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ADHD Etiology  8.4% of children  Boys>Girls  Deficit of catecholamines _____ & ______________________   Decreased threshold for stimuli (_________________) Delay in self-regulation (________________, ______________________) Clinical Manifestations DSM V Criteria  Inattentive  Hyperactivity for 6 months  Impulsivity for 6 months  Some symptoms present before age ___________  Present in 2 or more settings  Impairment in social, academic or occupational functioning  Not accounted by another Mental Illness Diagnosis  Family history  Birth history  G&D milestones  Sleeping & eating patterns  School performance  Social & environmental conditions  PE-R/O neurological cause Social Implications  Parents  Children Co-morbidities Therapy  Environmental  Behavior  Diet  Medications Medications-Stimulants      Increase synaptic levels of dopamine & norepinephrine 2-4 weeks to titrate dose for effect Long-acting Short-acting Chewable forms   Reduces interrupting, fidgeting, (hyperactive sx) Improves task completion & home relationships Medications - Stimulants         Adderall® (intermediateacting) Adderall XR® (long-acting) Concerta® (long-acting) Daytrana® (long-acting patch) Dexedrine® (short-acting) Dexedrine® Spansule® (intermediate-acting) Focalin® (short-acting) Focalin XR® (long-acting)        Metadate CD® (longacting) Metadate® ER (intermediate-acting) Methylin™ ER (intermediate-acting) Ritalin® (short-acting) Ritalin LA® (long-acting) Ritalin SR® (intermediateacting) Vyvanse® (long-acting) Medications-Stimulants  Adverse          Effects _________________ _________________ Headaches Abdominal discomfort ___________________ Irritability ___________________ Social withdrawal Lowers seizure threshold Medications-Nonstimulants  Norepinephrine reuptake inhibitor      Anti-depressants  atomoxetine (Strattera) - 1-2 X a day Less potential of substance abuse Risk for ______________ Biggest side effect – _____________________   Ideal for ADHD + depression not as effective as stimulants or Strattera at improving attention span and concentration. Tricyclic antidepressants: Pamelor™ (nortriptyline), Tofranil® (imipramine), and Norpramin® (desipramine)  Wellbutrin, Effexor, Monoamine oxidase inhibitors (MAOIs) Alpha Adrenergic Agonists  Extended-release meds - guanfacine (Intuniv) - clonidine (Kapvay) *used if no response to stimulants *used as adjunct for partial response to stimulants Future substance abuse  According to the National Institute of Drug Abuse, the answer is no.  "The studies conducted so far have found no differences in later substance use for children with ADHD who received treatment and those that did not. This suggests treatment with ADHD medication appears not to affect (either negatively or positively) an individual’s risk for developing a substance use disorder." (National Institute of Drug Abuse, 2014). Follow-up  How often should we follow-up and why?  https://youtu.be/z2hLa5kDRCA
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            