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Digestive System A brief tour 1 Functions Ingestion Propulsion Digestion – Mechanical – Chemical Absorption Defecation 2 Anatomy Alimentary canal Accessory organs 3 Alimentary Canal Structure Propulsion: Peristalsis Four tunics 4 Alimentary Canal Oral cavity – Mechanical digestion: teeth, tongue, saliva – Chemical digestion: salivary amylases Pharynx Esophagus – Esophageal sphincter 5 Alimentary Canal Stomach – Mechanical digestion – Chemical digestion: proteases – Gastric juice: HCl, HCl, pepsinogens, pepsinogens, mucous 6 Alimentary Canal Small intestine – Digestion & absorption! – Pyloric sphincter – Divisions 7 Alimentary Canal Small intestine – Absorption Circular folds Villi & microvilli Lacteals Peyer’ Peyer’s patches 8 Alimentary Canal Small intestine – Chemical digestion Brush border enzymes Pancreatic enzymes Bile 9 Alimentary Canal Large intestine – Water & vitamin absorption, defecation – Divisions Colon: ascending, transverse, descending, sigmoid Rectum Anal canal – Appendix 10 Accessory Organs Teeth & tongue Salivary glands – Salivary amylases 11 Accessory Organs Pancreas: Pancreatic enzymes – Pancreatic amylases – Proteases (trypsin (trypsin)) – Lipases – Nucleases 12 Accessory Organs Liver & gall bladder – Bile: Bile: fat emulsification – Liver: produces bile – Gall bladder: stores bile 13 Chemical digestion recap Carbohydrates (sugars, starches) – Digested by: amylases into monosaccharides – Digestion: Mouth (starches): salivary amylases Small intestine: – Pancreatic amylases (starches) – Brush border enzymes (sugars) – Absorption: Small intestine liver 14 Chemical digestion recap Proteins – Digested by: Proteases into amino acids – Digestion: Stomach (pepsin: large proteins) Small intestine (brush border enzymes, pancreatic proteases: small proteins) – Absorption: Small intestine liver 15 Chemical digestion recap Lipids – Digested by: Lipases into fatty acids, glycerols, glycerols, glycerine – Digestion: small intestine Emulsified by bile salts from liver/gall bladder Digested by pancreatic lipases – Absorption: intestine Lacteals T.D. Small intestine liver Small 16 Chemical digestion recap Nucleic acids – Digested by: Nucleases into nucleotides – Digestion: small intestine Digested by pancreatic nucleases – Absorption: Small intestine liver 17