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Foundations of Biology
Foundations of Biology

... Thus it would be wasteful to express all genes all the time By differential expression of genes, cells can respond to changes in the environment Differential expression, allows cells to specialize in multicelled organisms. Differential expression also allows organisms to develop over time. ...
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... directly, shutting themselves down in response to particular chemical clues. • Breaker, Nudler, Yura and Cossart laboratories report that specific RNA sequences can act as environmental sensors of vitamin cofactors (including vitamins B1, B2 and B12) and temperature, which allow them to directly reg ...
RNAi - University of Maryland, College Park
RNAi - University of Maryland, College Park

... along with its use of genome sequence information, has dramatically changed how these tests are done. RNAi is a form of reverse genetics, meaning researchers can systematically pick genes rather than beginning with mutants and then searching for the genes affected. One major advantage of this method ...
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... Antisense RNA leads to translational inhibition ...
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PowerPoint Presentation - Lectures For UG-5
PowerPoint Presentation - Lectures For UG-5

... OF ALL MESSENGER RNAs IN THE CELL There are two major types of strategy currently used for global RNA expression analysis: •The direct sampling of sequences from source RNA populations or cDNA libraries, or from sequence databases derived therefrom. •Hybridization analysis with comprehensive, non-re ...
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... made at ribosomes in the cytoplasm. How do the instructions in DNA get to the site of protein synthesis outside the nucleus? Another type of nucleic acid is responsible. This nucleic acid is RNA, or ribonucleic acid. RNA is a small molecule that can squeeze through pores in the nuclear membrane. It ...
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... After transcription, the messenger RNA molecules are translated into polypeptides. That is, the base sequence of the mRNA is used as a code to construct an entirely different molecule, the polypeptide. The polypeptide is synthesized from N-terminus to C-terminus, based on free -NH2 and -COOH groups ...
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... After transcription, the messenger RNA molecules are translated into polypeptides. That is, the base sequence of the mRNA is used as a code to construct an entirely different molecule, the polypeptide. The polypeptide is synthesized from N-terminus to C-terminus, based on free -NH2 and -COOH groups ...
Name___________ Midterm Review 1. What is an organism? 2
Name___________ Midterm Review 1. What is an organism? 2

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Biochemistry 304 2014 Student Edition TRANSCRIPTION
Biochemistry 304 2014 Student Edition TRANSCRIPTION

... •Understand how RNA are modified post-transcriptionally •Understand how RNAi’s are involved in post-transcription regulation. •Examine the similarities and differences between prokaryotic and eukaryotic transcription. ...
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Non-coding RNA



A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.
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