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Chapter 41 Introduction to Anatomy and Physiology Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Introduction to Anatomy and Physiology • Anatomy  The study, classification, and description of structures and organs of the body • Physiology  Explains the processes and functions of the various structures and how they interrelate with one another Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 2 Anatomical Terminology • Terms that specifically locate a structure  Anterior—to face forward  Cranial—toward the head  Caudal—toward the tail  Superior—toward the head or above  Inferior—lower, below another  Medial—toward the midline  Lateral—toward the side  Proximal—nearest the trunk  Distal—farthest from the trunk  Superficial—nearer the body surface  Deep—farther away from the body surface Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 3 Anatomical Terminology • Body planes  Sagittal • Divides the body into right and left halves  Coronal • Divides the body into front and back halves  Transverse • Divides the body into caudal and cranial portions Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 4 Figure 41-2 (From Thibodeau, G.A., Patton, K.T. [2008]. Structure and function of the body. [13th ed.]. St. Louis: Mosby.) Directions and planes of the body. Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 5 Anatomical Terminology • Body cavities  Ventral cavity • Thoracic cavity • Heart and lungs • Abdominopelvic cavity • Abdominal o • Stomach, kidneys, liver, gallbladder, spleen, pancreas, and a large portion of the intestines Pelvic o Lower portion of the intestines, urinary bladder, and internal structures of the reproductive system Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 6 Anatomical Terminology • Body cavities (continued)  Dorsal cavity • Cranial cavity • Brain • Spinal cavity • Spinal cord Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 7 Figure 41-3 (From Thibodeau, G.A., Patton, K.T. [2008]. Structure and function of the body. [13th ed.]. St. Louis: Mosby.) Location and subdivisions of the dorsal and ventral body cavities as viewed from the front (anterior) and from the side (lateral). Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 8 Abdominal Regions • Nine abdominal regions  Right hypochondriac region: liver, gallbladder  Epigastric region: liver, stomach  Left hypochondriac region: stomach, large intestine  Right lumbar region: large, small intestine  Umbilical region: transverse colon, small intestine  Left lumbar region: small intestine, colon  Right iliac (inguinal) region: cecum, small intestine  Hypogastric region: small intestine, bladder, appendix  Left iliac (inguinal) region: colon, small intestine Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 9 Figure 41-4 (From Thibodeau, G.A., Patton, K.T. [2008]. Structure and function of the body. [13th ed.]. St. Louis: Mosby.) The nine regions of the abdominopelvic cavity. Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 10 Abdominopelvic Quadrants • Physicians and other health professionals frequently divide the abdomen into four quadrants to describe the site of pain or locate internal pathology  Right upper quadrant: liver, gallbladder  Left upper quadrant: spleen  Right lower quadrant: appendix  Left lower quadrant: colon Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 11 Figure 41-5 (From Thibodeau, G.A., Patton, K.T. [2008]. Structure and function of the body. [13th ed.]. St. Louis: Mosby.) The abdomen divided into right and left upper quadrants and right and left lower quadrants. Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 12 Structural Levels of Organization • Organization is one of the most important characteristics of body structure.  Chemical level • Atoms: smallest unit of matter • Molecules: two or more united atoms  Cellular level: smallest living unit  Tissue level: organized group of cells  Organs: group of tissues  System level: organized group of organs  Organism (human being) Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 13 Structural Levels of Organization • Cell  Structural parts • Plasma membrane • • Keeps cell whole and intact Selectively permeable • Cytoplasm • • Sticky, fluid-like substance (nutrients) between the plasma membrane and the nucleus Contains organelles o Tiny functioning structures o Nucleus, endoplasmic reticulum, ribosomes, mitochondria, lysosomes, Golgi apparatus, centrioles Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 14 Figure 41-7 (From Herlihy, B., Maebius, N.K. [2007]. The human body in health and illness. [3rd ed.]. Philadelphia: Saunders.) A typical cell. Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 15 Structural Levels of Organization • Nucleus  Largest organelle  Responsible for cell reproduction and control of other organelles  Surrounded by nuclear membrane  Contains nucleoplasm: refined cytoplasm  Two structures: • Nucleolus  Critical in formation of protein • Chromatin granules  Composed of protein and DNA Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 16 Structural Levels of Organization • Endoplasmic reticulum  Smooth and rough; Functions as a miniature circulation system • Ribosomes  Produce enzymes and proteins • Mitochondria  Convert food to energy ATP • Lysosomes  Contain enzymes that digest food and microbes • Golgi apparatus  Packaging plant • Packages certain carbohydrate and protein compounds into globules, then releases them outside of the cell • Centrioles   Aid in the formation of the spindle during mitosis • Necessary for cell reproduction Mosby items and derived items © 2011, organelles 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Paired, rodshaped Slide 17 Structural Levels of Organization • Protein synthesis  DNA (deoxyribonucleic acid) • Located in the nucleus • Chemical blueprint •  Encodes the message for protein synthesis and sends it to RNA RNA (ribonucleic acid) • Located in the cytoplasm • Chemical messenger • Transports DNA message to ribosomes where the protein is produced Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 18 Structural Levels of Organization • Cell division  Mitosis • Reproduction of cells • One cell divides to form two daughter cells • Chromosomes • • • • • Located in the nucleus Carry genes responsible for the organism’s traits Each body cell contains 46 chromosomes Each exists in pairs (one from the father and one from the mother) Four phases of mitosis • Prophase, metaphase, anaphase, telophase Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 19 Structural Levels of Organization • Mitosis  Prophase: chromosomes form two strands (chromatids); centrioles form spindle fibers  Metaphase: spindle fibers attach to chromatids  Anaphase: cell division begins  Telophase: two nuclei appear; two new cells developed Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 20 Structural Levels of Organization • Movement of materials across cell membranes  Active transport • Movement of material across the membrane of a cell by means of a chemical activity that allows the cell to admit larger molecules than would otherwise be able to enter • Requires energy Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 21 Structural Levels of Organization • Types of active transport  Phagocytosis—Movement of cells or other large particles into the cell by trapping them in a section of plasma membrane   Pinocytosis—Movement of fluid and dissolved molecules into a cell by trapping them in a section of plasma membrane   White blood cells trapping bacteria Cell trapping protein molecule Pump (calcium or sodium-potassium)—Movement of solute particles from an area of low concentration to an area of higher concentration by means of a carrier molecule  Muscle cell action Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 22 Structural Levels of Organization • Passive transport    Movement of small molecules across the membrane of a cell by diffusion No energy is required Types • Diffusion—Solid particles in a fluid move from an area of higher concentration to an area of lower concentration o Nerve cell impulse • Osmosis—The passage of water across a selectively permeable membrane, with water molecules going from the less concentrated solution to the more concentrated solution o Water imbalance correction • Filtration—The movement of water and particles through a membrane by force o Small solutes moving from high pressure to low pressure Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 23 Structural Levels of Organization • Tissues  Epithelial tissue • Covers outside of the body and some internal structures • Functions • • • Protection Absorption Secretion Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 24 Structural Levels of Organization • Types of epithelial tissue  Simple squamous • Alveoli of lungs and lining of vessels  Simple columnar • Lining of stomach, intestines, and respiratory tract  Stratified squamous • Lining of mouth and esophagus; surface of skin  Stratified transitional • Urinary bladder Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 25 Structural Levels of Organization • Connective tissue  Connects • Joins tissues or structures to the body  Types • • • • • • • Areolar: between tissues and organs Adipose: under skin Dense fibrous: tendons Bone: skeleton Cartilage: ear Blood: vessels Hematopoietic: bone marrow Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 26 Structural Levels of Organization • Muscle tissue   Contracts in response to a message from the brain or spinal cord Types • Skeletal • Voluntary; attached to bones • Cardiac • Involuntary; form the heart • Smooth (visceral) • • Involuntary Lining of internal organs (blood vessels, stomach, intestines, uterus) Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 27 Structural Levels of Organization • Nervous tissue  Provides rapid communication between body structures and control of body functions  Brain, spinal cord, nerves  Neurons • Transmit impulses or messages  Glial cells • Support and nourish the neurons Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 28 Structural Levels of Organization • Membranes  Epithelial membranes • Mucous membranes •  Line body surfaces that open to the outside • Nose, mouth, urinary tract, reproductive tract, etc. Secrete mucus • Thick, slippery material • Keeps membranes soft and moist • Protects against bacterial invasion • Lubricant in GI tract Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 29 Structural Levels of Organization • Serous membranes  Line body surfaces that do not open to the outside • Lungs, intestines, heart  Secrete serous fluid • Thin, watery fluid  Two layers • Parietal membrane (lines the wall of the cavity) • Visceral membrane (covers the surface of the organ) Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 30 Structural Levels of Organization • Connective tissue membranes (synovial membranes)   Line the joint spaces between bones and prevent friction Secrete synovial fluid • Thick, colorless lubricating fluid Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 31 Structural Levels of Organization • Organs/systems  Integumentary • • • • • • Skin Hair Nails Sense receptors Sweat glands Oil glands Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 32 Structural Levels of Organization • Skeletal system   Bones Joints • Muscular system  Muscles • Nervous system    Brain Spinal cord Nerves • Circulatory system  Heart and blood vessels Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 33 Structural Levels of Organization • Endocrine system  Pituitary glands  Pineal gland  Hypothalamus  Thyroid gland  Parathyroids  Thymus  Adrenals  Pancreas  Ovaries (female)  Testes (male) Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 34 Structural Levels of Organization • Lymphatic system     Lymph nodes and vessels Thymus Spleen Tonsils • Respiratory system  Nose  Pharynx  Larynx  Trachea  Bronchi  Lungs Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 35 Structural Levels of Organization • Digestive system (primary organs)  Mouth  Pharynx  Esophagus  Stomach  Small intestine  Large intestine  Rectum  Anal canal Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 36 Structural Levels of Organization • Digestive system (accessory organs)  Teeth  Salivary glands  Tongue  Liver  Gallbladder  Pancreas  Appendix Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 37 Structural Levels of Organization • Urinary system  Kidneys  Ureters  Urinary bladder  Urethra Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 38 Structural Levels of Organization • Reproductive system (male)  Gonads • Testes  Genital ducts • Vas deferens • Urethra  Accessory glands • Prostate   Supporting structures Genitalia • Penis and scrotum Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 39 Structural Levels of Organization • Reproductive system (female)  Gonads • Ovaries  Accessory organs • Uterus • Fallopian tubes • Vagina  Supporting structures  Genitalia • Vulva  Mammary glands (breasts) Mosby items and derived items © 2011, 2006, 2003, 1999, 1995, 1991 by Mosby, Inc., an affiliate of Elsevier Inc. Slide 40