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DJ Dorum 5/16/2013 RESPIRATORY SYSTEM Functions  Supply body with Oxygen  Removing excess Carbon Dioxide  Filter incoming air  Regulate temp of air & water content of air  Produce sounds  Smell  Blood pH Structures Upper Respiratory Tract  Nose  Nasal Cavity  Paranasal sinuses  Pharynx Lower Respiratory Tract  Larynx  Trachea  Bronchial Tree  Lungs Nose & Nasal Cavity Nasal Cavity Nose  Bones and cartilage support internally  Two nostrils  Hairs for guarding •Hollow space behind nose •Septum separates nostrils •Nasal conchae on each side •Many mucous cells •Heats incoming air •Mucus traps large particles •Cilia push particle towards pharynx Paranasal Sinuses  Air-filled gaps  Reduce weight  Affect voice  Located:  Maxillary  Frontal  Ethmoid  Sphenoid Pharynx  Aka: Throat  Passage way for food and air  3 parts:  Nasopharynx  Oropharynx  Laryngopharynx Larynx  Moves air in & out of     trachea Prevents foreign intrusion of trachea Houses vocal cords Made of cartilage & muscles 3 portions of cartilage:  Thyroid  Cricoid  Epiglottic  2 folds:  Upper: False vocal  Lower: True vocal  Glottis opens during breathing  Epiglottis covers glottis during swallowing Trachea  A.k.a. windpipe  Anterior to esophagus  Splits into bronchi  About 20 C-shaped cartilage pieces in wall  Posterior made of smooth muscle  Used to prevent collapse  Cilia line inner wall  Helps with filtering Bronchial tree  Airways within lungs  Begin with primary bronchi  Branch into smaller bronchioles  Into terminal bronchioles  Respiratory bronchioles after  Alveolar ducts are smallest tubes  Ducts lead to Alveolar sacs  Sacs divided into Alveoli  Diffusion takes place here Lungs  Soft and spongy  Within Thoracic cavity  Serous membrane Viscera Pleura, turns into Parietal Pleura  Space between them is pleural cavity http://www.goldiesroom.org/Multimedia/Bio_Image s/13%20Human%20Other/01%20Respiratory%20Sy stem.jpg Mechanics Inspiration •Diaphragm contracts, pressure in cavity drops •Diaphragm relaxes, pressure in cavity rises •Attraction of water in lungs can cause collapse •Substance surfactant synthesized to prevent collapse Expiration •Forces come from elastic recoil of cavity •Pectoralis minor and sternocleidomastoid help both  Ventilation= breathing. Moving air in and out Lung Capacity  Respiratory cycle = one inspiration plus following     expiration Tidal volume: amount of air moving during normal inspiration/ expiration. Inspiratory reserve volume: Large breath in Expiratory reserve volume: Large breath out Residual volume: Amount of air after forced expiration Avg volumes: •Tidal: 500 ml •I.R: 3,000 ml •E.R:1,100 ml of expelled air •Residual: 1,200 ml Respiratory Center  Medulla Oblongata and Pons  Two special areas:  Rhythmicity in Medulla  Pneumotaxic in Pons http://www.physioweb.org/IMAG ES/resp_center.jpg Medullary Rhythmicity Area  Two neuron groups  dorsal respiratory group  ventral respiratory group  Dorsal controls inspiration  Impulses tell diaphragm to contract  Ventral used only during forceful breathing Pneumotaxic area  Continuosly emits bursts originating from dorsal group  Controls breathing rate  Strong pneumotaxic inhibition= faster breathing rate  Weak pneumotaxic inhibition= slower rate Insane in the Membrane! •Walls of alveoli and capillaries are simple squamos •Wall of capillaries and alveoli create respiratory membrane http://webs.ashlandctc.org/mflath/KEYRESPIRATOR YOBJECTIVES_files/image017.jpg Diffusion of gases  Gases diffuse into blood  Concentration proportional to partial pressure  Amount of pressure contributed by proportion  If capillary pressure is higher than alveolar, CO2 diffuses into lungs  If capillary pressure is lower than alveolar, O2 diffuses into bloodstream http://faculty.stcc.edu/AandP/AP/imagesAP2/respiration/alvexch.jpg Transport  Gases dissolve into Oxygen Transport  More O2 released if: plasma or blood  CO2 concentration rises compounds  pH rises  Temp increases  Most O2 transported by hemoglobin in red blood  O2 deficiency called cells hypoxia  Product of combination is  Hypoxia possible causes: oxyhemoglobin  Unstable compound  Quick to release into surrounding O2 deprived cells  Decreased arterial Po2  Lack of ability of blood to transport O2  Inadequate blood flow  Cyanide poisoning Transport Cont’d •Carbon Dioxide transported 3 forms: •Dissolved in Plasma (least amount transported) •Part of hemoglobin compound (mid amount) •Bicarbonate ion (highest amount) •Amount in plasma determined by partial pressure •CO2 binds to “globin” part of molecule •Does not compete with O2 for binding sites •Bonds form carbaminohemoglobin •CO2 reacts with water: CO2 + H2O -> H2CO3 •Occurs slowly in plasma •Diffuses into red blood cells •Cells have enzyme carbonic anhydrase X-factors of breathing  Inflation relfex regulates depth of breath  Prevents over inflation of lung  Chemosensitive areas sense CO2 and pH changes in spinal fluid  Rise in chemicals increases tidal volume and faster breathing rate  Drop in chemicals triggers opposite response  Carotid & Aortic bodies detect O2 levels  Found in Carotid arteries and Aorta  Low O2 levels trigger increased breathing rate  Hyperventilation increases capacity  Smoking  Physical fitness Works Cited  "Body Systems: Respiratory System - The Human Heart: An Online Exploration from The Franklin Institute, made possible by Unisys." The Franklin Institute - Home - 215.448.1200 . N.p., n.d. Web. 2 May 2013. <http://www.fi.edu/learn/heart/systems/respiration.html>.  "Hiccups - MayoClinic.com." Mayo Clinic. N.p., n.d. Web. 3 May 2013. <http://www.mayoclinic.com/health/hiccups/DS00975>.  "Inspiration and Expiration." STCC Faculty Webpages. N.p., n.d. Web. 2 May 2013. <http://faculty.stcc.edu/AandP/AP/AP2pages/Units21to23/respiration/inspir at.htm>.  "Lung Disease - American Lung Association." Homepage - American Lung Association. N.p., n.d. Web. 3 May 2013. <http://www.lung.org/lungdisease/?gclid=CNai74LP-bYCFWQ6Qgodvw0AYA>.  Shier, David. "Respiratory System." Hole's Essentials of Human Anatomy and Physiology. 1983. Reprint. Boston: McGraw Hill, 2006. 428-452. Print.