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Bill Nye - Cell  http://www.youtube .com/watch?v=RU 5Ymc00S4w&play next=1&list=PLAC 1748A99AA7536A &feature=results_vi deo Discovery of Cells  Robert Hooke, 1665  Cells in Cork  Cellulae (little room) Life 1402: Principles of Biology Chapter 4: A Tour of the Cell Lecture Objectives:  Know the cell theory of life  Understand the difference between prokaryotic and eukaryotic cells  Appreciate the difference between an animal and plant cell  Understand the significance of cellular compartmentalization  Sketch the basic structure of a cell membrane and identify its components  Appreciate the basic functions of various organelles within the cell and how these structures work together to support the cell  Since the 1600s, scientists have made many discoveries about the cells of living things. Hooke – discovered and named cells while observing cork (1670)  Robert  Anton van Leeuwenhoek (1680?) • Dutch fabric merchant and amateur scientist • observed living cells; called some 'animalcules'  Matthias • • Schleiden (1838) German botanist discovered that plants are made of cells  Theodor • • Schwann (1839) German zoologist discovered that animals are made of cells  Rudolph • • Virchow (1855) German physician stated that all living cells come only from other living cells  These discoveries are summarized in the cell theory.  The    cell theory states: All living things are made up of cells. Cells are the basic units of structure and function in living things. New cells are produced from existing cells. Cell theory theory – the cell is the most fundamental and common unit of living organisms; therefore, the definition of life is the presence of cells. Cell Pro- vs. eukaryotic cells “before”  Eu – “true”  Karyote “kernel” or Nucleus  Prokaryote – no membrane bound nucleus  Eukaryote – true nucleus  pro- A Tour of the Cell  Cells are the basic unit of all living things.  Cells possess a plasma membrane, organelles and cytoplasm Cytoplasm – semifluid substance inside the cell membrane, between organelles Cell Size  Cell size and shape is related to function  Nerve cells can be 1 meter long  Ostrich eggs are the largest single cell  The largest animal and plant cells are 100 mm while the smallest cells are 10mm  Prokaryotic cells are between 2 and 8 mm Cell Size Limits  Surface Area : Volume Ratio limits cell size  A cell must absorb all nutrients and excrete all wastes through the membrane surrounding it  The more volume a cell has the more it must move across the membrane  As a cell grows the volume increases faster then the surface area (size of membrane) Prokaryotic Cells  Prokaryotic cells have no clearly defined nucleus, but do have a nucleoid region  The nucleoid region is a coiled loop of DNA, but isn’t contained in a membrane  Ribosomes are used to make proteins Prokaryotic Cells A bacterial cell wall surrounds the plasma membrane  Some prokaryotes have a sticky layer called a capsule surrounding the wall  Pili may attach the bacteria to a surface, while some use flagella for motility Eukaryotic Cells  Eukaryotic cells are divided into compartments or organelles  The nucleus is the most obvious structure in a eukaryotic cell Eukaryotic Cells  Most of the cells chemical activities or cellular metabolism are conducted inside the organelles  Plant cells contain some additional organelles and a cell wall Nucleus  The Nucleus is the genetic control center of a eukaryotic cell.  Nuclear DNA is in very long fibers called chromatin  Each fiber of chromatin is a chromosome  During cell division, chromatin condenses so it is visible Nucleus •The nuclear envelope is the membrane that surrounds the nucleus. It contains pores that control the flow of material. •The nucleolus is responsible for making ribosomes Endomembrane System  Organelles that are formed by interrelated membranes.  Endoplasmic Reticulum “Network within the Cell” Two types smooth and rough  Rough ER is covered with ribosomes and is used to produce membranes.  Rough ER is also responsible for making proteins that are to be secreted by the cell, such as antibodies. Golgi Apparatus  The Golgi apparatus receives molecules from the ER, sorts, packages and ships them to the proper destination. Lysosomes (lyse – break down, somebody) consist of digestive enzymes in a membranous sac. These are used to digest nutrient particles, bacteria (wbc’s) and recycle worn out organelles.  Lysosome Lysosomes  Tay-Sachs and Pompe’s diseases are both caused by a missing gene for an lysosomal enzyme making victims unable to break down certain molecules. Tay-Sach and Pompe’s Disease  http://www.youtube .com/watch?v=Seo PF74QSms  http://www.youtube .com/watch?v=BDl KFFpCnRo Mitochondria  Convert food into usable a form of Energy (ATP) for the cell.  Mitochondria are made up of two membranes. The space between the two membranes is the intermembrane space, while the second membrane contains the mitochondrial matrix. . Mitochondria  The folds in the inner membrane are cristae. They increase the surface area of the inner membrane.  Mitochondria have their own DNA and reproduce on their own resembling a prokaryotic cell. All of your mitochondria are inherited from your mother. Plant Cells  Being photosynthetic plants require a few more organelles, including vacuoles and chloroplasts as well as a cell wall. Vacuoles  Vacuoles are mainly used for water storage, but can also store starch or other nutrients. Vacuoles  By filling with water the central vacoule increases the cell’s volume putting pressure on the cell wall. This is called turgor pressure and helps to support plants. Plants wilt due to a loss of turgor pressure. Chloroplasts  Chloroplasts are the organelle of photosynthesis.  Chloroplasts are similar to mitochondria in that they have two membranes, but they also contain stacks of disks called grana where chlorophyll traps light energy. Chloroplasts  As in mitochondria, chloroplasts have their own DNA and reproduce on their own. Cilia and Flagella  These structures are used by cells mainly for movement.  Cilia are usually shorter and too numerous to count.  Flagella are usually longer and few in number. Cilia and Flagella  Trachea cells are lined with cilia that help move foreign objects and mucous out of the lungs.  Sperm cells have flagella to make them motile.
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            