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ppt
ppt

... the O-H group of alcohols act as both an H-bond donor (Lewis acid) and H-bond acceptor (Lewis base). Ethers are only H-bond acceptors (Lewis base) 16.4: Crown Ethers (Please read) ...
ch07 by Dr. Dina
ch07 by Dr. Dina

... In the E2 dehydration the first step is again protonation of the hydroxyl to yield the good leaving group water ...
INTRODUCTION - Open Access Repository of Indian Theses
INTRODUCTION - Open Access Repository of Indian Theses

... 3. A Mild and Highly Efficient Synthesis of 3-Pyrrolyl-Indolinones and Pyrrolyl-Indeno[1,2-b]Quinoxalines using BiCl3 as a Catalyst An efficient synthesis of 3-pyrrolyl-indolinones and pyrrolyl-indeno[1,2-b] quinoxalines is described by the reaction of 4-hydroxyproline with isatin or indeno[1,2b]qui ...
Chapter 12 Packet
Chapter 12 Packet

... How many grams of HNO3 are needed to dissolve 11.45g of Cu? 21) The reaction of powdered aluminum and iron(II)oxide, 2Al(s) + Fe2O3(s)  Al2O3(s) + 2Fe(l) produces so much heat the iron that forms is molten. Because of this, railroads use the reaction to provide molten steel to weld steel rails toge ...
resonance effects - HCC Learning Web
resonance effects - HCC Learning Web

Microsoft Word - Open Access Repository of Indian Theses
Microsoft Word - Open Access Repository of Indian Theses

... Figure 4 The synthesis of furanoid sugar amino acids, starting materials for the peptide analogs of 1, was described in Scheme 1-3. The starting material for the synthesis of Fmoc-protected 2 was furan carboxylic acid 13, which was prepared from L-glutamic acid 12 in 66% yield, following the reporte ...
LAB - Building Organic Molecules
LAB - Building Organic Molecules

... Introduction: Organic molecules are the chemicals that sustain biological processes in all living things. These compounds are always made up of more than one type of element and must be synthesized by living organisms. What makes an organic molecule different from an inorganic molecule is that organ ...
Presentation11_108
Presentation11_108

... Smaller carboxylic acids (1 to 4 carbons) are soluble in water Whereas the solubility of bigger carboxylic acids decrease with size Aromatic acids are insoluble in water ...


... environmental and cheaper tools to improve a wide range of processes, which will reduce energy and raw material consumption, and to generate less wastes and toxic side-products. The principal drawbacks hindering a broader applicability of enzymes are the high production cost and the low yields [1]. ...
File - cpprashanths Chemistry
File - cpprashanths Chemistry

... A=A scale for measuring hydrogen ion concentration in a solution is called pH scale. PH is a number ( from 0 to 14 ) which indicates the acidic or basic nature of a solution. Higher the hydronium ion concentration lower is the pH value. .pH of neutral solution =7 .pH of acidic solution =less than 7 ...
Chapter 11: Alcohols and Ethers
Chapter 11: Alcohols and Ethers

Pd presentation
Pd presentation

Solvent free permanganate oxidations
Solvent free permanganate oxidations

... may make it the approach of choice. When the a-carbons are tertiary, the product is a dione, formed presumably by dehydration of the corresponding diol as in Scheme 6. Addition of alumina to the solid support did not improve the yields of these reactions. Arenes are converted into the corresponding ...
Full Article-PDF - UNC
Full Article-PDF - UNC

... protecting groups. While a variety of useful hydroxyl protecting groups are available, l, 2 occasionally, a situation arises which cannot be resolved by existing protecting group technology. During the course of recent efforts directed toward the synthesis of the magellanane alkaloids, the intramole ...


... questions regarding the class materials or you are asked any questions by the Instructor. Private talking in the class will hurt your understanding and also will hurt others. No sleeping in the class room allowed Objectives of the course: The principal objectives of this course is to get familiar wi ...
Structural Effects on Acidity
Structural Effects on Acidity

... Contribution due to intramolecular H-bonding is not significant in the o- nitrophenol, thus no apparent differences in ka when nitro group is placed in the o or p position. The greater acidity of the o and p nitrophenols as compared with the meta is attributed to the stronger effect of pi electron d ...
SN1 vs. SN2 Reactions - Master Organic Chemistry
SN1 vs. SN2 Reactions - Master Organic Chemistry

Section 3 d ethanol
Section 3 d ethanol

... more likely to be made by the fermentation method; in particular if the climate allows sugar cane to grow well and there is plenty of land available. Countries where land is scarce or not easy to cultivate and have oil reserves, hydration of ethane will be the favoured process. Use of ethanol: o as ...
Normality Primer
Normality Primer

... 10.  A 0.9932 g sample of limestone was titrated with 15.67 mL of 0.113 N HCl, what is the percent of  calcium carbonate in the sample?   11.  27.44 mL of 0.222 N Ba(OH)2 was required to neutralize all the benzoic acid (C6H5COOH) in a 1.224 g  sample of organic material.  What was the percent benzo ...
Chapter 18 - people.vcu.edu
Chapter 18 - people.vcu.edu

...  This reaction doesn’t happen to a large degree with most ketones  It happens a little more with aldehydes  Keq for formaldehyde is 40 Formation of Cyanohydrins o HCN is a toxic gas, so most often it is made in situ from excess NaCN and HCl. o Step one: cyanide ion attacks the carbonyl. ...
File - need help with revision notes?
File - need help with revision notes?

PHYSICAL CHEMISTRY/ORGANIC CHEMISTRY
PHYSICAL CHEMISTRY/ORGANIC CHEMISTRY

... Write the structural formula of the product of reaction between propanoic acid and ethanol in presence of an acid. Write the general reaction between a carboxylic acid and caustic soda, status the importance of this reaction in industry. ...
chemistry 232 elementary organic chemistry ii
chemistry 232 elementary organic chemistry ii

... Electrophilic Addition to Alkenes/Alkynes (Ch. 6 & 7, 11) Hydrohalogenation (i.e. addition of HCl) Halogenation (i.e. addition of Br2) Oxymercuration [addition of Hg(OAc)2] Hydroboration/Oxidation [addition of BH3 followed by NaOH/H2O2] Epoxidation (i.e. addition of mCPBA) Free-Radical Halogenation ...
Introduction - Bulgarian Chemical Communications
Introduction - Bulgarian Chemical Communications

... conformationally restricted transition states typical of cyclization and ring-opening reactions the situation becomes worse because the geometrical requirements become more specific and no longer correspond to those defining ES – the steric hindrance arising in acid catalyzed hydrolysis of open-chai ...
Alkanes CH4 + Cl2 → CH3Cl + HCl CH3CH3 + Cl2 → CH3CH2Cl +
Alkanes CH4 + Cl2 → CH3Cl + HCl CH3CH3 + Cl2 → CH3CH2Cl +

... atom goes on the atom with more H atoms to begin with. This will be studied more in a later unit, just remember it for now. It is Markovnikov’s rule. Substances that add to C=C bonds, such as H2, Br2, and HBr are termed electrophiles. Definition: An electrophile is an electron deficient species that ...
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Petasis reaction



The Petasis reaction (alternatively called the Petasis borono–Mannich (PBM) reaction) is the chemical reaction of an amine, aldehyde, and vinyl- or aryl-boronic acid to form substituted amines.Reported in 1993 by Nicos Petasis as a practical method towards the synthesis of a geometrically pure antifungal agent, naftifine, the Petasis reaction can be described as a variation of the Mannich reaction. Rather than generating an enolate to form the substituted amine product, in the Petasis reaction, the vinyl group of the organoboronic acid serves as the nucleophile. In comparison to other methods of generating allyl amines, the Petasis reaction tolerates a multifunctional scaffold, with a variety of amines and organoboronic acids as potential starting materials. Additionally, the reaction does not require anhydrous or inert conditions. As a mild, selective synthesis, the Petasis reaction is useful in generating α-amino acids, and is utilized in combinatorial chemistry and drug discovery.
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