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Ten Leading Causes of Disability in the World Type of Disability Cost (in DALYs) Cumulative % of Cost Unipolar major depression 42,972 10.3 Tuberculosis 19,673 14.9 Road traffic accidents 19,625 19.6 Alcohol use 14,848 23.2 Self-inflicted injuries 14,645 26.7 Manic-depressive (bipolar) illness 13,189 29.8 War 13,134 32.9 Violence 12,955 36.0 Schizophrenia 12,542 39.0 Iron deficiency anemia 12,511 42.0 Note: DALYs=disability-adjusted life-years. Two Major Traditions in Psychiatry Biomedical Psychodynamic Purposes of Diagnosis in Psychiatry Simplify our thinking Facilitate communication Predict outcome Decide on treatment Aid search for etiology Overview DSM  Childhood  Mood Disorders Disorders  Anxiety Disorders  Delirium,  Somatoform Dementia Disorders  Substance Induced  Personality Disorders Disorders  Schizophrenia and Other Psychotic Disorders Overview DSM  Factitious  Eating Disorders Disorders  Sleep Disorders  Dissociative  Impulse-Control Disorders Disorders  Sexual and Gender  Adjustment Identity Disorders Disorders MENTAL STATUS EXAM  APPEARANCE provides many clues to patient’s mental state. Observe carefully. Look at type and condition of clothing, hygiene, apparent health, any mannerisms, unusual actions, signs of intoxication or withdrawal, signs of hallucinating.  PSYCHOMOTOR ACTIVITY: may be agitated, normal, slowed and provides clues to overall mental state. MENTAL STATUS EXAM  ATTITUDE: How the patient relates to the examiner provides important clues. Attitude may be summarized in one or several words such as guarded, suspicious, hostile, friendly, ingratiating, manipulative, seductive, cooperative, threatening, flattering…reflecting much about the patient’s ability to function and relate. MENTAL STATUS EXAM: SPEECH Evaluate tone, rate and volume of speech. Look for the rapid, pressured speech of mania, the slowed speech of the profoundly depressed person. Other important variations from normal are seen in anxiety and in intoxicated states. MENTAL STATUS EXAM: MOOD AND AFFECT Mood is the prevailing subjective emotional state, primarily how the patient says he/she feels. Affect is how the mood is expressed and refers primarily to the observable facial expression. MENTAL STATUS EXAM: DESCRIPTION OF MOOD  EUTHYMIC  HAPPY  SAD  EUPHORIC  IRRITABLE  ELATED  ANXIOUS  ANGRY  Often, the most clear and colorful means of describing mood is to use the patient’s own words MENTAL STATUS EXAM: ASSESSING AFFECT Look for how appropriate the affect is and whether it corresponds to the topic under discussion. A full range of emotional expression is normal. Note any incongruent between affect and topic at hand. Look for lability of affect.  Blunted or flat affect is static regardless of topic at hand.  In mood disorders the affect is confined to either mania or depression and does not have full range.  ASSESSMENT OF SUICIDE The interviewer must develop an estimate of suicide risk with each patient by determining: Extent of current suicidality Presence of risk factors for suicide Presence of psychiatric diagnosis associated with risk for suicide SUICIDALITY AT TIME OF INTERVIEW Passive wish to die versus wanting to kill self Extent of specific plan Does the person have the means? How lethal is the plan? Suicide note Arrangements made? ASSESS FOR SUICIDE RISK FACTORS History of violence Family history of suicide History of prior attempts Male Single, divorced or separated History of certain types of trauma IS PSYCHIATRIC DISORDER PRESENT THAT IS ASSOCIATED WITH SUICIDE?  MOOD DISORDER  SCHIZOPHRENIA  PANIC DISORDER  SUBSTANCE ABUSE OR DEPENDENCE  SOME TYPES OF PERSONALITY DISORDERS MENTAL STATUS EXAM: THOUGHT PRODUCTION A patient’s thinking is mostly assessed by observing their verbal communication and judging their level of interest in the world around them.  Poverty of thought is seen in schizophrenia and depression.  Racing thoughts or “flights of ideas” are seen in mania.  Thought blocking is an abrupt cessation of conversation, after which the person is unable to recall the topic.  MENTAL STATUS EXAM: THOUGHT PROCESS THE MANNER IN WHICH THOUGHTS ARE ASSOCIATED, THE TRAIN OF THOUGHT Normal is goal-directed with coherence Abnormal may manifest in different ways DISORDERS OF THOUGHT PROCESS  CIRCUMSTANTIALITY  TANGENTIALITY  LOOSE ASSOCIATIONS  VERBIGERATION  WORD SALAD  NEOLOGISMS  CLANG ASSOCIATIONS  ECHOLALIA DISORDERS OF THOUGHT CONTENT: PREOCCUPATION  PHOBIA: irrational fear or dread, results in avoidance behaviors and anxiety  OBSESSION: disturbing, intrusive thought  COMPULSION: irresistible urge to perform usually meaningless activity, often is ritualistic DISORDER OF THOUGHT CONTENT: DELUSIONS DELUSION = a fixed, false belief that does not have basis in reality, not a part of religion or culture. The patient holding a delusion cannot be talked out of it, even with evidence to the contrary. DELUSIONS  Mood congruent delusions: themes are consistent with depression, such as centered around sin, nihilism, poverty, decay or consistent with mania, such as delusions about holding special powers  Contrast these with MOOD INCONGRUENT DELUSIONS…. DELUSIONS THAT ARE NOT MOOD CONGRUENT  Delusions of reference: outside events refer to the self  Delusions of control: outside forces are controlling oneself in some way  Schneider’s first-rank symptoms of schizophrenia -- may also occur in psychotic mood disorders and delirium SCHNEIDERIAN FIRST RANK SYMPTOMS Thought insertion Thought withdrawal Thought broadcasting Passivity feelings Delusional perception Auditory hallucinations PERCEPTUAL DISTURBANCE Illusions are misperceptions of existing stimuli Hallucinations occur in the absence of sensory stimuli Can involve any of the five senses but the type can provide clues as to diagnosis -- hallucinations are a symptom only HALLUCINATIONS  AUDITORY: seen in psychotic disorders such as schizophrenia, mania, psychotic depression  VISUAL: seen in medical, toxic disorders  TACTILE: substance-withdrawal delirium  OLEFACTORY AND GUSTATORY: seen as prodrome of complex partial seizure COGNITIVE FUNCTIONING Level of consciousness varies from lethargy to various levels of alertness Orientation -- check for this to person, place, time, situation Concentration/attention -- test by serial 7’s or serial 3’s MENTAL STATUS EXAM: MEMORY ASSESSMENT SIMPLE MEMORY TESTS CAN ASSESS RETROGRADE AND ANTEROGRADE MEMORY FUNCTION  Remote memory is for events in the distant past, often the last memory system affected in dementia  Recent memory is for the last few months  Immediate recall requires attention more than memory  Short-term memory is tested with remembering three objects immediately and after 5 minutes  MENTAL STATUS EXAM  Make a estimate of the patient’s level of intelligence  Insight -- how aware is the person of their situation  Judgment -- how able is the person to stay out of harm, provide for self, handle finances  History and interview should provide ample opportunity to assess CONDUCT OF THE MENTAL STATUS EXAMINATION  In open-ended, unstructured interviewing, assess appearance, orientation, level of consciousness, behavior, attitude, speech, thought form and content, affect.  Direct, focused questioning and exploration will be required to assess mood, suicidal and homicidal ideation, perceptual disturbance, cognitive functioning.