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Medical applications of Terahertz Imaging: a Review of Current
Medical applications of Terahertz Imaging: a Review of Current

... this area. THz technology is well placed to provide the impetus for the development of the next wave of noninvasive biomedical instruments and it is important that biomedical engineers and scientists embrace this technology early in its development. To this end, this paper is an exposition of THz im ...
The optical microscopy with virtual image breaks
The optical microscopy with virtual image breaks

... aperture is very low. It also takes a long time for scanning over a large sample area for a high resolution imaging. The diffraction limit can be also overcome by some other techniques, e.g. with surface-plasmon superlenses2, nanoscale solid-immersion-lens3, and molecular fluorescence microscopy4,5. ...
Rejection of two-photon fluorescence background in
Rejection of two-photon fluorescence background in

... Because two-photon excited fluorescence (TPEF) is dominantly generated by ballistic (unscattered) light, TPEF microscopy maintains high resolution even within scattering media [1, 2, 3]. According to Beer’s law, the proportion of ballistic light arriving at the focus decays roughly exponentially wit ...
Sample pages 1 PDF
Sample pages 1 PDF

... (which in the bright-field model would correspond to the oscillatory region of the phase contrast transfer function). If the magnitude of g has a value lying between the aperture radius and the aperture diameter, there will still be interference in the single overlap regions (see Figure 2–5). Thus i ...
Real-time fiber-based multi-functional spectral- domain optical coherence tomography at 1.3 m μ
Real-time fiber-based multi-functional spectral- domain optical coherence tomography at 1.3 m μ

... Optical coherence tomography (OCT) is an interferometric technique capable of noninvasive high-resolution cross-sectional imaging by measuring the intensity of light reflected from within tissue [1]. Since the technique is non-contact and provides images similar in scale and geometry to histology, i ...
Unwrapping Hartman-Shack Images from Highly Aberrated Eyes
Unwrapping Hartman-Shack Images from Highly Aberrated Eyes

... To extend the dynamic range of HartmanShack wavefront sensor using B-spline based extrapolation • The results: The dynamic range of a typical HS sensor increases 3.5 to 13 times compared with a simple unwrapping algorithm ...
Visible Wavelength Fiber Bragg Grating Arrays for
Visible Wavelength Fiber Bragg Grating Arrays for

... Biomedical researchers have shown that laser induced autofluorescence at 500 to 800 nm can detect cancer in unstained tissue [2]. Existing technologies have not combined sufficient spatial, spectral, and temporal resolution in one instrument. Spectrometer acquisition speeds are not fast enough to ge ...
OCS`08
OCS`08

... tations and discussions of their applications. Cross disciplinary applications will be in the main line. Contributions are welcomed from Industrial Companies as well as and from Academic Research and papers should focus on integration into systems rather than just individual component descriptions. ...
Resolution [from the New Merriam-Webster Dictionary, 1989 ed.]: 3 resolve
Resolution [from the New Merriam-Webster Dictionary, 1989 ed.]: 3 resolve

... [from the New Merriam-Webster Dictionary, 1989 ed.]: resolve v : 1 to break up into constituent parts: ANALYZE; 2 to find an answer to : SOLVE; 3 DETERMINE, DECIDE; 4 to make or pass a formal resolution resolution n : 1 the act or process of resolving 2 the action of solving, also : SOLUTION; 3 the ...
Quasi-3D plasmonic coupling scheme for near-field optical lithography and imaging Y W
Quasi-3D plasmonic coupling scheme for near-field optical lithography and imaging Y W

... the sample being scanned because their resonance is usually detuned by the change of sample properties at their close proximity. Another widely used approach is to use nanoscale objects, such as nanoparticles or surface apexes, to localize and produce an intense electromagnetic hotspot for lithograp ...
Lecture 18
Lecture 18

... microscope can be characterized by the modulation transfer function (MTF) • MTF is measurement of microscope's ability to transfer contrast from the specimen to the image plane at specific resolution. • Incorporates resolution and contrast into one specification ...
Edge-enhanced imaging with polyvinyl alcohol/acrylamide photopolymer gratings 1510
Edge-enhanced imaging with polyvinyl alcohol/acrylamide photopolymer gratings 1510

... for image processing operations in imaging systems.1 – 4 Bragg diffraction offers unique properties such as wavelength and angular selectivity5; the latter is responsible for the image processing applications reported with AOLMs. However, when programmability of AOLMs was not needed, a wide variety ...
Total 3D imaging of phase objects using defocusing microscopy
Total 3D imaging of phase objects using defocusing microscopy

... index (χ)23 . All values are shown in Table 1 and are in accordance with those reported by other techniques21,24 . The DM 3D imaging method is independent of the chosen reference system, and thus, it can be efficiently used to image red blood cells which are flowing through a glass capillary or a mi ...
Why Optical Images are Easier to Understand Than Radar Images
Why Optical Images are Easier to Understand Than Radar Images

... However, the high resolution of radar image does not mean the resolving ability for targets is high. We may have the same experience that the optical image is much easy to understand than radar image even if it has less resolution. A simple and frank explanation is due to the wavelengths of optical ...
Harnessing a Quantum Design Approach for Making Low
Harnessing a Quantum Design Approach for Making Low

... but they use materials with negative dielectric responses, and they absorb much of the light in a way that seriously degrades both the resolution and brightness of the image. Here we demonstrate an alternative “quantum metamaterials” (QM) approach that uses materials structured at the nanoscale, i.e ...
Microscopes
Microscopes

... beam can be adjusted without affecting the size of the illuminated field ...
Lab 2: Abbe Theory of Imaging
Lab 2: Abbe Theory of Imaging

... Carry out experiments in sequence with square mesh object as shown in Table 2. Place the square mesh in vertical orientation. Mark the locations of the Fourier image dots which are on the x- and y-axis with a white paper pasted on an index card. These locations will be useful to make various spatial ...
Partially Coherent Image Formation Theory for X
Partially Coherent Image Formation Theory for X

... enabled development of short wavelenth focusing elements and significantly improved the spatial resolution [4–9]. In the soft x-ray spectral region, samples as small as a few tens of nanometers can be resolved using micro zone-plates (MZP) as the objective lens [3]. In addition to conventional x-ray ...
Enhanced visualization of choroidal vessels using ultrahigh
Enhanced visualization of choroidal vessels using ultrahigh

... exposure. Thus by using higher incident power at longer wavelengths the sensitivity of ophthalmic OCT is improved by 5.2 dB. In addition, a recent study has shown that imaging biological tissue at central wavelengths close to 1000 nm provides the advantage of minimal OCT axial resolution degradation ...
Imaging complex structures with diffuse light
Imaging complex structures with diffuse light

... a result many accept that anatomically accurate DOT images cannot be reconstructed. Accordingly, the emphasis in DOT has been on functional imaging, and on multi-modality imaging, in which simultaneously acquired MRI or CT images are used to provide anatomical detail [4]. It has been suggested that ...
pdf.file
pdf.file

... cordance with the reversibility principle of linear optics, as derived from Fermat’s principle. There are significant computational savings in neglecting those rays which after reflection from the target, do not enter the camera’s acceptance cone or aperture. In the second data set there are six rec ...
Noniterative Exact Solution to the Phase Problem in Optical Imaging Implemented with Scanning Probe Microscope.
Noniterative Exact Solution to the Phase Problem in Optical Imaging Implemented with Scanning Probe Microscope.

... As is well-known, the basis for obtaining superresolution is multiple images.20 This of course can be obtained in a cumbersome way by moving the sample, which would require the accurate verification of the exact sample movement. This could be done in our method by the presence of an online AFM. Howev ...
Label-free super-resolution imaging of adenoviruses by submerged
Label-free super-resolution imaging of adenoviruses by submerged

... Lin Li1, Wei Guo1, Yinzhou Yan1, Seoungjun Lee1 and Tao Wang2 Because of the small sizes of most viruses (typically 5–150 nm), standard optical microscopes, which have an optical diffraction limit of 200 nm, are not generally suitable for their direct observation. Electron microscopes usually requir ...
Digital X-Ray Imaging - Experimental Elementary Particle Physics
Digital X-Ray Imaging - Experimental Elementary Particle Physics

... means that it is critical to get the exposure right and even then parts of the image will show reduced contrast. Moreover, the detective quantum efficiency (DQE) of the system only has its highest value in the regions where the film gamma is high. In the high and low density regions of the image the D ...
Optimal wavelength for ultrahigh-resolution optical
Optimal wavelength for ultrahigh-resolution optical

... and a decrease in resolution when 800 nm or 1.3 µm light sources are used for OCT imaging of biological tissues. Figure 2 shows the calculated broadening of the autocorrelation function due to nonzero dispersion with Eq. (1). The horizontal axis shows OCT resolution which is determined by the sourc ...
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Preclinical imaging

Preclinical imaging is the visualization of living animals for research purposes, such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in animals responding to physiological or environmental changes. Imaging modalities that are non-invasive and in vivo have become especially important to study animal models longitudinally. Broadly speaking, these imaging systems can be categorized into primarily morphological/anatomical and primarily molecular imaging techniques. Techniques such as high-frequency micro-ultrasound, magnetic resonance imaging (MRI) and computed tomography (CT) are usually used for anatomical imaging, while optical imaging (fluorescence and bioluminescence), positron emission tomography (PET), and single photon emission computed tomography (SPECT) are usually used for molecular visualizations.These days, many manufacturers provide multi-modal systems combining the advantages of anatomical modalities such as CT and MR with the functional imaging of PET and SPECT. As in the clinical market, common combinations are SPECT/CT, PET/CT and PET/MR.
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