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					The Nervous System BY LYDIA CHANG, LAUREN LEE, AND DIANA ZHENG Evolution of the Nervous System  Porifera: no nervous system  Cnidaria: nerve net all throughout body—can react to stimuli from all        sides Platyhelminthes: cephalization; ganglia, eyespots, two main ventral nerve cords Rhynchocoela: dorsal nerve cord, two lateral nerve cords Nematoda: ring of nervous tissue around pharynx attached to dorsal and ventral nerve cords Annelida: pair of brain-like cerebral ganglia and subpharyngeal ganglion Mollusca: ranges from simple nervous system to relatively complex systems that rival those of mammals Arthropoda: cerebral ganglion (brain!); sense organs concentrated on head Echinodermata: decentralized nervous; no brain but have ganglia along radial nerves in some species; sensory neurons within podia Evolution of the Nervous System  Vertebrates: very centralized and cephalized; well-developed sensory organs; dorsal, hollow nerve cord (spinal cord)  Lampreys and hagfishes: no myelin sheath  Fish: enlarged cerebellum  Amphibians: growing importance of forebrain, but midbrain still important  Reptiles/Birds: many connections between thalamus and hemispheres  Birds: larger cerebellum  Mammals: brain completely dominated by cerebral hemispheres; large surface area; controlled mainly by cortex; large thalamus The Human Nervous System  Brain: about 2% human body mass        Neocortex: outer layer of brain Human cerebral cortex (aka pallium): flat sheets of cells in six layers Frontal lobe: reasoning, speech, motor cortex Parietal lobe: speech, taste, reading, somatosensory cortex Temporal lobe: hearing, smell, auditory Occipital lobe: sight Cerebellum: ballistic movements, balance, coordination, helps in learning and remembering motor skills From “Vertebrate Nervous System” The Brain, cont’d  Diencephalon: major integrating centers information, act as relay stations for info flow  Thalamus: main relay center for sensory information  Hypothalamus: maintains homeostasis  Brain stem: includes the pons, medulla oblongata  transfers info between peripheral and central nervous systems  helps coordinate large-scale body movements (e.g. running)  nerve crossing: right side of brain controls left side of body and vice versa  Midbrain/RAS (reticular activating system): centers for receiving and integrating several types of sensory info  Corpus callosum: connects brain hemispheres From Wikipedia Evolutionary Trends  More complex!  This system is necessary for complexity and sophisticated behaviors/responses to environment  Increases chance of survival: more complex NS = more complicated nerve connections, behaviors, movements  The nervous system controls all other body systems!! Except maybe skeletal Neurons  Neurons  Sensory neurons  Interneurons  Motor neurons How Neurons work  Resting potential: negative relative to the outside  Sodium-potassium pumps in the plasma membrane  Transport sodium out of the cell and potassium into it  Very few sodium channels  Net negative charge inside cell Action Potential  Depolarization  Rising phase of the action potential  Falling phase of the action potential  Undershoot: Potassium channels close to bring it back to the concentration needed to be at resting potential  refractory period Conduction of the Action Potential  Action potential: a “wave” from dendrite to axon  Speed is determined by axon diameter  Evolutionary trend: Because vertebrate axons have narrow diameters, vertebrates have adapted the myelin sheath to enable more efficient conduction  Nodes of Ranvier (nodes between gaps in myelin sheath) allows for saltatory conduction  current jumps from node to node Synapses  Electrical synapses: contain gap junctions to allow electrical currents to flow from one neuron to another  Chemical synapses (most synapses): neurotransmitter  Examples of neurotransmitters: acetylcholine, biogenic amines (serotonin) Disorders and Diseases  Cerebrovascular accident (stroke)  Parkinson's disease:  decreased stimulation of the motor cortex by the basal ganglia caused by the insufficient formation and action of dopamine  Multiple sclerosis: immune system damages the myelin  When myelin is lost, the axons can no longer effectively conduct signals Works Cited and Consulted  AP Bio book  http://faculty.washington.edu/chudler/nsdivide.html  http://parasitology.informatik.uni    wuerzburg.de/login/n/h/0941.html http://www.daviddarling.info/encyclopedia/V/vertebrat e_nervous_system.html http://infusion.allconet.org/webquest/PhylumMollusca. html http://www.mindcreators.com/Images/NB_Neuron.gif http://en.wikipedia.org/wiki/File:Neurons_big1.jpg
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            