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					Homeostasis and the Organization of the Animal Body Chapter 31 pages 604 - 618 Hierarchy of Structures    Tissues are composed of similar cells that perform a specific function Organs perform complex functions and include two or more interacting tissue types Organ systems consist of two or more interacting organs that function in a coordinated manner Cells, Tissues, Organs, Organ Systems How Is the Animal Body Organized?  Animal tissues are composed of similar cells that perform a specific function  There are four categories of animal tissues  Epithelial tissue  Connective tissue  Muscle tissue  Nerve tissue Epithelial Tissue  Covers the body, lines cavities, and forms glands  All body surfaces — skin, digestive, respiratory, and urinary tracts, and circulatory system  Epithelial tissue is sheets of cells firmly attached to one another by connections such as desmosomes and tight junctions  Attached to an underlying layer of fibrous proteins or basement membrane - provides support, flexibility, and strength  Cells are continuously lost and replaced Types of Epithelium  Simple epithelium is one cell thick and lines the respiratory, urinary, reproductive, and circulatory systems  Stratified epithelium is found in the skin and just inside body openings that are continuous with the skin (mouth and anus) and are continuously lost and replaced  Several cells thick and can withstand considerable wear and tear Epithelial Tissue flattened cells basement membrane (a) Lining of the lungs (simple epithelium) cilia mucus basement membrane mucusproducing cells (b) Lining of the trachea (simple epithelium) Skin - Epithelial Tissue dead cells flattened dying cells differentiating cells dividing cells basement membrane (c) Skin epidermis (stratified epithelium) Glands  Glands are cells or groups of cells specialized to secrete large quantities of substances outside the cell  Two categories  Exocrine glands secrete substances into a body cavity or onto the body surface, usually through a duct  Sweat glands, mammary glands, salivary glands, and glands that secrete digestive enzymes  Endocrine glands lack ducts, and release hormones into the extracellular fluid, diffuses into capillaries  Hormones are chemicals produced in small quantities and transported thru the bloodstream to regulate the activity of other cells Connective Tissues  Diverse structures and functions    Support and strengthen other tissues, binding the cells of other tissues into coherent structures, such as skin or muscle They consist of fluid containing proteins, especially collagen Three categories of connective tissue  Loose connective tissue  Dense connective tissue  Specialized connective tissue Loose Connective Tissue  The most abundant form of connective tissue, consisting of a thick fluid containing scattered cells that secrete protein  Flexible tissue connects, supports, and surrounds other tissue types, forming a framework for organs such as the liver Dense Connective Tissue  Packed with collagen fibers that provide flexibility and strength, but only in the direction in which the collagen fibers are arranged   Tendons, which connect bones to muscles Ligaments, which connect bones to bones Specialized connective tissues  Diverse functions and structures      Cartilage Bone Fat (adipose tissue) Blood Lymph Cartilage  Widely spaced cells surrounded by thick, nonliving matrix composed of collagen  It covers the ends of bones at joints, provides the supporting framework for the respiratory passages, supports the ear and nose, and forms shock-absorbing pads between the vertebrae  Flexible, but can break if bent too far Bone  Bone resembles cartilage, but its matrix is hardened by deposits of calcium phosphate  It forms in concentric rings around a central canal, which contain blood vessels Adipose  Adipose tissue is made up of fat cells that are modified for long-term energy storage  Can serve as insulation for animals living in a cold environment Blood and Lymph  Blood and lymph are specialized forms of connective tissue because they are composed largely of extracellular fluids in which proteins are suspended  The cellular portion of blood     Red blood cells transport oxygen White blood cells fight infection Platelets are cell fragments that aid in blood clotting The blood cells are suspended in a fluid called plasma Lymph  Lymph is fluid that has leaked out of blood capillaries, it enters the lymph vessels and is carried back to the circulatory system Muscle Tissue  Have the ability to contract  The long, thin cells of muscle tissue contract when stimulated and then relax when the stimulation stops  There are three types of muscle tissue  Skeletal muscle  Cardiac muscle  Smooth muscle Skeletal Muscle  Skeletal muscle is stimulated by the nervous system and is under voluntary, or conscious, control  Its main function is to move the skeleton Cardiac Muscle  Cardiac muscle spontaneously active, not under conscious control  Interconnected by gap junctions, through which electrical signals spread, stimulating cardiac muscles cells to contract in a coordinated fashion Smooth Muscle  Found throughout the body, in the walls of the digestive and respiratory tracts, uterus, bladder, and larger blood vessels  Produces slow, sustained, involuntary contractions that are stimulated by the nervous system, by stretch, or by hormones or other chemicals Nervous Tissue  Specialized to produce and conduct electrical signals  Brain, spinal cord, and nerve cells (neurons)   Neurons are specialized to generate electrical signals and conduct signals to other neurons, muscles, or glands Glial cells surround, support, insulate, and protect neurons How Is the Animal Body Organized?  Organs are formed from at least two types of tissues that function together; most consist of all four tissue types  Function as part of an organ system  The skin illustrates the properties of organs  Outer layer of epithelial cells underlain by connective tissue that contains a blood, nerve supply, muscle, and glandular structures derived from the epithelium Structural Components of Skin     Epidermis, or outer layer, is specialized stratified epithelial tissue Immediately beneath the epidermis lies a layer of loose connective tissue, the dermis, which contains blood vessels Specialized epithelial cells dip down from the epidermis into the dermis, forming hair follicles Below the dermis is a layer of adipose tissue Skin is an Organ hair shaft pore sebaceous gland capillary bed epidermis dead cell layer living epidermal cells dermis sensory nerve endings subdermal connective and adipose tissue hair follicle arterioles venules lymph vessels muscle (pulls hair upright) sweat gland Organ Systems  Two or more interacting organs, located in different regions of the body, that work together to perform a common function  Digestive system - in which the mouth, esophagus, stomach, intestines, liver and pancreas, all function together to convert food into nutrient molecules that can be absorbed into the bloodstream Homeostasis  Animal cells need a narrow range of conditions to survive  Homeostasis is the process by which an organism maintains its internal environment, within that narrow range How does it work?  The internal environment is maintained in a state of dynamic constancy  The internal environment is in a state of dynamic constancy  The body adjusts to ongoing internal and external changes to maintain constant conditions Examples of Regulated Conditions  Temperature  Water and salt concentrations  Glucose concentrations  pH (acid-base balance)  Oxygen and carbon dioxide concentrations Why is this Important?  Animal cells are constantly generating and using large quantities of ATP to sustain life processes  Continuous supplies of high-energy molecules and O2 are required to carry out the reactions that generate ATP  Energy production helps explain the importance of glucose and oxygen levels  Each of the reactions for producing ATP is catalyzed by a protein whose ability to function depends on its three-dimensional structure  This structure is maintained by hydrogen bonds, which can be disrupted if the environment is too hot, salty, acidic, or basic  The need to maintain these bonds helps explain the requirement for a narrow range of temperature, pH, and salt Animals vary in their homeostatic abilities  Birds and mammals are efficient at maintaining homeostasis for all the internal conditions listed above  Other animals have reduced or absent homeostasis for one or more aspects of their internal environment  For example, many marine invertebrates, including snails, crabs, and worms, cannot regulate the overall concentration of their bodily fluids Classification  Scientists classify animals according to their major source of body warmth  Endotherms generate heat through metabolic reactions - birds and mammals   Warm blooded Ectotherms derive body heat from the environment, and maintain it by occupying a constant environment or by behavioral activities reptiles, amphibians, fishes, and invertebrates  Cold blooded Warm-Blooded or Cold-Blooded? Regulation  Feedback systems regulate internal conditions  Homeostatic mechanisms that maintain internal constancy are called feedback systems  Two types  Negative feedback - counteracts the effects of changes in the internal environment to maintain homeostasis  Positive feedback, - drives rapid, self-limiting changes, such as those that occur when a mother gives birth Negative Feedback  Works by reversing the effect of a change     The most important feedback mechanism A change in the environment causes responses that “feed back” to counteract the change The overall result of negative feedback is a return to the original condition Three components    A sensor detects the current condition A control center compares that condition to the desired state, called the set point An effector produces an output that restores the desired condition Animation: Elements of a Feedback System Home temperature is regulated by negative feedback  Negative feedback systems that control body temperature are similar to those used to heat a home  The sensor is a thermometer, the control center is a thermostat, and the effector is the heater  The thermometer detects the room temperature and sends that information to the thermostat, where it is compared to the set point of the desired temperature  If the temperature is below the set point, the thermostat signals the heater to turn on and generate heat  The heater warms the room, restoring the temperature to the set point, causing the thermostat to turn off the heater Animation: Temperature Control in Your House Negative feedback maintains body temperature  The temperature control center is located in the hypothalamus, a part of the brain  Set point is between 97º- 99º F  Nerve endings act as temperature sensors and transmit information to the hypothalamus  If the body temperature falls below the set point, the hypothalamus activates effector mechanisms that raise body temperature   Shivering, blood vessel constriction, increased metabolic rate When body temperature is restored, the sensors signal the hypothalamus to switch off these actions Negative Feedback Maintains Homeostasis  The body’s temperature controls system can also act to reduce body temperature if rises above set point    Blood vessels leading to the skin to dilate, allowing warm blood to flow to the skin, where heat can be radiated into the air Sweat glands secrete fluid, cooling the body as it evaporates from the skin Fatigue and discomfort cause the body to slow down, so the body generates less heat Animation: The Control of Body Temperature Positive Feedback  Positive feedback enhances the effects of changes   A change produces a response that intensifies the initial change Positive feedback is relatively rare in biological systems, but occurs during childbirth and blood clotting Childbirth      Labor contractions force the baby’s head against the cervix at the base of the uterus, causing it to stretch and open Stretch-receptor neurons in the cervix signal the hypothalamus The hypothalamus releases oxytocin, a hormone which stimulates more and stronger contractions Stronger contractions cause the baby’s head to stretch the cervix even more, causing the release of more oxytocin Delivery of the baby relieves the pressure on the cervix, halting the positive feedback cycle Animation: The Control of Labor