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The Role of Autoantibodies in Diagnosis of Multiple Sclerosis
The Role of Autoantibodies in Diagnosis of Multiple Sclerosis

... In recent studies, the prevalence and titer of total, free, and bound cerebrospinal fluid anti–myelin basic protein antibodies as well as free/bound ratios were determined in four groups of patients with multiple sclerosis and three groups of controls. All patients with clinically active MS have inc ...
Post-Nasal Drip
Post-Nasal Drip

... for the elderly, who often have inadequate fluid intake. These patients should drink eight glasses of water a day, eliminate caffeine, and avoid diuretics (fluid pills) if possible. Mucous thinning agents such as guaifenesin or organic iodine may be employed. Guaifenesin (e.g. Humibid, Robitussin) r ...
Complex Structure Function Claims
Complex Structure Function Claims

... hands-on experience as a practitioner in the field of integrative medicine, he spent eight years working as a medical consultant for two companies in the dietary supplement industry, including four years as an executive with Nordic Naturals, in charge of clinical research. He previously served as Te ...
mitral valve disease : advances in catheter interventions
mitral valve disease : advances in catheter interventions

... In general, all patients with MS should undergo antibiotic prophylaxis against infective endocarditis for those procedures known to cause bacteremia. Diuretics are useful for treating mild symptoms. B blockers attenuate the increases in heart rate especially during exertion and optimise diastolic fi ...
An Integrated Framework for Cardiac Sounds Diagnosis
An Integrated Framework for Cardiac Sounds Diagnosis

... for the analysis of heart sound signals that compares a large number of different previous analysis methods and evaluated the contribution of each analytical stage. ...
Chronic Inflammation
Chronic Inflammation

... mediated by IgE and of parasitic infections. Like neutrophils, they use adhesion molecules and chemotactic agents (derived from mast cells, lymphocytes, or macrophages) to exit the blood. Eosinophils are phagocytic and undergo activation. Their granules contain major basic protein (MBP), a highly ca ...
Misuse of Antibiotics
Misuse of Antibiotics

... No. An antibiotic will not help. A runny nose is a common symptom of a chest cold or acute bronchitis. A runny nose may begin with clear drainage then turn to yellow or green drainage. Color changes in nasal mucous are a good sign that your body is fighting the virus. If a runny nose is not getting ...
Palpitations
Palpitations

... If your palpitations are caused by an over-awareness of the heart’s normal activity, you may just need reassurance that your heart rhythm is OK or that any palpitations you do have are harmless. In other cases, it may be worth avoiding ‘triggers’ such as coffee, alcohol and certain ‘overthe-counter’ ...
VAD / ECMO Complications
VAD / ECMO Complications

... 4 Mehta H, Eisen HJ, Cleveland JC Jr. (2015). Indications and complications for VA-ECMO for cardiac failure. http://www.acc.org/latest-in-cardiology/articles/2015/07/14/09/27/indications-and-complications-for-va-ecmo-for-cardiac-failure ...
Prevention of Heart Failure in Patients in the Heart
Prevention of Heart Failure in Patients in the Heart

... world in the next 2 decades4,5 as the levels of obesity, diabetes, and hypertension increase. In addition, more patients are surviving acute myocardial infarction but with damaged hearts, and life expectancy is predicted to increase.4 Therefore, the individual, community, health care, and economic b ...
Heart valve disease - British Heart Foundation
Heart valve disease - British Heart Foundation

... making it difficult for the valve to open. Also, infection of the valve (endocarditis) can cause damage to the leaflets (see pages 15 and 45). If it is possible, the mitral valve is usually repaired, but otherwise it is replaced. The tendons that hold the valve in place can also be affected, leading ...
Heart valve disease - British Heart Foundation
Heart valve disease - British Heart Foundation

... making it difficult for the valve to open. Also, infection of the valve (endocarditis) can cause damage to the leaflets (see pages 15 and 45). If it is possible, the mitral valve is usually repaired, but otherwise it is replaced. The tendons that hold the valve in place can also be affected, leading ...
Differentiation of myoendocrine cardiac cells from presumptive heart
Differentiation of myoendocrine cardiac cells from presumptive heart

... The heart of mammals and submammals contains a family of regulatory peptides with potent natriuretic, diuretic and vasorelaxant properties. Atrial natriuretic peptides (ANPs) are present in secretory granules of cardiocytes located mainly in the atrium of the rat heart (De Bold et al., 1981). The at ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)

... sufficiently comprehensive and effective if antimicrobial agent chosen has a wide spectrum of action8. The use of antibacterial prophylaxis of postoperative infection is firmly established within clean contaminated procedures. For clean procedures, prophylaxis has traditionally been reversed for ope ...
Purulent pericarditis and pneumonia caused by Streptococcus equi
Purulent pericarditis and pneumonia caused by Streptococcus equi

... equi subsp. equi are extremely rare (Waller et al., 2011). Streptococcus equi subsp. zooepidemicus, however, has a much wider host range, and is found in various domestic mammals, including horses, cattle, pigs, sheep, cats and dogs. It typically causes mastitis in cows, respiratory infections or in ...
Lecture 2- Immune and Lymphatic System
Lecture 2- Immune and Lymphatic System

... make them more easily destroyed by phagocytes or complement proteins. Cell-mediated immunity on the other hand directly destroys pathogens by either killing them or releasing chemicals which active inflammation and other host defense mechanisms. These 2 forms of adaptive immunity are achieved throug ...
Advances-in-Wound-care-2007 - Rex Moulton
Advances-in-Wound-care-2007 - Rex Moulton

... • Traditional delivery required repeated applications due to binding with chlorine and proteins • New silver dressings allow for continued silver release in to the dressing - up to 7 days 17Demling ...
acute systemic inflammation
acute systemic inflammation

... assay [19]. A very sensitive bio-assay for HGF was developed, and this assay did not respond to IL-1, indicating that HGF had to be another cytokine. After cloning of cDNA, HGF was discovered to be identical with a new cytokine named interleukin-6 [20]. In many in vitro and in vivo studies that foll ...
PACEMAKER: An Insight Into the Artificial Heart Rhythm
PACEMAKER: An Insight Into the Artificial Heart Rhythm

... Elmqvist in the year 1958. Later in 1959 engineer Wilson Greatbatch and the cardiologist W.M Chardack developed first fully implantable pacemaker. Engineer Wilson Greatbatch while modeling an oscillator to record heart sounds negligently fitted a wrong value resistor in his circuit. The whole circui ...
prepare to provide your answer!
prepare to provide your answer!

... • Restrict NA+/H2O intake (and exercise caution reducing oral intake below 500 ml per 24 hours). • Review diuretic dosing. Higher bolus doses will be more effective than more frequent lower doses. Diuretic infusions (eg, furosemide 20-40 mg bolus then 5-20 mg/h) can be a useful strategy when other o ...
What is Post-Nasal Drip - Vinod K. Anand, MD, FACS
What is Post-Nasal Drip - Vinod K. Anand, MD, FACS

... causing the post-nasal drip or if some other condition is to blame. If medical treatment fails. the patient must then decide whether to undergo surgery in an attempt to relieve the problem. In some cases, no specific cause can be found for PND. When no correctable disease is present. attention is us ...
real heart valve operation in cardiovascular model with
real heart valve operation in cardiovascular model with

... Heart valves control the heart function; which is the responsible for blood distribution through the lungs and the body. Modeling valves' function may provide a tool for studying the heart's performance, as well as, it helps to represent some of the most common heart’s abnormalities such as mitral v ...
The role of autoantibodies in health and disease
The role of autoantibodies in health and disease

... directed against very well conserved public epitopes [6]. On the other hand, specific adaptive immune responses through high-affinity, class-switched IgG autoantibodies can cause tissue damage or malfunctions and induce autoimmune diseases, through binding to self-proteins [7–9]. IgM-NAA are produce ...
Etiologic Classification of Degenerative Mitral Valve Disease
Etiologic Classification of Degenerative Mitral Valve Disease

... mid 1960s, the syndrome was recognized to be of a degenerative rather than rheumatic etiology because myxoid degeneration was found on histolgical examination of explanted valves. The macroscopic features of the Barlow valve were described and included voluminous thickening of the leaflets, and elon ...
Three-Dimensional Transthoracic Echocardiography
Three-Dimensional Transthoracic Echocardiography

... Martin Goldman, MD ...
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Rheumatic fever



Rheumatic fever, also known as acute rheumatic fever (ARF), is an inflammatory disease that can involve the heart, joints, skin, and brain. The disease typically develops two to four weeks after a throat infection. Signs and symptoms include fever, multiple painful joints, involuntary muscle movements, and a characteristic but uncommon non itchy rash known as erythema marginatum. The heart is involved in about half of cases. Permanent damage to the heart valves, known as rheumatic heart disease (RHD), usually only occurs after multiple attacks but may occasionally occur after a single case of ARF. The damaged valves may result in heart failure. The abnormal valves also increase the risk of the person developing atrial fibrillation and infection of the valves.Acute rheumatic fever may occur following an infection of the throat by the bacteria Streptococcus pyogenes. If it is untreated ARF occurs in up to three percent of people. The underlying mechanism is believed to involve the production of antibodies against a person's own tissues. Some people due to their genetics are more likely to get the disease when exposed to the bacteria than others. Other risk factors include malnutrition and poverty. Diagnosis of ARF is often based on the presence of signs and symptoms in combination with evidence of a recent streptococcal infection.Treating people who have strep throat with antibiotics, such as penicillin, decreases their risk of getting ARF. This often involves testing people with sore throats for the infection, which may not be available in the developing world. Other preventative measures include improved sanitation. In those with ARF and RHD prolonged periods of antibiotics are sometimes recommended. Gradual return to normal activities may occur following an attack. Once RHD develops, treatment is more difficult. Occasionally valve replacement surgery or repair is required. Otherwise complications are treated as per normal.Acute rheumatic fever occurs in about 325,000 children each year and about 18 million people currently have rheumatic heart disease. Those who get ARF are most often between the ages of 5 and 14, with 20% of first-time attacks occurring in adults. The disease is most common in the developing world and among indigenous peoples in the developed world. In 2013 it resulted in 275,000 deaths down from 374,000 deaths in 1990. Most deaths occur in the developing world where as many as 12.5% of people affected may die each year. Descriptions of the condition are believed to date back to at least the 5th century BCE in the writings of Hippocrates. The disease is so named because its symptoms are similar to those of some rheumatic disorders.
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