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FoldNucleus: web server for the prediction of RNA
FoldNucleus: web server for the prediction of RNA

... Motivation: To gain insight into how biopolymers fold as quickly as they do, it is useful to determine which structural elements limit the rate of RNA/protein folding. Summary: We have created a new web server, FoldNucleus. Using this server, it is possible to calculate the folding nucleus for RNA m ...
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... • Making an animal with same DNA as a donor • Unfertilized egg cell is replaced by somatic nucleus of an udder • Transcription factors in stem cells are not present in egg cell stage, so fixed determination is un-fixed ...
RACC BIO transcription and translation
RACC BIO transcription and translation

... • The human genome contains 3.2 billion chemical nucleotide bases (A, C, T, and G). • The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. • The total number of genes is estimated at 30,000 • Almost all (99.9%) nucl ...
Protein Synthesis Worksheet
Protein Synthesis Worksheet

... 1. In DNA, adenine binds with ____________ and guanine binds with _____________. 2. In RNA, adenine binds with ____________ and guanine binds with _____________. 3. Transcription takes place in the ________________; translation takes place in the _______________. 4. The building blocks of nucleic ac ...
Camp 1 - UCSC Directory of individual web sites
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... A structural gene that is transcribed into structural gene is made of exons and introns. A regulatory gene that controls transcription; the regulatory gene is not transcribed but has control elements, one of which is the promoter. A promoter is unique to each gene. There is always a sequence of base ...
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... mRNA does not travel to the mitochondria. ...
DNA and Transcription Tutorial
DNA and Transcription Tutorial

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DNA, RNA and Protein Structure Prediction

Describe the central dogma of molecular biology.
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DNA and Transcription Tutorial
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... Following are the steps involved in the processing of pre-mRNA. 1. The addition of the 5’ cap:  Almost all eukaryotic pre-mRNAs are modified at their 5’ends by the addition of a structure called a 5’cap.  This capping consists of the addition of an extra nucleotide at the 5’end of the mRNA and met ...
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... RNA is half the size of DNA, it is the gobetween molecule there are 3 types of RNA 1-messenger RNA: mRNA this is a temporary copy of DNA it contains a copy of gene carried from nucleus------>cytoplasm 2-ribosomal RNA: rRNA along with proteins, this makes up structure of ribosome, which helps in maki ...
apbio ch 17 study guide
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... Many eukaryotic genes code for a set of closely related polypeptides in a process called alternative splicing. ...
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DNA - Doctor Jade Main
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... one end-special triplet of basesanticodon contains complementary sequence of bases to sequence of bases in mRNA recognizes bases in mRNA by applying standard base pairing rules other end is site where amino acid can attach enzyme recognizes both tRNA and its amino acid partner there are at least 32 ...
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Polyadenylation



Polyadenylation is the addition of a poly(A) tail to a messenger RNA The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases. In eukaryotes, polyadenylation is part of the process that produces mature messenger RNA (mRNA) for translation. It, therefore, forms part of the larger process of gene expression.The process of polyadenylation begins as the transcription of a gene finishes, or terminates. The 3'-most segment of the newly made pre-mRNA is first cleaved off by a set of proteins; these proteins then synthesize the poly(A) tail at the RNA's 3' end. In some genes, these proteins may add a poly(A) tail at any one of several possible sites. Therefore, polyadenylation can produce more than one transcript from a single gene (alternative polyadenylation), similar to alternative splicing.The poly(A) tail is important for the nuclear export, translation, and stability of mRNA. The tail is shortened over time, and, when it is short enough, the mRNA is enzymatically degraded. However, in a few cell types, mRNAs with short poly(A) tails are stored for later activation by re-polyadenylation in the cytosol. In contrast, when polyadenylation occurs in bacteria, it promotes RNA degradation. This is also sometimes the case for eukaryotic non-coding RNAs.mRNA molecules in both prokaryotes and eukaryotes have polyadenylated 3'-ends, with the prokaryotic poly(A) tails generally shorter and less mRNA molecules polyadenylated.
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