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BASIC GENETICS REVIEW Genetics study of ________________________ Father of genetics Gregor Mendel ____________ born in 1822. high school ___________________. studied ________________________ plants. flowers have _________________. produce _________________. fertilization: __________________________________ peas are _________________. true-breeds: ___________________________ ________________: fertilized one plant with _____ from another. hybrids: ________________of crosses between _________ with _________________ true-bred __________ X true-bred ___________ hybrid offspring = _____ Trait ___________________ varies betw/ individuals. Heritable trait trait that __________________________. What did Mendel conclude? _____________________ are passed from generation to generation. __________: chemical factors that determine traits alleles: ______________________. e.g. gene for _______________________ Principle of dominance some alleles are ____________________________. dominant allele: ___________________________. recessive allele: ____________________________ e.g. trait = __________ tt = __________ Tt or TT = ____________ What did Mendel know? What did Mendel do? What did Mendel do next? crossed __________________________ recessive trait ______________. recessive trait ______________ Law of Segregation ____________________________ (sex cells) _________ (during meiosis). SO________________ during fertilization Genetics and Probability Probability ___________________________________. ___________________: heads = ½ each coin toss. Genetics? probability can be __________________________________. predictions are __________________ larger sample sizes _____________________. Punnett Square used to _______________________________________. Vocabulary genotype: _____________: write out alleles:“3Tt: 1tt” phenotype: __________________: “3 tall: 1 short” homozygous: _______________________________: TT or tt heterozygous: _______________________________: Tt Monohybrid cross example cross _________________________________ Offspring ____________: ¼ ______________________ 2/4 ______________________ ¼ _____________________ offspring ____________: ______________ Dihybrid cross Example cross _______________________________ dominant: __________________ recessive: ___________________ Parents (P) Filial (F1) ________ (round/yellow) X _______(wrinkled/green) offspring: _______ (hybrid) 2nd generation (F2) cross 2 F1 plants ______________ possible gametes (FOIL): _______________ offspring genotypes: _______________________ offspring phenotypes: _______________________ Principle of Independent Assortment ______________________________ during formation of gametes. creates ______________ in offspring. Summary of Mendel’s Principles 1. Inheritance ___________________________________________. 2. Alleles of genes can be ____________________________. 3. Somatic cells have ______________________________________. 4. Genes ________________________________________________. OTHER PATTERNS OF INHERITANCE It’s not always so simple…… Incomplete Dominance no allele is _________________. ___________________________________ phenotypes. Example red carnation X white carnation = ___________. P genotype: ___X___ F1 genotype: ______ phenotype: ______ Codominance _________________: both ________________ of offspring. red cow X white cow = roan cow (red and white). Example P genotype: ___X___ F1 genotype: ______ phenotype: ______ Multiple Alleles Example Blood type ______________ of a gene _________________________. ______________________________. alleles: ___________________________________ possible blood types Example P phenotype: ____X____ F1 genotype: ________ F1 phenotype: _______ genotype AA AO BB BO AB OO phenotype Sex linked genes Example Gene __________________________________ (more commonly X…the Y chromosome is tiny) 1. Colorblindness: _____________________________ possible genotypes: ____________________________ to be colorblind __________________________________ P genotype: ____X_____ F1 genotype: ____________ F1 phenotype: __________ 2. Hemophilia ________________________ possible genotypes:__________________________ P genotype: ____X_____ F1 genotype: ____________ F1 phenotype: __________ Polygenic Traits traits _______________________________. human _____________________. AABBCCDD X aabbccdd…..__________________. _____________________ possible Epigenetics (epi = above) traits _____________________________________. Genes are the ________. ENVIRONMENT ________________________. smoking, diet, stress, prenatal nutrition, trauma, etc. ____________ __________________________. _____________ on DNA or ________________. may be _________________________. can __________________. Mitosis Review Meiosis WHY? MEIOSIS _______________________________________daughter cells makes cells for ______________________________ occurs in _____________________ starts and results in ________________ ________________________ chromosomes _______________________________ ___________________________________________________ of chromosomes makes ________________ occurs in ___________________________________. ______________________________ results in _____________________ Chromosomes Crossing over Gene Linkage and Mapping different _____________________. humans: 2N = 46; 1N = ______ dog: 2N = 78; 1N = ______ shrimp: 2N = 254; 1N = _____ pineapple: 2N = 50; 1N = ______ homologous chromosomes ________ ____________________ of meiosis _____________________ genes can be ___________________________ on chromosomes. figured out with ______________. _________________________ chromosome. linked genes _______________________ chromosomes ______________________ linkage maps show ____________________ ___________________________________ cross-over frequencies: A-B=8% B-C=10% C-A=2%