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7:1 Basic Structure of the Human Body  The normal function of the human body is compared to an organized machine  The machine malfunctions, disease occurs.  Anatomy: study of form and structure.  Physiology: study of why and how living organisms work.  Pathophysiology: study of how disease occurs and body’s response  Protoplasm – Makes up all living things. Cells  Microscopic Structures  Carry on all functions of life. Functions of Cells  Take in food and oxygen  Produce heat and energy  Move and adapt to environment  Eliminate wastes  Perform special functions  Reproduce to create identical cells Basic Parts of Cells  Cell membrane – outer protective covering of cell  Semipermeable  Cytoplasm – semifluid inside cell where all chemical reactions occur  Organelles – located in the cytoplasm and help cell to function Organelles  Nucleus – “brain” of cell, controls many cell activities, important in cell reproduction.  Nucleolus – Located in nucleus. Important in cell reproduction. Manufactures ribosomes which aid in synthesis (production) of protein  Chromatin – Located in nucleus, made of deoxyribonucleic acid (DNA) and protein. Chromatin condenses to form chromosomes during cell reproduction. Chromosomes carry genes which carry inherited characteristics. Organelles cont. Organelles, cont.  Centrosome – located in cytoplasm and near the nucleus. Contains two centrioles important in cell reproduction.  Mitochondria – located throughout cytoplasm, “furnace” or “Power House” of the cell. Produces adenosine triphosphate (ATP) which is the major energy source of the cell.  Golgi Apparatus – stack of membrane layers located in the cytoplasm. Produces, stores, and packages secretions for discharge from cell. Organelles of a cell, cont.  Endoplasmic Reticulum – located in cytoplasm. Allows for transport of materials in and out of the nucleus. Aids in synthesis and storage of proteins.  Lysosomes – Found throughout cytoplasm. Contains digestive enzymes that digest and destroy old cells, bacteria and foreign materials.  Pinocytic Vesicles – Pocket-like folds in cell membrane. Allow large molecules such as protein and fat to enter cell then folds closed to form vacuoles or bubbles in cytoplasm Cell Reproduction  Mitosis – Reproduce by dividing into two identical cells, asexual reproduction.  Meiosis – Reproduction of sex cells (gametes- eggs & sperm). Produces ovum and sperm. Mitosis and Meiosis Tissues  Cells contain same basic parts but vary in shape, size, and special function.  Cells of same type join together for common purpose to form tissue.  Tissue Fluid –water with various dissolved substances which makes up 60% - 99% of tissue  Dehydration – Insufficient amount of tissue fluid  Edema – Excess amount of tissue fluid; results in swelling of tissue Types of Tissue  Epithelial – Covers surface of body, main tissue in skin, also forms lining of intestines, respiratory, and urinary tracts; forms body glands Types of Tissue, Connective  Connective – Supportive fabric of organs and other body parts  Types of Connective Tissue  Soft - adipose (fatty) tissue   stores fat as food reserve which is source of energy insulates body and acts as padding Types of Tissue, Connective  Hard  Cartilage – tough, elastic material found between bones of spine and at end of long bones. Acts as shock absorber. Also found in nose, ears, and larynx  Bone – Forms rigid structure of human body. Has calcium salts, nerves, and blood vessels. Cartilage Bone Types of Tissue, Connective  Liquid  Blood – carries nutrients and oxygen to cells and carries metabolic waste away from cells.  Lymph – transports tissue fluid, proteins, fats and other material from tissues to circulatory system. Types of Tissue  Nerve – made up of neurons which transmit messages throughout body; composes nerves, brain, and spinal cord Types of Tissue, Muscle  Muscle – produces power and movement by contraction of muscle fibers  Types of Muscle Tissue  Skeletal – attaches to bones and provides for movement of body  Cardiac – causes heart to beat  Visceral (smooth) – present in walls of organs such as stomach, intestine, and blood vessels Skeletal Muscle Cardiac Muscle Smooth/Visceral Muscle Organs and Systems  Organ – two or more tissues joined together to perform specific function  System – organs and other body parts joined together to perform a particular function Summary Cells combine to form tissues. Tissues combine to form organs. Organs and other body parts combine to form systems.