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Mental Health Nursing II NURS 2310 Unit 15 Cognitive Impairment and Thought Disorders Key Terms Psychosis = Disorganization of the personality, deterioration in social functioning, and loss of contact with or distortion of reality; may include hallucinations and/or delusions Hallucinations = False sensory perceptions not associated with real external stimuli affecting any or all of the five senses Illusions = Misinterpretations/misperceptions of real external stimuli Delusions = False personal beliefs not consistent with intelligence or culture; belief continues to exist in spite of proof to the contrary Paranoia = Extreme suspiciousness of others and of their actions/perceived intentions Depersonalization = Feelings of unreality Anhedonia = Inability to experience pleasure Religiosity = Excessive demonstration of or obsession with religious ideas/behavior Magical thinking = Belief that one’s thoughts or behaviors can control certain situations/people Neologisms = Invented words that have symbolic meaning to self but are meaningless to others Echolalia = Repetition of words one hears in attempt to identify with the speaker Echopraxia = Imitation of movements made by others in an attempt to identify with them Perseveration = Persistent repetition of the same word/idea in response to different questions or other prompts Looseness of associations = Shifting of ideas from one unrelated subject to another Word salad = Random arrangement of groups of words that lacks any logical connection Circumstantiality = Delay in reaching the point of communication due to unnecessary/tedious details; inability to track the discussion topic Tangentiality = Inability to get to the point of communication; unrelated topics are introduced and original discussion is lost Clang associations = Word choice is determined by sound instead of meaning (i.e. rhyming) Mutism = Refusal or inability to speak Catatonia = A state of stupor (extreme psychomotor retardation) or excitement (extreme psychomotor agitation) that is usually associated with a psychotic disorder Waxy flexibility = Passive yielding of ones’ body to positioning/posturing by others Cognitive Impairment Delirium Cognitive disturbance manifested by disorientation, agitation, memory impairment, and inability to reason or partake in goal-directed activity  Develops within several hours or days; onset may be more abrupt (i.e. following head injury or seizure)  May be caused by systemic illness, metabolic imbalance, ingestion of toxins, drug or alcohol overdose, withdrawal from drugs/alcohol or medication  Symptoms of Delirium Rambling, incoherent speech  Extreme distractibility  Hallucinations and/or illusions  Sleep disturbances with vivid nightmares  Hyperactivity/hypervigilance or catatonic stupor  Emotional instability (irritability, murmuring, moaning, fleeing or lashing out)  Autonomic manifestations (tachycardia, sweating, dilated pupils)  Progression of Delirium Brief in duration (1 week to 1 month)  Symptoms diminish within 3 days to 1 week of resolution of underlying cause (full recovery may take up to 2 weeks)  May transition into a permanent cognitive disorder (i.e. dementia) if left unresolved  CBC, BMP, chemistry panel used to diagnose underlying cause  Treated by determination/correction of underlying cause (i.e. fluid/electrolyte status corrections, treatment of hypoxia, anoxia, or diabetic problems)  Neurocognitive Disorder (NCD) Previously termed dementia  Progressive decline in cognitive function due to damage or disease in the brain beyond what might be expected from normal aging  Develops slowly over several months or years  Progression is typically irreversible  Diagnosed by evaluation (i.e. mental status exam/MSE, CT scan, ruling out of other underlying causes of symptomology)  Treatment focused on symptom management  Categorized as primary or secondary NCD  Primary NCD The neurocognitive disorder itself is the major sign of an organic brain disease that is not directly related to another organic illness  Alzheimer’s disease is the most common cause of primary NCD; vascular insufficiency (as in stroke) is another common cause  Secondary NCD Occurs as a result of a physical disease or injury (directly related to another condition)  Causes include HIV, cerebral trauma; substance abuse  Symptoms of NCD Impairment in abstract thinking/judgment; lack of impulse control  Uninhibited/inappropriate behavior; disregard of social conduct; personality changes  Neglectful of personal appearance/hygiene  Apraxia (inability to carry out motor activities)  Aphasia (inability to express needs)  Irritability, mood instability, sudden outbursts  Unable to comprehend own limitations; at risk for accidents or wandering away from home  Stages of NCD related to Alzheimer’s Stage 1 = no apparent symptoms  Stage 2 = forgetfulness  Stage 3 = mild cognitive decline (interference with work performance)  Stage 4 = mild-to-moderate cognitive decline; confusion (confabulation common)  Stage 5 = moderate cognitive decline; early NCD (begins to lose independence)  Stage 6 = moderate-to-severe cognitive decline; middle NCD (disorientation)  Stage 7 = severe cognitive decline; late NCD (bedfast, aphasic, and immobile)  Medications for Clients with NCD  Cholinesterase inhibitors – Treats cognitive impairment – Side effects: dizziness, headache, GI upset – Examples: tacrine (Cognex), donepezil (Aricept), and rivastigmine (Exelon)  Antipsychotic agents – Treats agitation, aggression, hallucinations, thought disturbances, and wandering – Side effects: headache, dizziness, drowsiness – Examples: risperidone (Risperdal), olanzapine (Zyprexa), quetiapine (Seroquel), and haloperidol (Haldol)  Antidepressants – Treats depression, depression-related insomnia – Side effects: headache, drowsiness/dizziness – trazodone (Desyrel), mirtazapine (Remeron)  Anxiolytics – Treats anxiety – Side effects: drowsiness/dizziness, GI upset – lorazepam (Ativan)  Sedative-hypnotics – Treats insomnia – Side effects: headache, drowsiness/dizziness – zolpidem (Ambien), eszopiclone (Lunesta) Nursing Care for Clients with Cognitive Impairment  Promote client safety – remain with client at all times to monitor behavior and provide reorientation and assurance – maintain room in low level of stimuli  Frequently orient client to reality – use clocks and calendars with large numbers – allow client to have personal belongings Preserve the dignity of the client  Help client’s family/primary caregivers to facilitate care  Assist in dealing with caregiver burnout   Keep explanations simple – use face-to-face interaction – speak slowly and do not shout  Discourage rumination of delusional thinking – talk about real events and real people Monitor for medication side effects  Allow plenty of time for client to perform tasks  Follow usual routine as closely as possible with regard to ADLs  Provide guidance and support for independent actions by talking the client through the task one step at a time  Thought Disorders Brief Psychotic Disorder Sudden onset of psychotic symptoms that last at least 1 day but less than 1 month  May or may not be preceded by a severe psychosocial stressor  Full recovery to premorbid level of function  Schizophreniform Disorder Identical to schizophrenia with the exception of duration (symptoms last at least 1 month but less than 6 months)  Prognosis is good, with full recovery to premorbid level of function likely  Schizoaffective Disorder  Diagnosis of both schizophrenia and a mood disorder, such as MDD Delusional Disorder Presence of one or more nonbizarre delusions that persist for at least 1 month  Hallucinations are not present or are not prominent  Behavior is not bizarre  Delusions may be erotomanic, grandiose, jealous, persecutory, or somatic in nature  Types of Delusional Disorder  Erotomanic = Belief that someone (usually famous) is in love with oneself  Grandiose = Irrational ideas regarding one’s own worth, talent, knowledge, or power  Jealous = Belief that one’s sexual partner is unfaithful in the absence of substantiation  Persecutory = Belief that one is being treated malevolently in some way  Somatic = Belief that one suffers from a physical defect, disorder, or disease (such as an internal parasite or infestation of insects in/on the skin) Schizophrenia Disturbance in thought processes, perception, and affect that results in severe deterioration of social/occupational functioning  Symptoms categorized as positive or negative  – Positive symptoms = in excess of normal function  Hallucinations, delusions, disorganized behavior, disorganized thinking and speech  Good response to antipsychotic medications – Negative symptoms = deficit in normal function  Affective flattening, alogia (poverty of speech), avolition (inability to initiate goal-directed activity), apathy, anhedonia, social isolation  Poor response to treatment/medication Phases of Schizophrenia  Phase I: Premorbid Phase – indifferent to social relationships – appear cold and aloof – does not always progress to schizophrenia  Phase II: Prodromal Phase – social withdrawal – peculiar or eccentric behavior – bizarre ideas – unusual perceptual experiences – neglectful of personal hygiene and grooming – lack of initiate, interests, or energy – phase may last for many years  Phase III: Schizophrenia – delusions and/or hallucinations – disorganized speech – disorganized or catatonic behavior – affective flattening – marked decrease in level of functioning – persists for at least 6 months  Phase IV: Residual Phase – usually follows active phase of the disease – flat affect and impairment in role functioning – residual impairment usually increases after each exacerbation with active disorder Medication Management of Schizophrenia  Typical antipsychotic agents – Side effects: nausea, sedation, EPS – Examples: chlorpromazine (Thorazine), fluphenazine (Prolixin), and haloperidol (Haldol)  Atypical antipsychotic agents – Side effects: drowsiness, dizziness, constipation, dry mouth, headache, nausea/vomiting, EPS – Examples: quetiapine (Seroquel), olanzapine (Zyprexa), clozapine (Clozaril), ziprasidone (Geodon), aripiprazole (Abilify), risperidone (Risperdal), and paliperidone (Invega) Communicating with Clients with Thought Disorder Use nonconfrontational speech and mannerisms  Encourage communication and expression of feelings and fears  Decrease stimuli and offer quiet activity  Seek clarification of statements  Provide recognition for constructive self-care activities  Make adjustments in food preparation and service for patients with paranoia  Establish therapeutic rapport by listening, sharing observations, and accepting silence  Patient Education for Clients with Cognitive Impairment or Thought Disorder Nature of the illness (causes, symptoms)  Management of the illness  – ways to ensure client safety – how to maintain reality orientation – providing assistance with ADLs – nutritional information – difficult behaviors – medication administration – matters related to hygiene and toileting  Support services – financial/legal assistance – support groups and respite care Nursing Process for Clients with Cognitive Impairment or Thought Disorder  Assessment – information gathered from a number of sources because client is likely to be a poor historian  Diagnosis – disturbed thought processes R/T delusions (or concrete thinking or paranoia) AEB bizarre statements and behaviors – disturbed sensory perception R/T hallucinations (or illusions) AEB inability to tolerate group therapy, talking to self, or looking for or at something that is not there – self-care deficit R/T withdrawal and loss of motivation and judgment AEB poor hygiene, poor grooming, and avoiding others  Planning – development of the nursing care plan  Intervention – rapport building – limit-setting – communicating expectations – client/family education  Evaluation – focus is on short-term goals as opposed to longterm goals – resolution of identified problems is unrealistic – outcomes must be measured in terms of slowing down the process rather than stopping or curing the problem