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Nursing Care and Interventions in Managing Chronic Renal Failure Keith Rischer RN, MA, CEN 1 Todays Objectives…       Review the pathophysiology and causes of chronic renal failure (CRF). Contrast lab findings and physiologic changes associated with acute vs. chronic renal failure. Identify relevant nursing diagnosis statements and prioritize nursing care for clients with CRF including dietary modifications. Compare and contrast the following treatment modalities: peritoneal dialysis, hemodialysis, and continuous renal replacement therapies. Identify nursing care priorities with hemodialysis and peritoneal dialysis. Prioritize teaching needs of clients with CRF. 2 Patho:Stages of Chronic Renal Failure  Diminished renal reserve  GFR ½ normal  Compensation w/healthy nephrons  Renal insufficiency  Nephrons destroyed…remaining adapt  BUN, creatinine, uric acid elevate  Priorities: fluid volume, diet, control of HTN,  End-stage renal disease  Severe fluid, acid-base imbalances  Dialysis needed or will die 3 Patho:Physiologic Changes • • • Kidney • Decreased GFR • Poor H2O excretion Metabolic – BUN and creatinine increased Electrolytes – Sodium- later stages sodium retention – Potassium increased – EKG changes – Kayexelate • • Acid-base balance: metabolic acidosis Calcium decreased and phosphorus increased 4 Patho:Physiologic Changes • • • Cardiac – Hypertension – Hyperlipidemia – Congestive heart failure – Uremic pericarditis Hematologic • anemia Gastrointestinal • • • Halitosis Stomatitis PUD 5 Patho:Physiologic Changes  Neurologic    Respiratory    pulmonary effusion SOB Urinary   lethargy Uremic encephalopathy proteinuria, oliguria, dilute Skin  dry, pallor, pruritus, ecchymosis 6 Drug Therapy        chart 75-3 p.1737 Cardioglycides  Digoxin/Lanoxin Calcium channel blockers Diuretics Vitamins and minerals  Folic Acid  Ferrous Sulfate Biologic response modifiers  Erthropoetin (Epogen) Phosphate binders  Aluminum hydroxide Stool softeners and laxatives 7 Excess Fluid Volume  Interventions:  Monitor I&O  Promote fluid balance  Daily weights  1 kg=1liter fluid  Assess for manifestations of volume excess:  Crackles in the bases of the lungs  Edema  Distended neck veins  Diuretics  Contraindicated w/ESRD 8 Decreased Cardiac Output  Interventions:  Control hypertension  calcium channel blockers  ACE inhibitors  alpha- and beta-adrenergic blockers  vasodilators.  Education: monitor blood pressure  client’s weight  Diet  Drug regimen  9 Potential for Pulmonary Edema  Interventions:  Assess for early signs of pulmonary edema  Restlessness/anxiety  Tachycardia  Tachypnea  oxygen saturation levels  Crackles in bases  Hypertension 10 Imbalanced Nutrition  Interventions:  Dietary evaluation for:  Protein  Fluid  Potassium  Sodium  Phosphorus  Vitamin supplementation  Iron  Water soluable vitamins  Calcium  Vitamin D 11 Risk for Infection  Interventions:  Meticulous skin care  Preventive skin care  Inspection of vascular access site for dialysis  Monitoring of vital signs for manifestations of infection 12 Risk for Injury  Interventions:  Drug therapy  Education prevent fall  Injury  pathologic fractures  bleeding  toxic effects of prescribed drugs  – Digoxin – Narcotics – Heparin or Coumadin 13 Fatigue  Interventions:  Assess for vitamin deficiency  Administer  vitamin and mineral supplements anemia  Give iron supplements as needed  Erythropoietin therapy  Buildup of urea 14 Anxiety  Interventions:  Health care team involvement  Client and family education  Continuity of care  Encouragement of client to ask questions and discuss fears about the diagnosis of renal failure 15 Indications for Dialysis Uremia  Persistent hyperkalemia  Uncompensated metabolic acidosis  Fluid volume excess unresponsive to diuretics  Uremic pericarditis  Uremic encephalopathy  16 Hemodialysis  Client selection  Irreversible renal failure  Expectation for rehab  Acceptance of regimen  Dialysis settings  Acute-hospital  Out patient centers 17 Hemodialysis:Patho   Diffusion Dialysate    Lytes and H2O Dialyzer Anticoagulation  Heparin to prevent blood clots in dialyzer or tubing 18 Vascular Access  Arteriovenous fistula, or arteriovenous graft for longterm permanent access  Hemodialysis catheter, dual or triple lumen, or arteriovenous shunt for temporary access  Precautions    Bruit & thrill BP restrictions Complications   Thrombosis CMS 19 Hemodialysis: Nursing Interventions   Predialysis care:  Medications to hold…why? Postdialysis care:  Monitor for complications such as hypotension, headache, nausea, malaise, vomiting, dizziness, muscle cramps.  Monitor vital signs and weight.  sepsis  Avoid invasive procedures 4 to 6 hours after dialysis.  Continually monitor for hemorrhage.  Assess for thrill  No BP or blood draws on arm 20 Peritoneal Dialysis  Phases     Inflow Dwell Drain Contraindications  history of abd surgeries  recurrent hernias  excessive obesity  preexisting vertebral disease  severe obstructive pulmonary disease 21 Complications of Peritoneal Dialysis       Peritonitis (cloudy outflow) Pain Exit site and tunnel infections Poor dialysate flow Dialysate leakage Monitor color of outflow  cloudy (peritonitis)  brown (bowel)  bloody (first week OK)  urine (bladder) 22 Nursing Care During Peritoneal Dialysis     Pre PD:  Vital signs pre and q 15-30” during  Weight  laboratory tests Continually monitor the client for:  respiratory distress  pain  discomfort Monitor prescribed dwell time and initiate outflow Observe outflow amount & pattern of fluid 23 Education Priorities Pathophysiology and manifestations  Complications  When to call the doctor  Keep record of all labs  Take medications and follow plan of care set out by case manager  Monitor weight, fatigue levels closely  24