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Spinal Cord - eCurriculum
Spinal Cord - eCurriculum

Somatosensory Systems: Pain and Temperature - Dr
Somatosensory Systems: Pain and Temperature - Dr

... The Basic Plan for Somatosensory Information to Consciousness The systems that transmit somatosensory information to the level of consciousness follow a basic plan. (see Figure 1) Adequate stimuli evoke generator potentials in peripheral receptors or end organs. Adequate Stimulus – The stimulus moda ...
Lesi Medula Spinalis Khronis
Lesi Medula Spinalis Khronis

embryonic development of the leech nervous system
embryonic development of the leech nervous system

lecture 12 - McLoon Lab - University of Minnesota
lecture 12 - McLoon Lab - University of Minnesota

... • They synapse in the ventral posterolateral nucleus (VPL) of the thalamus. • Axons from the VPL neurons project to somatosensory cortex. ...
String Art: Axon Tracts in the Spinal Cord Spinal reflex arcs
String Art: Axon Tracts in the Spinal Cord Spinal reflex arcs

Copyrighted Material
Copyrighted Material

Got diversity? Wiring the fly brain with Dscam
Got diversity? Wiring the fly brain with Dscam

Nerve
Nerve

... Contains receptors Transmits information from receptors to the CNS ...
Axonogenesis in the Brain of Zebrafish Embryos
Axonogenesis in the Brain of Zebrafish Embryos

Reconstruction of the nigrostriatal dopamine pathway in the adult
Reconstruction of the nigrostriatal dopamine pathway in the adult

... In rodent experiments intranigral DA neuron grafts have shown no or very limited growth of axons along the nigrostriatal pathway towards the striatum (Nikkhah et al., 1994a; Mendez et al., 1996; Bentlage et al., 1999; Mukhida et al., 2001). Previous studies have suggested that the growth territory b ...
REVIEWS - Department Of Biological Sciences Hunter College
REVIEWS - Department Of Biological Sciences Hunter College

... to diverse functions ranging from cell–cell adhesion to ...
Nervous System Part 6
Nervous System Part 6

Pax6 in the cerebellum - Development
Pax6 in the cerebellum - Development

On acute gene expression changes after ventral root replantation
On acute gene expression changes after ventral root replantation

M555 Medical Neuroscience Cervical Thoracic Lumbar Sacral
M555 Medical Neuroscience Cervical Thoracic Lumbar Sacral

... Lateral Horn of Spinal Cord Gray Matter more formally known as the Intermediolateral Column location: lateral margin of gray matter at spinal levels Thoracic 1 – Lumbar 3 the Lateral Horn and Clarke’s Nucleus are located at the same spinal levels, but they have nothing to do with one another signifi ...
Results: Mitochondrial transport in dendrites and axons Maximum
Results: Mitochondrial transport in dendrites and axons Maximum

Combinatorial Marking of Cells and Organelles with Split
Combinatorial Marking of Cells and Organelles with Split

A Functional Role for Intra-Axonal Protein Synthesis during Axonal
A Functional Role for Intra-Axonal Protein Synthesis during Axonal

Comparison of nerve cord development
Comparison of nerve cord development

Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord
Lbx1 marks a subset of interneurons in chick hindbrain and spinal cord

... References Auclair, F., Marchand, R., Glover, J.C., 1999. Regional patterning of reticulospinal and vestibulospinal neurons in the hindbrain of mouse and rat embryos. J. Comp. Neurol. 411, 288±300. Briscoe, J., Pierani, A., Jessell, T.M., Ericson, J., 2000. A homeodomain protein code speci®es progen ...
MAG, Nogo-A and NgR in Hippocampal Development and Regeneration TESIS DOCTORAL
MAG, Nogo-A and NgR in Hippocampal Development and Regeneration TESIS DOCTORAL

... Fig. 3.2. Orthogonal stereoviews of the NgR structure Fig. 3.3. MAI receptor complex formed by NgR, p75 and Lingo Fig. 3.4. Structure of Lingo-1 Fig. 3.6. A cultured sensory neuron extending a growth cone with long thin filopodia Fig. 3.7. The actin and microtubule cytoskeleton in the growth cone Fi ...
UNC-119 suppresses axon branching
UNC-119 suppresses axon branching

Module 5 – Spinal Cord and Peripheral Nerves The Spinal Cord
Module 5 – Spinal Cord and Peripheral Nerves The Spinal Cord

... Ventral root - contains the axons of motor neurons (issues motor commands to effector glands and muscles) Dorsal root - contains the axons of sensory neurons (relays sensory input from receptors to the spinal cord) o Cell bodies of sensory neurons lie within the dorsal root ganglion While th ...
LECTURE OF NERVOUS SYSTEM
LECTURE OF NERVOUS SYSTEM

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Netrin



Netrins are a class of proteins involved in axon guidance. They are named after the Sanskrit word ""netr"", which means ""one who guides."" Netrins are genetically conserved across nematode worms, fruit flies, frogs, mice, and humans. Structurally, netrin resembles the extracellular matrix protein laminin.Netrins are chemotropic; a growing axon will either move towards or away from a higher concentration of netrin. Though the detailed mechanism of axon guidance is not fully understood, it is known that netrin attraction is mediated through UNC-40/DCC cell surface receptors and repulsion is mediated through UNC-5 receptors. Netrins also act as growth factors, encouraging cell growth activities in target cells. Mice deficient in netrin fail to form the hippocampal comissure or the corpus callosum.A proposed model for netrin activity in the spinal column of developing human embryos is that netrins are released by the floor plate and then are picked up by receptor proteins embedded in the growth cones of axons belonging to neurons in the developing spinal column. The bodies of these neurons remain stationary while the axons follow a path defined by netrins, eventually connecting to neurons inside the embryonic brain by developing synapses. Research supports that new axons tend to follow previously traced pathways, rather than being guided by netrins or related chemotropic factors.
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