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Defining the anabolic window of opportunity
Defining the anabolic window of opportunity

... of MPS must exceed MPB, resulting in a positive NBAL over a given period of time. Studies have shown that provision of an amino acid source combined with exercise is required to switch NBAL from negative to positive (6, 11). This switch is largely due to increases in MPS rather than changes in MPB ...
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File

... energy (or ATP) from sugar (glucose). This process is very efficient and produces 38 ATPs for each molecule of glucose. Carbon dioxide and water are the results of this reaction. When muscles undergo rigorous exercise they require more oxygen to make ATP than the blood can supply. At this point the ...
Exam#2-`95
Exam#2-`95

... 10. Inorganic phosphate (Pi) is an acid and its accumulation in muscle contributes to metabolic acidosis. 11. 31P MRS can provide an accurate calculation of intramuscular pH. 12. The creatine kinase reaction, in the direction of ATP regeneration, consumes a proton and thereby functions as a metaboli ...
Stretch Reflexes
Stretch Reflexes

... Copyright © 2010 Pearson Education, Inc. ...
Myofibrillogenesus in Skeletal Muscle Cells
Myofibrillogenesus in Skeletal Muscle Cells

... Myofibrillogenesis in a Mouse Cell Line from Skeletal Muscle How general is this premyofibril model of myofibrillogenesis in skeletal muscle cells? The model originally was developed using embryonic chick muscle cells.20,26 This model also was tested by using a transformed mouse cell line. Myogenic cel ...
promoting training adaptations through nutritional
promoting training adaptations through nutritional

... Widegren et al. 2001; Williams and Neufer 1996). Training and nutrition are highly interrelated in that optimal adaptation to the demands of repeated training sessions typically requires a diet that can sustain muscle energy reserves (Coyle 2000). As nutrient stores (i.e. muscle and liver glycogen) ...
SOMATROPIN (SEDICO)
SOMATROPIN (SEDICO)

... Through GH exerts direct effects in target tissues, many of its physiological effects are mediated indirectly through IGF-I, a potent growth and differentiation factor. The major source of circulating IGF-I is hepatic in origin. Peripheral tissue IGF-I exerts local paracrine actions that appear to b ...
6- Fed Fast Cycle- ENDO
6- Fed Fast Cycle- ENDO

... Brain in fasting During the first few days of fasting, the brain continues to use glucose only as a source of energy. In prolonged fasting (more than 2 -3 weeks), plasma ketone bodies reach elevated levels & are used in addition to glucose in as a source of energy the brain. This reduces the need f ...
fed fast cycle
fed fast cycle

... Brain in fasting During the first few days of fasting, the brain continues to use glucose only as a source of energy. In prolonged fasting (more than 2 -3 weeks), plasma ketone bodies reach elevated levels & are used in addition to glucose in as a source of energy the brain. This reduces the need f ...
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle
Orphan nuclear receptors: therapeutic opportunities in skeletal muscle

... SKELETAL MUSCLE AS AN ENDOCRINE ORGAN: MYOKINES ...
Fatty acid metabolism in adipose tissue, muscle and liver in health
Fatty acid metabolism in adipose tissue, muscle and liver in health

... at this time, again by the action of insulin. Both the liver and skeletal muscle take up fatty acids largely according to their availability. The rate of removal of plasma NEFA is, under most conditions, fairly closely proportional to their plasma concentration. The removal by the liver of remnant-p ...
Muscle Fiber
Muscle Fiber

... ii. Each muscle fiber is innervated by a single nerve ending iii. Each muscle fiber has got an outer membrane made up of glycoprotein, which helps to insulate and separate the muscle fibers from one another iv. The control of these muscle fibers is mainly by nerve signals v. These smooth muscle fibe ...
Lecture Notes - Pitt Honors Human Physiology
Lecture Notes - Pitt Honors Human Physiology

... of If and Ca++ channels. The net result is that cation entry speeds up, which decreases the time required for the voltage-gated Ca++ channels to become activated during each action potential cycle. As a result, the time between action potentials decreases. Typical myocardial cells are also affected ...
Fuel selection in human skeletal muscle in insulin resistance: a
Fuel selection in human skeletal muscle in insulin resistance: a

... Kipnis (5) using rat diaphragm, Beatty and Bocek (6) using isolated sartorius muscle fibers from rhesus monkeys, and Ruderman et al. (7) using the perfused rat hindquarter failed to show that insulin-stimulated glucose uptake was decreased by addition of palmitate or oleate. However, these experimen ...
Recovery Following Exercise
Recovery Following Exercise

... • cool-down continues to provide oxygen to skeletal muscle • which therefore enhances oxidation of lactic acid • and ensures that less lactic acid remains in tissue • and there is less muscle soreness ...
Chapter 9: Mechanisms and Characteristics of Sports Trauma
Chapter 9: Mechanisms and Characteristics of Sports Trauma

... • Grade I - some fibers have been stretched or actually torn resulting in tenderness and pain on active ROM, movement painful but full range present • Grade II - number of fibers have been torn and active contraction is painful, usually a depression or divot is palpable, some swelling and discolorat ...
A novel atlas of gene expression in human skeletal
A novel atlas of gene expression in human skeletal

... De Magalhaes and colleagues [6] conducted a metaanalysis of microarray experiments on aging in mice, rats, and humans across a variety of tissues. In this crossspecies, cross-platform analysis, gene orthologues were meta-analyzed for approximately 400 samples, 42 of which were from human skeletal mu ...
Aerobic Dance Study Guide Section 1: Why participate in a fitness
Aerobic Dance Study Guide Section 1: Why participate in a fitness

... Soluble fiber helps remove cholesterol articles from your digestive system, helps control blood sugar because it isn’t well absorbed, adds bulk to your stool, and helps you feel full without adding calories to your diet. Insoluble fiber also helps in weight control by helping you feel full, and he ...
Metabolic effects of very-low-carbohydrate diets
Metabolic effects of very-low-carbohydrate diets

... oxidized to CO2 and H2O in the citric acid cycle. However, when the rate of mobilization of fatty acids from adipose tissue is accelerated, as, for example, during very low carbohydrate intake, the liver converts acetyl CoA into ketone bodies: Acetoacetate and 3-hydroxybutyrate. The liver cannot uti ...
Raised plasma G-CSF and IL-6 after exercise may play a role in
Raised plasma G-CSF and IL-6 after exercise may play a role in

... present study, it is a related study. However, there were two points of difference between the two studies. The present study showed that G-CSF (not M-CSF) and IL-6 might also regulate neutrophilia and that this regulation was for “delayed-onset” neutrophilia. Although dramatic increases in plasma I ...
The Stimulatory Effect of Globular Adiponectin on Insulin
The Stimulatory Effect of Globular Adiponectin on Insulin

... muscle from lean versus obese individuals. Treatment with gAcrp30 (2.5 ␮g/ml) increased fatty acid oxidation in lean muscle (70%, P < 0.0001) and to a lesser extent in obese muscle (30%, P < 0.01). In the absence of insulin, gAcrp30 increased glucose uptake 37% in lean (P < 0.05) and 33% in obese mu ...
Centronuclear myopathy in mice lacking a novel muscle
Centronuclear myopathy in mice lacking a novel muscle

... Figure 3. MEF2-dependent muscle-specific transcription of Srpk3. (a) The structure of the mouse Srpk3 gene with schematics of the luciferase constructs and the results of luciferase assays are shown. Filled and open boxes indicate the exons for protein-coding and noncoding regions, respectively. MEF ...
GCSE PHYSICAL EDUCATION - The Marlborough School
GCSE PHYSICAL EDUCATION - The Marlborough School

... Smoking – Damages heart and lungs and raises blood pressure, increased risk of cancer, heart disease Reduces bodies ability to carry oxygen so performers suffer from fatigue and loss of breath more easily. Alcohol – Can cause damage to the liver and brain cells and increase likelihood of dehydration ...
Chapter 4 Exercise Metabolism
Chapter 4 Exercise Metabolism

... • Discuss several possible mechanisms for the sudden rise in blood-lactate during incremental exercise • List the factors that regulate fuel selection during different types of exercise © 2007 McGraw-Hill Higher Education. All rights reserved. ...
Chapter 9 Jeopardy Review
Chapter 9 Jeopardy Review

... ANSWER BACK TO GAME ...
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Myokine

A myokine is one of several hundred cytokines or other small proteins (~5–20 kDa) and proteoglycan peptides that are produced and released by muscle cells (myocytes) in response to muscular contractions. They have autocrine, paracrine and/or endocrine effects; their systemic effects occur at picomolar concentrations.Receptors for myokines are found on muscle, fat, liver, pancreas, bone, heart, immune, and brain cells. The location of these receptors explain the fact that myokines have multiple functions. Foremost, they are involved in exercise-associated metabolic changes, as well as in the metabolic changes following training adaptation. They also participate in tissue regeneration and repair, maintenance of healthy bodily functioning, immunomodulation; and cell signaling, expression and differentiation.
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