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The Origins of Variation
The Origins of Variation

... Origins of Genetic Variation 1) mutation - an alteration in DNA sequence, various types 2) intragenic recombination - results in entirely new associations of genes not present in either parental genome Two forms of intragenic recombination: a) crossing over, i.e., the exchange of genetic material b ...
Self-incompatibility
Self-incompatibility

... Commonly, the extra copies of chromosomes are not needed, and undergo rapid mutations and rearrangements. After several generations, the tetraploid is more like a diploid with lots of ‘junk’ DNA. ...
Chapter 13 Genetic Engineering
Chapter 13 Genetic Engineering

... Separating DNA • Gel Electrophoresis- DNA Fragments are placed in certain gel wells and an electric voltage is passed through them. • DNA molecules move toward the opposite end of the gel. • Smaller DNA fragments move faster through the gel. ...
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Slide 1

... Modified Organisms; also called transgenic organisms; contain recombinant DNA ...
Genetic Engineering
Genetic Engineering

... 1. Isolate the foreign DNA by using _____restriction enzymes___ that cleave (cut) the donor DNA at very specific places 2. Vectors transfer the donor DNA into the host a. mechanical vectors = Carry DNA into a cell, micropipette or metal bullet b. biological vectors = virus or bacterial plasmid (____ ...
DNA Review Cards
DNA Review Cards

... Describe what occurs during a base pair substitution mutation. ...
Experience 2 Follow-up 1. Answer the following
Experience 2 Follow-up 1. Answer the following

... (red) dominant over r (orange). Gene D then determines pigment deposition, and therefore color presence or absence, with D (red or orange color) dominant over d (colorless). A red snake mates with a colorless snake. Their F1 offspring appear in the ratio of 1 red: 1 orange. Determine the genotypes o ...
Mutations - Choteau Schools
Mutations - Choteau Schools

... problems in the cells or the organism. At times, the problem is so severe that the organism does not survive. ...
Lecture 6 pdf - Institute for Behavioral Genetics
Lecture 6 pdf - Institute for Behavioral Genetics

... haplotype map haplotypes small DNA regions, each inherited intact (vary across human populations) proteome all proteins able to be synthesized by a genome ENCODE ENCyclopedia Of DNA Elements project ...
Study Questions – Chapter 1
Study Questions – Chapter 1

... “Environmental DNA damage may drive human mutation” by David Biello in Scientific American, May 2006. “How trivial DNA changes can hurt health: Small changes to DNA that were once considered innocuous enough to be ignored are proving to be important in human diseases, evolution and biotechnology” by ...
Gene Technology
Gene Technology

... – Suprisingly few genes for the large human genome – Most DNA is non-coding – does not code for a protein – Many genes found in humans are the same as in other species – All humans are almost genetically identical ...
Bio 101 Study Guide Lecture Exam 3
Bio 101 Study Guide Lecture Exam 3

... • What is the advantage of sexual reproduction from an evolutionary point of view? • Know the stages of the eukaryotic cell cycle o Interphase (G1, S, G2) o Mitosis (prophase, prometaphase, metaphase, anaphase, telophase) o Cytokinesis • What happens in each stage? • Be able to identify the stage of ...
MUTATIONS
MUTATIONS

... a few results can occur:  Negative effect – organism’s chance of survival decreases (Tay-Sachs disease, animal in wild born with two heads)  Neutral effect – organism’s chance of survival is not affected (human born with extra toe, gluten intolerance, birth marks, eye color)  Beneficial effect – ...
Genetic Exchange - Pennsylvania State University
Genetic Exchange - Pennsylvania State University

... • Hfr can initiate transfer via the rolling circle mechanism; typically transfer of the chromosome is incomplete; only a fragment gets incorporated. ...
DNA/RNA Worksheet TACGGCACCGTTAGGATT
DNA/RNA Worksheet TACGGCACCGTTAGGATT

... 19. Using the genetic code, please indicate whether the following DNA base pair substitutions would lead to a change in the amino acid sequence by writing YES or NO. A. ...
Notes Unit 4 Part 8
Notes Unit 4 Part 8

...  transgenic = referring to organisms that contain __________ from a different organism within its genome  If the plasmid is accepted, the foreign DNA will be replicated very fast as the bacteria multiply  having lots of specific genes allows for those gene’s products to be _________________ as we ...
CH-13 Sect 1
CH-13 Sect 1

... 15. Biologists use ____________________________ to cut DNA molecules at a specific sequence of nucleotides to make smaller fragments. 16. Circle the letter of the process by which DNA fragments are separated and analyzed. a. gel electrophoresis b. extraction c. transformation ...
DNA to Protein - Duplin County Schools
DNA to Protein - Duplin County Schools

... What is the first thing that you must drag to the DNA molecule? __________ What happens to the DNA molecule when you do that? ___________ What is the sequence of RNA nucleotides that you add to the DNA? ___________ What happens to the mRNA? ___________ What attaches to the mRNA first? ___________ Wh ...
Extranuclear Inheritance
Extranuclear Inheritance

... Extranuclear Inheritance The past couple of lectures, we’ve been exploring exceptions to Mendel’s principles of transmission inheritance. Scientists have observed inheritance patterns that do not fit either Mendelian principles or the extensions of Mendelian genetics. Now that DNA has been discover ...
chapter 19_updates
chapter 19_updates

... DNA at specific nucleotide sequences • Type II restriction enzyme: most useful enzyme • By adding methyl groups to the recognition sequence to protect itself from being digested by its own enzyme in bacteria ...
Biology Chapter 11-1
Biology Chapter 11-1

... Hybridization- A cross between dissimilar individuals. (usually between different, but related, species.) Ex. Mules and pigs Mutagens- substances in the environment, such as radiation and chemicals, that cause mutations. Genetic engineering- a form of manipulation that allows biologists to engineer ...
Analysis of Genomes
Analysis of Genomes

... iv. alternative splicing v. chemical modifications B. Repetitive DNA (>50% of human DNA) 1. transposon derived (~45%) 2. pseudogenes 3. SSRs (3%) 4. segmental duplications of 10 - 300kb pieces (5%) 5. repeates at centromeres, telomeres and other C. Types of gene organization 1. gene families - some ...
Name___________ Midterm Review 1. What is an organism? 2
Name___________ Midterm Review 1. What is an organism? 2

... 10. Genetic information is passed to offspring during 11. What molecule contains the cells hereditary information? 12. What is a gene? 13. New cells or organisms from asexual reproduction have information. 14. Name a unicellular organism that reproduces by asexual reproduction. 15. Define autotroph. ...
14-3: Human Molecular Genetics
14-3: Human Molecular Genetics

... Continue to search for genes in many ways Research groups around the world Analyzing the huge amount of information in the DNA sequence Looking for genes that may provide useful clues to some of the basic properties of life ...
Genetics Study Guide Answers
Genetics Study Guide Answers

... Recombination between linked genes comes about for what reason? A) Mutation on one homolog is different from that on the other homolog. B) Independent assortment sometimes fails because Mendel had not calculated appropriately. C) When genes are linked they always "travel" together at anaphase. D) C ...
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Mitochondrial DNA



Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP). Mitochondrial DNA is only a small portion of the DNA in a eukaryotic cell; most of the DNA can be found in the cell nucleus and, in plants, in the chloroplast.In humans, mitochondrial DNA can be assessed as the smallest chromosome coding for 37 genes and containing approximately 16,600 base pairs. Human mitochondrial DNA was the first significant part of the human genome to be sequenced. In most species, including humans, mtDNA is inherited solely from the mother.The DNA sequence of mtDNA has been determined from a large number of organisms and individuals (including some organisms that are extinct), and the comparison of those DNA sequences represents a mainstay of phylogenetics, in that it allows biologists to elucidate the evolutionary relationships among species. It also permits an examination of the relatedness of populations, and so has become important in anthropology and field biology.
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