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No Slide Title
No Slide Title

... Strains 2 &4: Mutation in A and C make the operon constitutive. Strains 3 & 5: Genes B and D encode enzymes. ...
Nucleic Acids B8
Nucleic Acids B8

... In RNA, all of the nucleotides include ribose (single stranded) In RNA, bases are adenine (A) cytosine (C), guanine (G), and uracil (U). (T only in rRNA and DNA) In living cells, three main functional types of RNA, all are directly involved in protein synthesis Messenger RNA (mRNA) Transfer RNA (t ...
Section C: The Control of Gene Expression
Section C: The Control of Gene Expression

... often clustered into an operon with a single promoter and other control elements upstream. • The genes of the operon are transcribed into a single mRNA and translated together ...
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... The rrn16 target site mutations are recessive, and were 100-fold less efficient than the currently used dominant aadA gene. Streptomycin resistance encoded in the rps12 ribosomal protein gene was also included in an early vector. The neo (aph(3')IIa) gene encodes neomycin phosphotransferase II [NPTI ...
WIMM PI Curriculum Vitae Personal Data Name Tudor Alexandru
WIMM PI Curriculum Vitae Personal Data Name Tudor Alexandru

... Every cell within our body carries the same genetic information, yet following iterative developmental transitions hundreds of morphologically and functionally distinct cell types are generated. At the foundation of this fascinating cellular diversification, lies a milieu of finely orchestrated and ...
Molecular Biology Fourth Edition
Molecular Biology Fourth Edition

... Certain DNA Sequences Adopt Unusual Structures • Other sequence-specific DNA structures have been detected, within larger chromosomes, that may affect the function and metabolism of the DNA segments in their immediate vicinity. • For example, certain repetitive sequences can bend the DNA helix in a ...
Monohybrid Crosses
Monohybrid Crosses

... Codons are made up of 3 nitrogen bases, so they look like this: base + base + base = codon (Ex. ACG = a codon) When you read one codon at a time it can be used to determine which amino acid (and this determines which protein) each strand of DNA or RNA will code for. Transcription: Changing DNA to RN ...
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Chapter 6: Gene Expression
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... ribosomal RNAs (rRNAs). The molecules involved in translation (mRNA, tRNA, translation factors) are assembled on ribosomes. Each ribosome is comprised of two sub-units—one is small and one is large. There are three binding sites for tRNA and one binding site for mRNA. These binding sites allow compl ...
Relative Gene Expression Workflow
Relative Gene Expression Workflow

... dynamic range of reverse transcription tend to be mass-dependent. So simply testing the normalizer (generally the highest expressed target in one’s study) and one or two targets of varying expression levels is probably adequate. What about testing every sample? Again, this should be unnecessary, if ...
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Dörte Harpke - Lehrstuhl Technische Informatik der MLU Halle
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... Termination codons are recognized by protein release factors, not by aminoacyl-tRNAs. The structures of the class 1 release factors resemble aminoacyl-tRNA-EF-Tu and EF-G. The class 1 release factors respond to specific termination codons and hydrolyze the polypeptide-tRNA linkage. The class 1 relea ...
Engineering Learning in Unicellular Organisms
Engineering Learning in Unicellular Organisms

... patterns of inputs by changing the strengths of their connections (10). They are widely used in a variety of tasks of machine recognition. From the standpoint of a living cell, the closest approximation to a neural network is probably found in the pathways of intracellular signals (11). Multiple rec ...
Features of Hybrids
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... to trans effects, is not related to divergence in transcription factors or chromatin remodeler (expression or seq.) but rather to environment signalers ...
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Teacher-submitted assessment ideas

... Journal question: “Is there a relationship between mutations & evolution?” Worksheet would be given a check plus, check, check minus. Class discussions: (1) what info do you need? (2) Construct #4 Homework: Make a concept map using no more than 10 terms & would be given a CP, C, CM. Concept maps wou ...
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... Practice Problems 6 1. HMG CoA Reductase is an enzyme involved in the biosynthesis of cholesterol. The protein and mRNA sequences were identified before the genomic sequence, and it was determined that the mRNA is 4471 nucleotides long, and encodes a protein of 888 amino acids. During the human geno ...
Highly specific imaging of mRNA in single cells by target RNA
Highly specific imaging of mRNA in single cells by target RNA

... should be designed with none or minor secondary structure. Besides, multiple targeting sites on mRNA can be tested for improving the efficiency of hybridization and amplification. The second factor is the relatively low spatial resolution of amplification-based single-molecule imaging method. To pro ...
Clicker Review-DNAProtein Syn Mutation
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... 1. Bring an amino acid to the ...
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Non-coding RNA



A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.
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