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The Nervous System Functions of the Nervous System  Respond to internal and external stimuli  Transmit nerve impulses to and away from CNS  Interpret nerve impulses at the cerebral cortex  Assimilate experiences in memory and learning  Initiate glandular secretions and muscle contraction  Program instinctual behavior Organs and Divisions of the Nervous System  Central nervous system (CNS)— brain and spinal cord  Peripheral nervous system (PNS)—all nerves  Autonomic nervous system (ANS) – sympathetic and parasympathetic Cells of the Nervous System  Neurons  Consist of three parts  Cell body of neuron—main part  Dendrites—branching projections that conduct impulses to cell body of neuron  Axon—elongated projection that conducts impulses away from cell body of neuron Cells of the Nervous System  Neurons  Neurons classified according to function or direction of impulse  Sensory neurons: conduct impulses to the spinal cord and brain; also called afferent neurons  Motor neurons: conduct impulses away from brain and spinal cord to muscles and glands; also called efferent neurons  Interneurons: conduct impulses from sensory neurons to motor neurons; also called central or connecting neurons Nerves  Nerve—bundle of peripheral axons  Tract—bundle of central axons  White matter—brain or cord tissue composed primarily of myelinated axons (tracts)  Gray matter—brain or cord tissue composed primarily of cell bodies and unmyelinated fibers Nerves  Nerve coverings—fibrous connective tissue  Endoneurium—surrounds individual fibers within a nerve  Perineurium—surrounds a group (fascicle) of nerve fibers  Epineurium—surrounds the entire nerve Reflex Arcs  Nerve impulses are conducted from receptors to effectors over neuron pathways or reflex arcs  Conduction by a reflex arc results in a reflex (i.e., contraction by a muscle or secretion by a gland)  The simplest reflex arcs are two-neuron arcs— consisting of sensory neurons synapsing in the spinal cord with motor neurons; three-neuron arcs consist of sensory neurons synapsing in the spinal cord with interneurons that synapse with motor neurons Reflex Arcs Nerve Impulses  Self-propagating wave of electrical disturbance that travels along the surface of a neuron membrane; sometimes called action potentials Nerve Impulses  Mechanism  At rest, the neuron’s membrane is slightly positive on the outside—polarized—from a slight excess of Na+ on the outside  A stimulus triggers the opening of Na+ channels in the plasma membrane of the neuron  Inward movement of Na+ depolarizes the membrane by making the inside more positive than the outside at the stimulated point; this depolarization is a nerve impulse (action potential)  The stimulated section of membrane immediately repolarizes, but by that time the depolarization has already triggered the next section of membrane to depolarize, thus propagating a wave of electrical disturbances (depolarizations) all the way down the membrane The Synapse  Place where impulses are transmitted from one neuron to another (the postsynaptic neuron)  Synapse made of three structures—synaptic knob, synaptic cleft, and plasma membrane  Neurotransmitters bind to specific receptor molecules in the membrane of a postsynaptic neuron, opening ion channels and thereby stimulating impulse conduction by the membrane  https://youtu.be/Iws8w6NpsGg - easier video  https://youtu.be/L41TYxYUqqs- Bozman science Neurotransmitters Actions Disorder Involving It Acetylcholine -Triggers muscle contraction and stimulates the excretion of certain hormones -In CNS: involved in wakefulness, attentiveness, anger, aggression, etc. Alzheimer’s disease (lack of acetylcholine in certain areas of the brain) Dopamine -Controls movement and posture, modulates mood, and plays a central role in positive reinforcement and dependency Parkinson’s disease (loss GABA (gammaaminobutyric acid) -Contributes to motor control, vision, and many other cortical functions; regulates anxiety Drugs that increase GABA in the brain are used to treat epilepsy and Huntington’s disease Glutamate -Learning and memory Thought to be associated with Alzheimer’s disease, whose first symptoms include memory malfunctions Norepinephrine -Attentiveness, emotions, sleeping, dreaming, and learning; also released as a hormone into the blood, where it causes blood vessels to contract and heart rate to increase Mood disorders like manic depression Serotonin -Regulating body temperature, sleep, mood, appetite, and pain Depression, impulsive behavior, and aggressiveness of dopamine in certain areas of the brain) Central Nervous System (CNS)  Brain  Divisions  Brainstem  Cerebellum  Cerebrum  Spinal Cord Brain - Brainstem  Consists of three parts, named in ascending order: medulla oblongata, pons, and midbrain  Structure—white matter with bits of gray matter scattered through it  Functions  All three parts of brainstem are two-way conduction paths  Sensory tracts in the brainstem conduct impulses to the higher parts of the brain  Motor tracts conduct from the higher parts of the brain to the spinal cord  Many important reflex centers lie in the brainstem Brain - Brainstem  Medulla oblongata  Connects brain to spinal cord  Regulates breathing, heart and blood vessel function, digestion, sneezing, and swallowing  Pons  Helps relay messages from the cortex and the cerebellum  Midbrain  Associated with vision, hearing, motor control, sleep/wake, arousal (alertness), and temperature regulation Brain - Cerebellum  Second largest part of the human brain  Helps control muscle contractions to produce coordinated movements so that we can maintain balance, move smoothly, and sustain normal postures  Recent evidence shows the coordinating effects of the cerebellum may be more extensive, also assisting the cerebrum and other regions of the brain Brain - Cerebrum  Largest part of the human brain  Outer layer of gray matter is the cerebral cortex; made up of lobes; composed mainly of dendrites and cell bodies of neurons  Interior of the cerebrum composed mainly of white matter (i.e., nerve fibers arranged in bundles called tracts)  Functions of the cerebrum—mental processes of all types, including sensations, consciousness, memory, and voluntary control of movements Brain – Lobes of the Cerebrum  Frontal Lobe  Personality, behavior, emotions  Judgment, planning, problem solving  Speech: speaking and writing (Broca’s area)  Body movement (motor strip)  Intelligence, concentration, self awareness  Occipital Lobe  Interprets vision (color, light, movement)  Parietal Lobe  Interprets language, words  Sense of touch, pain, temperature (sensory strip)  Interprets signals from vision, hearing, motor, sensory and memory  Spatial and visual perception  Temporal Lobe  Understanding language (Wernicke’s area)  Memory  Hearing  Sequencing and organization Deep Structures of the Brain  Hypothalamus gland: hunger, thirst, sleep, and sexual response, regulates body temperature, blood pressure, emotions, and secretion of hormones  Pituitary gland: known as the “master gland,” it controls other endocrine glands in the body; produces many hormones  Pineal gland: regulates the body’s internal clock and circadian rhythms by secreting melatonin  Thalamus: serves as a relay station for almost all information that comes and goes to the cortex  Limbic system (includes hypothalamus, amygdala, and hippocampus)  Amygdala: emotional reactions  Hippocampus: memory  Corpus callosum: allows for communication between hemispheres Brain Myths: Fact or Fiction? 1. You only use 10% of your brain. 2. A person can be either left-brained or right-brained. 3. Each person’s brain has a set learning style. 4. Some people are able to multitask very well. Testing your memory  I will recite a list of 10 words  Do not record them in any way  Try to remember as many of them as you can (in order if possible)  You will then be able to write them down to see what you were able to remember  Sunflower ball  Red money  Chair rain  Woman  Globe  Comb  theater Spinal Cord  Columns of white matter, composed of bundles of myelinated nerve fibers, form the outer portion of the H-shaped core of the spinal cord; bundles of axons called tracts  Interior composed of gray matter made up mainly of neuron dendrites and cell bodies  Spinal cord tracts provide two-way conduction paths— ascending and descending  Spinal cord functions as the primary center for all spinal cord reflexes; sensory tracts conduct impulses to the brain, and motor tracts conduct impulses from the brain Coverings and fluid spaces of the brain and spinal cord  Coverings  Cranial bones (skull) and vertebrae  Cerebral and spinal meninges  Fluid spaces  Subarachnoid spaces of meninges  Central canal inside cord  Ventricles in brain  Fluid  Cerebrospinal fluid – cushions and provides immune protection Peripheral Nervous System (PNS)  Cranial nerves  12 pairs—attached to undersurface of the brain  Connect brain with the neck and structures in the thorax and abdomen  Spinal nerves  31 pairs—contain dendrites of sensory neurons and axons of motor neurons  Conduct impulses necessary for sensations and voluntary movements  After exiting the vertebral column, they split, combine, and split again forming a plexus (there are 4)     Cervical plexus Brachial plexus Lumbar plexus Sacral plexus Autonomic Nervous System  Responsible for controlling unconscious bodily functions (heartbeat, breathing, digestion)  Composed of two divisions: the sympathetic system and the parasympathetic system Autonomic Nervous System  Sympathetic nervous system  Serves as the emergency or stress system, controlling visceral effectors during strenuous exercise and when strong emotions (anger, fear, hate, or anxiety) are elicited  Group of changes induced by sympathetic control is called the fight-or-flight response  Parasympathetic nervous system  Dominates control of many visceral effectors under normal, everyday conditions