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DNA
DNA

... • These beads pack together, forming nucleosomes. • These coil to make chromatin • When the chromatin (stringy DNA) coils it make a chromosome ...
molecular biology review sheet
molecular biology review sheet

... 16. What does DNA hold the information for making? Diagram the central dogma? 17. Name the two processes that have to occur to convert the sequence of DNA letters into a sequence of amino acids? Where does each of these processes occur? Which type of RNA solves the problem that exists because DNA ca ...
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Virtual Lab: DNA and Genes

... What are potential outcomes we discussed in class for a point mutation? ...
Satiable Curiosity - Journal of Genetic Genealogy
Satiable Curiosity - Journal of Genetic Genealogy

... estimating the length, but genetic genealogists could furnish them with cases where a gene conversion event occurred in one line of descent. Using a heterozygous sample and DYS385 as an anchor, sequencing could proceed in both directions until a few single nucleotide polymorphisms (SNPs) were encoun ...
Chapter 12 PowerPoint
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... require insight into genes, their messages, and the proteins produced from those messages, as well as the new tools of molecular biology. ...
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DNA - California State University, Stanislaus
DNA - California State University, Stanislaus

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Mutations in the CFTR protein

... causing promoter or splicing errors, or large deletions or insertions. Rather, single amino acid substitutions, insertions, and deletions were examined to find the exact area of the protein that is important for functionality. Using the protein structure, it is predicted that mutations in the NBFs a ...
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... Researches into the radiation genetics of drosophila, performed by N.V. TimofeevResovsky in 20-30’s, became the basis of modern radiation genetics. He pioneered in the detailed study of the dose dependence of genetic effects and in phenotype description of radiation-induced mutations. These experime ...
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... The discovery of epistatic interactions between gene products is one of the most powerful tools in genetics – it allows the assembly of individual genes into pathways – and understanding of pathways leads to an understanding of mechanism. MCB140 09-17-07 12 ...
ANTH 1 Examples of Study Guides
ANTH 1 Examples of Study Guides

... o melt DNA of, for example, humans and chimps and snip one strand into shorter fragments o mix human and chimp DNA fragments and let cool to form hybrid; complementary bases o join; non-complementary bases don’t join, producing a weaker molecule o heat hybrid DNA and see at what temperature it melts ...
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... http://quizlet.com/3969760/3-orbit-and-eyeball-flash-cards/ ...
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... • Stable, heritable changes in sequence of bases in DNA – point mutations most common • from alteration of single pairs of nucleotide ...
The Code of Life: Topic 3
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... • Mutation - any change in the DNA sequence • Causes of mutations: – Errors in DNA replication (permanent error; 1 in every 100,000,000 bases) – Mutagens • UV light • Radiation • Chemicals • There are 2 major categories of mutations: – Point mutations – Frameshift mutations ...
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... 51. What is the cell cycle? 52. What are the two major phases of the cell cycle? What happens in each of these phases? 53. What is cytokinesis? 54. What is apoptosis? Why would a cell perform apoptosis? 55. What is a chromosome? 56. What is a histone? 57. Why do your cells make chromosomes from chro ...
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DNA/Protein Synthesis Study Guide

... Explain why the one gene - one polypeptide hypothesis needed to be modified in the light of conditions such as sickle-cell anemia. ...
Francis Crick - WordPress.com
Francis Crick - WordPress.com

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Mutation



In biology, a mutation is a permanent change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from damage to DNA which is not repaired or to RNA genomes (typically caused by radiation or chemical mutagens), errors in the process of replication, or from the insertion or deletion of segments of DNA by mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity.Mutation can result in several different types of change in sequences. Mutations in genes can either have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in nongenic regions. One study on genetic variations between different species of Drosophila suggests that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70 percent of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or weakly beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.
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