CHAPTER 14 Vesicular Traffic, Secretion, and Endocytosis
... Phagocytosis: take up whole cell or large particle. non selective actin mediated process, extension of the membrane. marcophage Ion containing protein Pinocytosis: small droplets of extracellular fluid and any material dissolved , nonspecifically Receptor-mediated endocytosis: specific receptor invo ...
... Phagocytosis: take up whole cell or large particle. non selective actin mediated process, extension of the membrane. marcophage Ion containing protein Pinocytosis: small droplets of extracellular fluid and any material dissolved , nonspecifically Receptor-mediated endocytosis: specific receptor invo ...
03_Membrane rest potential. Generation and radiation action
... This allows valinomycin to enter the lipid core of the bilayer, to solubilize K+ within this hydrophobic milieu. Crystal structure (at Virtual Museum of Minerals & Molecules). ...
... This allows valinomycin to enter the lipid core of the bilayer, to solubilize K+ within this hydrophobic milieu. Crystal structure (at Virtual Museum of Minerals & Molecules). ...
Mouse TRAIL R2 / CD262 / TNFRSF10B Protein (His Tag)
... apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNFreceptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with ...
... apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNFreceptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with ...
Experiment 14: Proteins and Denaturing Agents
... disrupt relatively weak forces such as hydrogen bonds and hydrophobic interactions. The most common example is observed in cooking an egg. Heat is also used in sterilization to denature and hence destroy the enzymes in bacteria. Extremes of pH can cause a protein to denature. The R-groups in the ami ...
... disrupt relatively weak forces such as hydrogen bonds and hydrophobic interactions. The most common example is observed in cooking an egg. Heat is also used in sterilization to denature and hence destroy the enzymes in bacteria. Extremes of pH can cause a protein to denature. The R-groups in the ami ...
Final Presentation Abstract Booklet
... These five include: glutamate 216 which is part of the F-G helix, aspartate 301 which is along the I-helix, and phenylalanines 102, 481, and 483. The heme present is responsible for carrying out hydroxylation on substrates. If a drug can fit well into the binding site, it will be metabolized before ...
... These five include: glutamate 216 which is part of the F-G helix, aspartate 301 which is along the I-helix, and phenylalanines 102, 481, and 483. The heme present is responsible for carrying out hydroxylation on substrates. If a drug can fit well into the binding site, it will be metabolized before ...
Name_________________________________________
... ii) Draw Minoxidil as shown above binding in the site. Be sure to consider the interactions between Minoxidil and the side chains when orienting Minoxidil within the binding site. ...
... ii) Draw Minoxidil as shown above binding in the site. Be sure to consider the interactions between Minoxidil and the side chains when orienting Minoxidil within the binding site. ...
Topology of membrane protein
... synthesized proteins in their native membrane? Or: how does the translocon decide which sequences should stay inside the membrane ...
... synthesized proteins in their native membrane? Or: how does the translocon decide which sequences should stay inside the membrane ...
Lecture 3: Protein trafficking between cell compartments The cytosol
... 2. Conformational changes of SNAREs bring the membranes closer together….. ...
... 2. Conformational changes of SNAREs bring the membranes closer together….. ...
Document
... – Preproinsulin (secreted) – Prealbumin (secreted) – Preproinsulin receptor beta subunit (transmembrane) – The pre refers to the signal peptide • A signal peptide pre sequence at the amino terminus of a protein targets polypeptide/ribosome to the ER – 6-13 hydrophobic proteins near the N-terminus – ...
... – Preproinsulin (secreted) – Prealbumin (secreted) – Preproinsulin receptor beta subunit (transmembrane) – The pre refers to the signal peptide • A signal peptide pre sequence at the amino terminus of a protein targets polypeptide/ribosome to the ER – 6-13 hydrophobic proteins near the N-terminus – ...
Cell membrane
... be more precisely described as phospholipids, that is, lipids that feature a phosphate group at one end of each molecule. Phospholipids are characteristically hydrophilic ("water-loving") at their phosphate ends and hydrophobic ("water-fearing") along their lipid tail regions. In each layer of a pla ...
... be more precisely described as phospholipids, that is, lipids that feature a phosphate group at one end of each molecule. Phospholipids are characteristically hydrophilic ("water-loving") at their phosphate ends and hydrophobic ("water-fearing") along their lipid tail regions. In each layer of a pla ...
3 types of protein transport
... defines a function: lys: digest some: body Lysosomes develop from endosomes by fusion with vesicles carrying lysosomal enzymes ...
... defines a function: lys: digest some: body Lysosomes develop from endosomes by fusion with vesicles carrying lysosomal enzymes ...
Glycolipids and Glyc..
... an aliphatic amino acid and X any C-terminal amino acid. Many cytoplasmic proteins associated with cell surface receptors are linked by palmitoyl chains to the membrane. Often, deacylation inactivates the proteins because they are now released from the membrane. G-proteins and kinases are thought to ...
... an aliphatic amino acid and X any C-terminal amino acid. Many cytoplasmic proteins associated with cell surface receptors are linked by palmitoyl chains to the membrane. Often, deacylation inactivates the proteins because they are now released from the membrane. G-proteins and kinases are thought to ...
Experiment title: Structural analysis of a chimeric bacterial α
... retention of anomeric configuration. Together with many other enzymes that work on α-linked glucopyranose-derived substrates, such as α-glucosidases, cyclodextrin glycosyltransferases (CGTases) and pullulanases, they are found in family 13 of the glycoside hydrolase sequence-classification, often te ...
... retention of anomeric configuration. Together with many other enzymes that work on α-linked glucopyranose-derived substrates, such as α-glucosidases, cyclodextrin glycosyltransferases (CGTases) and pullulanases, they are found in family 13 of the glycoside hydrolase sequence-classification, often te ...
Lecture 5
... Subset of turn-lovers. Glycine is special because it is so flexible, so it can easily make the sharp turns and bends needed in a b-turn. Proline is special because it is so rigid; you could say that it is pre-bend for the b-turn. Aspartic acid, asparagine, and serine have in common that they have sh ...
... Subset of turn-lovers. Glycine is special because it is so flexible, so it can easily make the sharp turns and bends needed in a b-turn. Proline is special because it is so rigid; you could say that it is pre-bend for the b-turn. Aspartic acid, asparagine, and serine have in common that they have sh ...
Where can we find disordered proteins?
... although enriched in IDRs, around 20% are in located within ...
... although enriched in IDRs, around 20% are in located within ...
PowerPoint 簡報
... DNA, protein, membrane lipids, cofactor Appropriate reactivity and/or configuration Accessibility-endogenous molecules that are in the vicinity of reactive chemicals or are adjacent to sites where they are formed ex. enzyme responsible for production of reactive metabolites or the adjacent intra ...
... DNA, protein, membrane lipids, cofactor Appropriate reactivity and/or configuration Accessibility-endogenous molecules that are in the vicinity of reactive chemicals or are adjacent to sites where they are formed ex. enzyme responsible for production of reactive metabolites or the adjacent intra ...
Intro-Cell-Physiology
... Transcription - complementary mRNA is made at the DNA gene. Three-base sequences, or triplets, on the DNA specify a particular amino acid. The corresponding three-base sequences on mRNA are called codons. The form is different, but the information is the same. Translation – The mRNA is "decoded" to ...
... Transcription - complementary mRNA is made at the DNA gene. Three-base sequences, or triplets, on the DNA specify a particular amino acid. The corresponding three-base sequences on mRNA are called codons. The form is different, but the information is the same. Translation – The mRNA is "decoded" to ...
Intro Cell Physiolog..
... Transcription - complementary mRNA is made at the DNA gene. Three-base sequences, or triplets, on the DNA specify a particular amino acid. The corresponding three-base sequences on mRNA are called codons. The form is different, but the information is the same. Translation – The mRNA is "decoded" to ...
... Transcription - complementary mRNA is made at the DNA gene. Three-base sequences, or triplets, on the DNA specify a particular amino acid. The corresponding three-base sequences on mRNA are called codons. The form is different, but the information is the same. Translation – The mRNA is "decoded" to ...
Proteins - churchillcollegebiblio
... • Try and incorporate as many key terms from the topic as you can ...
... • Try and incorporate as many key terms from the topic as you can ...
doc Final Exam 2003
... 52. Which of the following statements regarding the import of nuclear encoded proteins into the chloroplast is not true? a) The energy required for protein import is derived from a proton gradient across the inner membrane. b) Proteins are targeted to the chloroplast stroma by a transit peptide loca ...
... 52. Which of the following statements regarding the import of nuclear encoded proteins into the chloroplast is not true? a) The energy required for protein import is derived from a proton gradient across the inner membrane. b) Proteins are targeted to the chloroplast stroma by a transit peptide loca ...
Lec. 25 - Translation 3
... • Are there any potential deficiencies with this model or the data that support it? • How could it be made stronger? ...
... • Are there any potential deficiencies with this model or the data that support it? • How could it be made stronger? ...
The Leucine Binding Fluorescence Analysis of the Leucine Specific
... transport system. These two proteins are nearly identical in tertiary structure and share about 80% of their amino acid content. These periplasmic binding proteins serve as initial receptors of active transport and chemotaxis for many substrates. Although they are very similar in both structure and ...
... transport system. These two proteins are nearly identical in tertiary structure and share about 80% of their amino acid content. These periplasmic binding proteins serve as initial receptors of active transport and chemotaxis for many substrates. Although they are very similar in both structure and ...
Secondary structure prediction
... Helical transmembrane proteins • ~30% of top 100 drugs bind to membrane proteins • Difficult to determine experimentally • But much easier to predict than globular proteins! • TMpred – based on statistical analysis of transmembrane proteins • TMHMM – based on Hidden Markov Model ...
... Helical transmembrane proteins • ~30% of top 100 drugs bind to membrane proteins • Difficult to determine experimentally • But much easier to predict than globular proteins! • TMpred – based on statistical analysis of transmembrane proteins • TMHMM – based on Hidden Markov Model ...
Biochemical Analysis of the Binding Interaction between LanI and its
... Lantibiotics are a group of ribosomally synthesized antimicrobial peptides produced by Gram-positive bacteria. The lantibiotics subtilin and nisin both target lipid II inhibiting bacterial cell wall biogenesis. To protect the cell against their actively secreted product, the lantibiotic producing st ...
... Lantibiotics are a group of ribosomally synthesized antimicrobial peptides produced by Gram-positive bacteria. The lantibiotics subtilin and nisin both target lipid II inhibiting bacterial cell wall biogenesis. To protect the cell against their actively secreted product, the lantibiotic producing st ...
Anthrax toxin
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium, Bacillus anthracis—the causative agent of anthrax. The toxin was first discovered by Harry Smith in 1954. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.