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					Assessment of the Endocrine System Endocrine system  Endocrine system (ES) – the nervous system and the interconnected network of glands  A key feature of all endocrine glands (EG) is the secretion of hormones  Hormones are biochemicals that exert their effect on target tissues  Target tissues (TT) – usually located some distance from the endocrine gland, with no direct physical connection between EG and TT Endocrine system  For this reason EG are called “ductless” glands and must use circulatory system to transport secreted hormones to the TT  EG include the following:       Pituitary gland Adrenal glands Thyroid gland Islet cells of the pancreas Parathyroid glands Gonads Endocrine system  The endocrine system works with the nervous system to regulate overall physiologic function – neuroendocrine regulation  The ES keeps the constant normal balance (homeostasis) of the organs and systems in response to environmental changes Endocrine system  Hormones:  steroid - hydrocortisone  peptide (protein) - insulin  amine – epinephrine  Negative feedback control mechanisms  In the healthy physiologic state, hormone concentration in the bloodstream is maintained at a relatively constant level  When the hormone concentration rises, further production of that hormone is inhibited  When the hormone concentration falls, the rate of production of that hormone increases Assessment. History  Demographic data  age and gender (some disorders are age related: hyperosmolar states, loss of ovarian function, decreased thyroid and parathyroid function; and gender related – sexual effects of hyperpituitarism and hypopituitarism) Assessment. History  Personal and family history  family history of obesity, grows or development difficulties, diabetes mellitus, infertility, or thyroid disorders  assess the client of the following: endocrine dysfunction; signs or symptoms that could indicate an endocrine disorder; hospitalisations  past and current medications (hydrocortisone, levothyroxine, oral contraceptives, antihypertensive drugs) Assessment. History  Diet history  Nutritional changes and GI tract disturbances may reflect a variety of endocrine problems (nausea, vomiting, abdominal pain)  Changes in food and fluid intake (diabetes insipidus, diabetes mellitus)  Rapid changes in weight without accompanying changes in diet (diabetes mellitus, thyroid disfunction) Assessment. History  Socioeconomic status  are the clients resources adequate to maintain the healthy diet, purchase needed medications  Current health problems  did the client’s symptoms occur gradually, or was the onset sudden?  has the client been treated for this problem in the past?  How have the current symptoms interfered with activities of daily living? Assessment. History  energy levels (changes in energy levels are associated with a number of endocrine problems: thyroid, adrenal glands)  elimination  urine amount and frequency. Does he or she urinate frequently in large amounts? Does the client wake during the night to urinate (nocturia), or does he or she experience pain on urinaton (dysuria)?  information about the frequency of bowel movements and their consistency and color Assessment. History  sex and reproduction. Women are asked about any changes in the menstrual cycle (increased flow, duration, frequency of menses; pain or excessive cramping; or a recent change in the regularity of menses). Men are asked whether they have experienced impotence. Both have to be asked about changes in libido or any fertility problems Assessment. History  Physical appearance. The client is asked about changes in the following:      hair texture and distribution facial contours voice quality body proportions secondary sexual characteristics Physical Assessment  Inspection  use a head-to-toe approach  observe a general client’s appearance, height, weight, fat distribution, muscle mass in relation to age  head: prominent forehead, jaw; round or puffy face; dull or flat face expression; exophtalmos (protrunding eyeballs and retracting upper lids) Physical Assessment  Inspection  lower half of the neck – visible enlargement of the thyroid gland (N – isthmus can be observed during the swallowing)  jugular vein dilation – can indicate fluid overload  skin – color, areas of hypo- or hyperpigmentation; fungal skin infections, slow wound healing, petechiae (adrenocortical hyperfunction); skin infections, foot ulcers, slow wound healing (diabetes mellitus) Physical Assessment  Vitiligo (patchy areas of depigmentation with increased pigmentation at the edges) – primary hypofunction of the adrenal glands. Most often occur on the face, neck and extremities. Mucous membranes can exhibit a large areas of pigmentation  Necessary to document the location, distribution, color, size of all skin discolorations and lesion  fingernails – malformation, thickness, or brittleness (thyroid gland difficulties) Physical Assessment  the extremities and the base of the spine are assessed for edema (disturbance in fluid and electrolyte balance)  trunk  abnormalities in chest size and simmetry  truncal obesity, supraclavicular fat pads and a “buffalo hump” – adrenocortical excess  secondary sexual characteristics – breasts of both men and women for size, symmetry, pigmentation and discharge Physical Assessment  Striae (usually reddish purple “stretch marks”) on the breasts or abdomen are often seen with adrenocortical excess  hair distribution – hirsutism (abnormal grows of body hair, especially on the face, chest, and the linea alba of the abdomen of women), excessive hair loss, or change in hair texture  genitalia (hypogonadism) Physical Assessment  Palpation  Thyroid gland (size, symmetry, general shape, presence of nodules or other irregularities)  the nurse palpates the thyroid gland standing either behind (may be easier) or in front of the client  offering the client sips of water to promote swallowing during the examination helps palpate the thyroid gland Physical Assessment  the client is asked to sit and to lower the chin  using the posterior approach, the thumbs of both hands are placed on the back of the clients neck, with the fingers curved around to the front of the neck on either side of the trachea  the client is asked to swallow, and the nurse locates the isthmus of the thyroid and feels it rising. The anterior surface of the thyroid lobe is also identified Physical Assessment  to examine the right lobe, the nurse:  turns the client’s head to the right  displaces the thyroid cartilage to the right with the fingers of the left hand  palpates the right lobe with the right hand  this procedure is reversed for examination of the left lobe Physical Assessment  Auscultation  the nurse auscultates the client’s chest to establish baseline vital signs and to determine irregularities in cardiac rate and rhythm  the nurse documents any difference in client’s blood pressure and pulse in the lying, standing, or sitting positions (orthostatic vital signs) – many endocrine disorders can cause dehydration and volume depletion Physical Assessment  Auscultation  if an enlarged thyroid gland is palpated, the area of enlargement is auscultaded for bruits (hypertrophy causes an increase in vascular flow) Diagnostic Assessment  Laboratory tests  Best practice for endocrine testing  explain the procedure to the client  emphasize the importance of taking a medication prescribed for the test on time. Tell the client to set an alarm if the medication is to be taken during the night  instruct the client to begin the urine collection (whether for 2, 4, 8, 12 or 24 hours) by emptying his or her bladder. Tell the client NOT to save the urine specimen that begins the collection. The timing for the urine collection begins after this specimen. To end the collection, the client empties his or her bladder at the end of the timed period and adds that urine to the collection Diagnostic Assessment  make sure that the preservative has been added to the collection container at the beginning of the collection, if necessary. Tell the client of its presence in the container Diagnostic Assessment  check your laboratory’s method of handling hormone test samples. Blood samples drawn for certain hormones (e.g., catecholamines) must be placed on ice and taken to the laboratory immediately  if you are drawing blood samples from a line, clear the IV line thoroughly. Do not use a double- or triple-lumen line to obtain samples; contamination or dilution from another port is possible Diagnostic Assessment     Stimulation/suppression tests Radioimmunoassay Urine tests Tests for glucose  Radiographic examinations  Other diagnostic tests (needle biopsy)