Drug presentation 1 - EMS PROGRAMS ENTRY PAGE
... • Dosage/Route: 0.4 to 2.0 mg IV/IM, 2 to 2.5X ET up to 10 mg, 2 mg MAD ...
... • Dosage/Route: 0.4 to 2.0 mg IV/IM, 2 to 2.5X ET up to 10 mg, 2 mg MAD ...
Materials and Methods
... The concentrations of the prostacyclin mimetics used in this study was chosen to include a broad range of concentrations starting from clinically relevant doses to supra-clinical doses. Thus are the first 2 concentrations of iloprost and treprostinil, the first 3 concentrations of epoprostenol and t ...
... The concentrations of the prostacyclin mimetics used in this study was chosen to include a broad range of concentrations starting from clinically relevant doses to supra-clinical doses. Thus are the first 2 concentrations of iloprost and treprostinil, the first 3 concentrations of epoprostenol and t ...
(Agonist) of Nuclear Receptor
... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
Pharmacodynamics
... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
胆碱受体激动药
... • Hydration process is prolonged for 30 minutes to 6 hours • Hydration process is prolonged for hundreds of hours ...
... • Hydration process is prolonged for 30 minutes to 6 hours • Hydration process is prolonged for hundreds of hours ...
Psychomotor stimulants
... crystalline form, water soluble pure if not diluted snorted or i.v. Cocaine free base extract (volatile solvents) smoked Crack free base made with baking soda & ammonia crackles when heated ...
... crystalline form, water soluble pure if not diluted snorted or i.v. Cocaine free base extract (volatile solvents) smoked Crack free base made with baking soda & ammonia crackles when heated ...
Adrenoceptor Blocking Agents
... Phentolamine and Tolazoline (Imidazoline derivatives). Non-selective for alpha-1 and alpha2 receptors. Duration of several hours. They also activate histamine receptors (adverse effect). ...
... Phentolamine and Tolazoline (Imidazoline derivatives). Non-selective for alpha-1 and alpha2 receptors. Duration of several hours. They also activate histamine receptors (adverse effect). ...
A Comparative Study Between Palonosetron and Granisetron to
... nausea, 10 = worst nausea. A score of more than 5 was considered severe and a score of 4 or less was considered as minimal nausea. Nausea was defined as unpleasant sensation associated with awareness of the urge to vomit. Retching was defined as the laboured, spastic, rhythmic contraction of the res ...
... nausea, 10 = worst nausea. A score of more than 5 was considered severe and a score of 4 or less was considered as minimal nausea. Nausea was defined as unpleasant sensation associated with awareness of the urge to vomit. Retching was defined as the laboured, spastic, rhythmic contraction of the res ...
Dr Richard Stevenson
... Piperazines Cathinones Synthetic cannabinoids Isolated compounds Recreational problem identified in 2008/2009 Varying legal status ...
... Piperazines Cathinones Synthetic cannabinoids Isolated compounds Recreational problem identified in 2008/2009 Varying legal status ...
9.98 Neuropharmacology
... Reboexitine is a drug that specifically blocks NE uptake Cocaine blocks the transport of DA, NE and 5-HT 4. Modulation of metabolism Inside the terminal the transmitters are also catabolized by 2 enzymes: Catechol-O-methyltransferase (COMT) and monoamide oxidase (MAO) Degradation of catecholamines p ...
... Reboexitine is a drug that specifically blocks NE uptake Cocaine blocks the transport of DA, NE and 5-HT 4. Modulation of metabolism Inside the terminal the transmitters are also catabolized by 2 enzymes: Catechol-O-methyltransferase (COMT) and monoamide oxidase (MAO) Degradation of catecholamines p ...
Problem 71- Vomiting, anorexia, nausea
... Core Problem 71- Vomiting, anorexia, nausea 1. Direct stimulating effect on H1 receptors located on blood vessels in the inner ear. Gives rise to local vasodilation and increased permeability, which helps to reverse the problem of endolymphatic hydrops. 2. Powerful antagonist effects at H3 receptor ...
... Core Problem 71- Vomiting, anorexia, nausea 1. Direct stimulating effect on H1 receptors located on blood vessels in the inner ear. Gives rise to local vasodilation and increased permeability, which helps to reverse the problem of endolymphatic hydrops. 2. Powerful antagonist effects at H3 receptor ...
Physiological Psychology
... Ligand – a molecule that binds to another. A neurotransmitter is a ligand of its receptor. ...
... Ligand – a molecule that binds to another. A neurotransmitter is a ligand of its receptor. ...
Extracellular serotonin in the lateral hypothalamic area is increased
... experiments resulted in similar findings; 5-HIAA increased in dialysate collected from the preoptic area after ejaculation (Fumero et al., 1994; Mas et al., 1995). Because of detection limits, however, 5-HT itself was not measured in those experiments. Lateral regions of the hypothalamus may also be ...
... experiments resulted in similar findings; 5-HIAA increased in dialysate collected from the preoptic area after ejaculation (Fumero et al., 1994; Mas et al., 1995). Because of detection limits, however, 5-HT itself was not measured in those experiments. Lateral regions of the hypothalamus may also be ...
Lecture 14
... mood inappropriation, paranoia (persecution mania) and hallucinations (voices) and Negative symptoms: withdrawal from society, flattened emotional responses, defect in selective attention (can’t distinguish between important and insignificant) Affects up to 1% of population, high suicide rate (10%) ...
... mood inappropriation, paranoia (persecution mania) and hallucinations (voices) and Negative symptoms: withdrawal from society, flattened emotional responses, defect in selective attention (can’t distinguish between important and insignificant) Affects up to 1% of population, high suicide rate (10%) ...
classical vs. neuropeptides
... 2. Autoreceptor: refers to transmitter receptors, on or near presynaptic terminals, which are sensitive to the transmitter(s) released by the terminal itself •Classification by transduction mechanism 1. Ligand-gated channels: - either excitatory or inhibitory actions - rapid action & rapidly reversi ...
... 2. Autoreceptor: refers to transmitter receptors, on or near presynaptic terminals, which are sensitive to the transmitter(s) released by the terminal itself •Classification by transduction mechanism 1. Ligand-gated channels: - either excitatory or inhibitory actions - rapid action & rapidly reversi ...
Bi-202-Lester-PsychiatricDrugs
... 1. “The mood-elevating effects of fluoxetine [Prozac] are not evident after initial exposure to the drug but require its continued use for several weeks. This delayed effect suggests that it is not the inhibition of serotonin transporters per se, but some adaptation to sustained increases in seroton ...
... 1. “The mood-elevating effects of fluoxetine [Prozac] are not evident after initial exposure to the drug but require its continued use for several weeks. This delayed effect suggests that it is not the inhibition of serotonin transporters per se, but some adaptation to sustained increases in seroton ...
CNSDrugs - shabeelpn
... – Loss of contact with reality & disorganized thoughts – Probable cause: increased dopamine release – Tx. Aimed at decreasing dopamine activity Two Chemical Classes: ...
... – Loss of contact with reality & disorganized thoughts – Probable cause: increased dopamine release – Tx. Aimed at decreasing dopamine activity Two Chemical Classes: ...
Mechanisms of drug action
... alpha receptor blocker. In a condition where there is a tumor of the adrenal gland which releases adrenaline(pheochomocytoma), this drug is given during surgery The reason is that during surgery, high amounts of adrenaline is released to the circulation ...
... alpha receptor blocker. In a condition where there is a tumor of the adrenal gland which releases adrenaline(pheochomocytoma), this drug is given during surgery The reason is that during surgery, high amounts of adrenaline is released to the circulation ...
Pharmacodynamics
... Has little clinical significance for a given therapeutic effect A more potent of two drugs is not clinically superior Low potency is a disadvantage only if the dose is so large that it is awkward to administer ...
... Has little clinical significance for a given therapeutic effect A more potent of two drugs is not clinically superior Low potency is a disadvantage only if the dose is so large that it is awkward to administer ...
Adrenoceptor Antagonist Drugs
... • Some have a higher affinity for β 1 than for β 2 receptors. • Since none of the clinically available β receptor antagonists are absolutely specific for β 1 receptors, the selectivity is dose-related; it tends to diminish at higher drug concentrations. • Other major differences among β antagonists ...
... • Some have a higher affinity for β 1 than for β 2 receptors. • Since none of the clinically available β receptor antagonists are absolutely specific for β 1 receptors, the selectivity is dose-related; it tends to diminish at higher drug concentrations. • Other major differences among β antagonists ...
Atypical Antipsychotic Drugs: Clozapine, olanzapine
... These are also called as major tranquillizers or neuroleptics. These are the drugs, which are used to treat psychosis, including schizophrenia and mania caused by bipolar disorder. They can also be used to treat severe depression and severe anxiety. A drug may be classified by the chemical type of t ...
... These are also called as major tranquillizers or neuroleptics. These are the drugs, which are used to treat psychosis, including schizophrenia and mania caused by bipolar disorder. They can also be used to treat severe depression and severe anxiety. A drug may be classified by the chemical type of t ...
β 3 - Faculty
... Brunton L L, Blumenthal D K, Murri N, Dandan R H, Knollmann B C. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11th ed. New York: McGrawHill, 2005. Carpéné, C., Galitzky, J., Fontana, E., Atgié, C., Lafontan, M., & Berlan, M. (1999). Selective activation of β3-adrenoceptors by octopa ...
... Brunton L L, Blumenthal D K, Murri N, Dandan R H, Knollmann B C. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11th ed. New York: McGrawHill, 2005. Carpéné, C., Galitzky, J., Fontana, E., Atgié, C., Lafontan, M., & Berlan, M. (1999). Selective activation of β3-adrenoceptors by octopa ...
Noradrenergic Transmission
... Systemic timolol may be absorbed from the eye to cause serious adverse effects on the heart & airways. Topical timolol may interact with orally administered verapamil & increase the risk of heart block. ...
... Systemic timolol may be absorbed from the eye to cause serious adverse effects on the heart & airways. Topical timolol may interact with orally administered verapamil & increase the risk of heart block. ...
5-HT3 antagonist
The 5-HT3 antagonists, informally known as ""setrons"", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain.With the notable exception of alosetron and cilansetron, which are used in the treatment of irritable bowel syndrome, all 5-HT3 antagonists are antiemetics, used in the prevention and treatment of nausea and vomiting. They are particularly effective in controlling the nausea and vomiting produced by cancer chemotherapy and are considered the gold standard for this purpose.The 5-HT3 antagonists may be identified by the suffix –setron, and are classified under code A04AA of the WHO's Anatomical Therapeutic Chemical Classification System.