TestbankCart.com

Principles of Endocrinology - The Central Endocrine Glands
Principles of Endocrinology - The Central Endocrine Glands

... Synergistic – hormones interact so that the end result will be more meaningful as compared to if only one hormone is functioning/several hormones complement each other and combine effects eg: stimulation of mammary glands development by prolactin, estrogen, progesterone and growth hormone Permissive ...
Ch. 3–Biological Basis of Behavior PPT
Ch. 3–Biological Basis of Behavior PPT

... Much higher soft tissue detail than CT scan CONS: More expensive Takes at least 30 minutes fMRI: a 4D image (time) of glucose metabolism ...
Cerebellum: The Brain for an Implicit Self
Cerebellum: The Brain for an Implicit Self

... The primary rationale for my writing this book is that I have been involved in research on the cerebellum for half a century and it seemed appropriate to share with younger generations of researchers how thrilling and dramatic this epoch has been, particularly since research on the cerebellum has ad ...
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Haemodynamic response



In haemodynamics, the body must respond to physical activities, external temperature, and other factors by homeostatically adjusting its blood flow to deliver nutrients such as oxygen and glucose to stressed tissues and allow them to function. Haemodynamic response (HR) allows the rapid delivery of blood to active neuronal tissues. Since higher processes in the brain occur almost constantly, cerebral blood flow is essential for the maintenance of neurons, astrocytes, and other cells of the brain.
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