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NMDA and stroke
NMDA and stroke

... • Simultaneous depolarization is required to remove Mg+ ion from blocking its pore • It is involved in cell death following stroke by its over activation due to excessive glutamate released by depolarized cells. • This causes Na+ and Ca2+ overload in the cells leading to swelling which attracts micr ...
PDF
PDF

... coronary artery spasm and hence the pathogenesis of ischemic heart diseases, since we reported that a decrease in coronary blood flow was induced by this lysophospholipid in an in vivo canine heart model [Cardiovasc. Res. 46 (2000) 119]. In this study, metabolism related to and cellular responses el ...
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11_Lecture_Presentation

... Plasma membranes ...
The Special Senses - Central High School
The Special Senses - Central High School

... Taste • From facial nerves to medulla oblongata, then thalamus, then sensory cortex • Afferent impulses of taste also stimulate reflexes which promote digestion ...
Lecture 8 Cell Signalling
Lecture 8 Cell Signalling

... Overview: Cellular Messaging • Cell-to-cell communication is essential for both multicellular and unicellular organisms • Biologists have discovered some universal mechanisms of cellular regulation • Cells most often communicate with each other via chemical signals • For example, the fight-or-fligh ...
Single TMS Receptors
Single TMS Receptors

... number of protein kinases which regulate many cellular functions. Ras with GTP bound activates Raf kinase which then activates MEK, MAP kinase kinase, which activates MAP kinase, MAPK. MAPK migrates from the cytosol to the nucleus where it phosphorylates transcription factors that induce the transcr ...
Cytokine receptor signaling through the Jak–Stat–Socs pathway in
Cytokine receptor signaling through the Jak–Stat–Socs pathway in

... levels of activated Stat4, which correlate with an increase in lung injury. In this case, it is thought to be due to excess IL-12R signaling, and that the hyperactivated Stat4 induces T cells toward the TH 1 type, potentially damaging the lung tissue (Di Stefano et al., 2004). Asthmatic patients als ...
Biochemistry Objectives 44
Biochemistry Objectives 44

... in the nephron receptor response to vasopressin. Can be caused by a problem in V2 receptor sensitivity to ADH, aquaporin-2 channel production, or any point in the pathways converging to aquaporin integration into the apical membrane. c. Secretion control at the following levels: a. Physiological: se ...
Immunology
Immunology

Common Characteristics of B and T Lymphocytes
Common Characteristics of B and T Lymphocytes

...  The B cell antigen receptor is a molecule of membrane-bound antibody.  The T cell antigen receptor, while not an antibody, shares some structural and functional properties with antibodies.  The T cell antigen receptor binds to protein antigens that have been digested into short peptides and are ...
Common Characteristics of B and T Lymphocytes
Common Characteristics of B and T Lymphocytes

... • The B cell antigen receptor is a molecule of membrane-bound antibody. • The T cell antigen receptor, while not an antibody, shares some structural and functional properties with antibodies. • The T cell antigen receptor binds to protein antigens that have been digested into short peptides and are ...
Cell Communication
Cell Communication

TLR4 signaling: negative regulation by degradation
TLR4 signaling: negative regulation by degradation

The elements of G protein-coupled receptor systems
The elements of G protein-coupled receptor systems

... Active α subunit can interact with and activate the next step in the signalling pathway ...
Do Plants Have Brains?
Do Plants Have Brains?

... First, plants have genes that are similar to those that specify components of animal nervous systems. Such components include receptors for glutamate, an amino acid that is one of the building blocks of proteins but that also functions as a neurotransmitter. Other components are neurotransmitter pat ...
fMRI: Biological Basis and Experiment Design
fMRI: Biological Basis and Experiment Design

Handout
Handout

... The mechanisms by which chloroplasts and bacteria divide are similar. Both utilize FtsZ proteins, which are self-assembling GTPases to form a dynamic ring of membrane-attached protofilaments and to recruitment of other division proteins and generate a contractile force that results in membrane const ...
Chapter 4 - Trimble County Schools
Chapter 4 - Trimble County Schools

... Hydrocarbons • Hydrocarbons  organic molecules consisting of only carbon and hydrogen can undergo reactions that release a large amount of energy ...
Photosynthesis & Respiration
Photosynthesis & Respiration

... make food—heterotrophs - must eat their food Ex: animals and most microorganisms ...
III. μ-Opioid receptors in the enteric nervous system
III. μ-Opioid receptors in the enteric nervous system

... which govern cellular responsiveness to agonist stimulation (3). Desensitization, which refers to the diminution of agonist effect after stimulation, is a mechanism to prevent uncontrolled response of the cell to stimuli, whereas resensitization represents the process by which cells become responsiv ...
the cell context influences rainbow trout gonadotropin receptors
the cell context influences rainbow trout gonadotropin receptors

... BACKGROUND: The presence of two distinct gonadotropin receptors (GtHRs) in a single fish species was confirmed by the molecular cloning of two different cDNAs in several fish species including trout. In mammals, GtHRs show little cross-activation (0.01–0.1%). In contrast, the bioactivity of fish gon ...
NEURONS COMMUNICATE WITH OTHER CELLS AT SYNAPSES
NEURONS COMMUNICATE WITH OTHER CELLS AT SYNAPSES

... • Sea hares (mollusks) pull their gills inside when certain parts of the body are touched: • They withdraw their gills more vigorously if they have previously been exposed to a noxious agent (sensitization). • The synapses between the sensory neurons and the motor neurons for gill withdrawal are fun ...
Name
Name

Dr. Vadim Gaponenko University of Illinois at Chicago
Dr. Vadim Gaponenko University of Illinois at Chicago

... Antagonist Tolerance G protein-coupled receptors (GPCRs) are among the most important therapeutic targets in the human body. Although initially effective, many drugs targeting GPCRs lose their potency after prolonged administration. This phenomenon is called drug tolerance. Tolerance is frequently c ...
Cell Communication Lecture ppt
Cell Communication Lecture ppt

... Cell-to-Cell Communications  Cell junctions directly connect the ...
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Purinergic signalling



Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.
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