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Injection Administration Techniques Rachel Nowak, PharmD Clinical Instructor, UWSOP Bartell Drugs Clinical Coordinator January 29, 2010 Objectives Describe proper techniques for administering injectable drugs  Describe precautions to take when administering injectable products  Appreciate pharmacist role in administering injectable medications  Vaccines 101 Immunity  Passive Immunity – Antibody produced by one human or other animal is transferred to another – Temporary protection • Example: Immunity an infant receives from its mother  Active Immunity – Immune system is stimulated to produce cellular and humoral immunity – Lasting protection • Example: Survive infection from the disease causing organism Basic MOA of Vaccines Vaccinations produce active immunity.  Immune response and immunologic memory produced is similar to that caused by natural infection.  Comes without the risks of the actual disease and associated complications.  Classifications of Vaccines  Live attenuated – Attenuated or weakened form of diseasecausing bacterium or virus – Must replicate to be effective • Uncontrolled replication of the vaccine virus can cause severe reactions - only occurs in patients with immunodeficiency – Immune response is cellular & humoral – Circulating antibodies interfere – Usually produce immunity after one dose Classifications of Vaccines  Inactivated – Inactivated form of bacterium or virus – Can’t replicate • Can’t cause disease, even in immunodeficient patients – Immune response primarily humoral – Less affected by circulating antibody than live vaccines – Always requires more than one dose – Antibody titer decline over time Immunization Procedures Screening  Standard Questions – Do you have any drug/food allergies? – Do you have any chronic diseases? – What medications do you take? Basic Vaccine Screening Questions    Are you sick today? Are you allergic to latex? Do you have any allergies to any vaccine or vaccine components? – Ex: Eggs, gelatin    Have you ever had a serious reaction after receiving a vaccine? Have you had Guillian-Barre Syndrome in the past? Is it possible that you could be pregnant? Breastfeeding? Additional Vaccine Screening Questions     Do you have cancer, leukemia, AIDs, or any other immune system problem? Do you take cortisone, prednisone, other steroids, anticancer drugs, or have you had radiation treatments? In the past year, have you received a transfusion of blood or blood products or been given immune globulin or an antiviral medication? Have you received any vaccinations in the past 4 weeks? Consent Answer any questions patient may have  Patient needs to understand benefits and risks of getting immunized and consent to vaccine administration.  – If it is a child under 18, then parent or guardian consent should be obtained Vaccine Information Statements (VIS)  Patient education sheets developed by the CDC – Helps to explain the risks and benefits of receiving a particular vaccine  Federal law requires that VISs be used for most vaccines when vaccinating patients – Should be given before vaccine administered Parts of a Syringe Preparing Syringe  Choose correct SYRINGE size – If <0.5ml need low-dose syringe (1mL, 3mL) – Finely graduated syringe will ensure accurate amount – Fluzone (influenza) is 0.5mL dose – Pneumovax (pneumonia) is 0.5mL dose  Maximum volumes – Deltoid – No more than 0.5-1mL – Large muscle (gluteus medius) • Adult – no more than 4mL • Child – no more than 1-2mL Needle Lengths and Gauges Preparing Needle Choose correct needle LENGTH and GAUGE  Minimize tissue injury and SQ leakage  Allow easy passage (23 vs. 25 gauge)  Needle length depends on injection site  – Adults 5/8” vs. 1” vs. 1.5” – Children 5/8” vs. 1” – If less SQ fat, use smaller needle Get Organized  Get all supplies ready in advance – ex: Band-Aid, alcohol pad, cotton ball, VIS  Double Check – Correct vaccine, dose, & expiration date – Go over screening/consent form with patient  Record – Vaccine name, manufacturer, lot number, expiration date – Location of administration (L/R deltoid) – Provider administering the vaccine – Vaccine Information Sheet publication date Administer the Vaccine  Cleanse area with alcohol swab – Allow alcohol to dry  Target – C technique and shoot (IM) – Bunch skin (SQ)  Inject – DO NOT Aspirate – Dart-like motion with steady pressure – Inject at: • 90° angle for IM • 45° angle for SQ Final Steps        Do not recap needle Dispose of needle properly Apply pressure to injection site with cotton ball (if necessary) Apply adhesive bandage Provide patient with immunization record & Vaccine Information Statement (VIS) Record all necessary information Have patient remain under surveillance for ~15 minutes Routes of Administration Intramuscular (IM) Injections Subcutaneous (SQ) Injections Self-Injection Teaching: Insulin Advise patients to wash hands  Have patient confirm type of insulin on bottle label  Roll vial or pen in palms, if appropriate  Show patients in counseling where to read dose on syringe and appropriate amount to draw  – Ensure using best syringe for dose   Inject at 90° angle for SQ insulin Injecting into the subcutaneous fat of the belly most common – Site should be approximately 2 inches from belly button  Rotate sites – avoid formation of fatty deposits or scarring Insulin Injection Sites  Alternate sites include the back of the arms, thighs, and buttocks – Slower onset with alternate sites Self-Injection Teaching: Insulin  Go over insulin storage – Generally insulin not in use should not be stored in fridge – Extreme temperatures and excess agitation should be avoided  Discard dates – Important to go over how long insulin can be stored at room temperature Insulin inspection  Mixing of Insulins  Proper disposal of sharps  Self-Injection Teaching  Pen devices/ insulin cartridges: – Deliver insulin subcutaneously through a needle. – All a little different and might require extra teaching time – In specific patient populations these devices have been demonstrated to improve: • accuracy of administration • adherence – Requires needle to be left embedded in skin for at least 5 seconds after plunger depressed Managing Adverse Reactions Vasovagal Syncope (Fainting) Be aware of patient behavior  Have patient sit before administration  Lay patient down if necessary  Check airway, breathing and vital signs  Anaphylaxis Rare but potentially fatal  Occurs within 15 minutes  Call 911  Lay patient down, check airway, breathing, vital signs  Be prepared and ready to administer epinephrine (Epipen)  Delayed Adverse Reactions Child – fever, fussy, crying, injection site  Adult – injection site discomfort  Symptomatic relief  – Fluids – Pain medications • No aspirin for children • Acetaminophen (Tylenol) • Ibuprofen (Advil, Motrin) Reporting Adverse Reactions   Vaccine Adverse Event Reporting System (VAERS) Required for: - Rare, serious or unexpected events Emergency Plan and Training Access to Emergency Medical Services (EMS) – phone on hand  Be prepared for adverse reactions  – CPR trained staff – Necessary medications on hand – Have patient remain under surveillance after administration Universal Precautions Controlling Infection Transmission Be Prepared  Control infection transmission – Use universal precautions – Proper cleaning and disposal of waste  Anticipate adverse effects  Assure patient safety – Know your equipment – Establish quality procedures – Practice good technique Protect Yourself: Use Universal Precautions  Infection control guidelines designed to protect workers from exposure to diseases spread by blood and certain body fluids  Assume all patients to be infectious for blood-borne diseases Universal Precautions Apply To: Blood  semen  vaginal secretions  synovial fluid       cerebrospinal fluid pleural fluid peritoneal fluid pericardial fluid amniotic fluid Universal precautions should be applied to all body fluids when it is difficult to identify the specific body fluid or when body fluids are visibly contaminated with blood. Universal Precautions DO NOT necessarily apply to:     feces nasal secretions sputum sweat     tears urine vomit saliva (except in the dental setting) But, you must still be mindful of transmitting infectious material. They may not carry blood-borne illness, but they do carry viruses and bacteria. Universal Precautions  Wear gloves if likely to touch body substances or mucous membranes – Latex or non-latex – Monitor for allergies Wear eye protection if likely to be splashed  Wear lab coat or gown if likely to be soiled  Universal Precautions Place needles in special containers (Sharps Container)  Place soiled articles in plastic bag for disposal  Place soiled linen in laundry bag  Pharmacists Role Pharmacist Role Dispensing versus administration  Makes sense for:  – Vaccinations – Teaching patients to self-inject • Insulin and glucagon • Increasing availability of self-injection products – Allergic reactions, migraine, MS, infertility  Proper training required Why are immunizations so important?  Profession: – Establishes the role of the pharmacist  Patients: – Pharmacists are easily accessible  Population: – Preventing disease For More Information APhA: Pharmacy-Based Immunization Delivery Certificate Program – www.pharmacist.com  Center for Disease Control – Vaccines – http://www.cdc.gov/vaccines  Vaccine Adverse Event Reporting System – http://vaers.hhs.gov 
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                             
                                            