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Genetically Engineered Probiotics
Genetically Engineered Probiotics

... commensal bacteria. Genetically engineered probiotics can be used to treat inflammatory bowel disorders such as Crohn's disease, ulcerative colitis, as well as other disorders that result from an overactive immune system. Genetically modified (GM) probiotics are also used as food additives to contro ...
Univ.-Prof. Dr. med. Britta Siegmund
Univ.-Prof. Dr. med. Britta Siegmund

... Award from the „Harvard-Munich-Alliance“ for Medical Education Scientific Focus Major interest of our group is to translate clinical findings of patients with inflammatory bowel diseases to the bench and vice versa with the ultimate goal to contribute to the understanding of the disease pathways as ...
Antibiotic treatment of Crohn`s Disease: Does it Work?
Antibiotic treatment of Crohn`s Disease: Does it Work?

...  Azithromycin 7.5-10 mg /kg /day 5 days a week (max 500mg)+ Metronidazole 15-20 mg/kg daily (max 1000 mg)  Azithromycin 7.5-10 mg /kg /day 3 days a week + Metronidazole 15-20 mg/kg daily ...
behçet`s disease
behçet`s disease

... Being Positive in Life/Being Negative in Life Positive/Negative Support of Their Families Consciousness/Lack of Consciousness of the People Around Them Accepting the Disease/Failing to Accept the Disease Getting Used to the Disease/Failing to Get Used to the Disease Thinking Positively/Negatively Ab ...
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Slide 1

... Obstetrician: ...
Uzun Süreli Periton Dializinde Malnutrisyon Prevelansındaki Neden
Uzun Süreli Periton Dializinde Malnutrisyon Prevelansındaki Neden

... 2007 Dedeoglu,Sundel . Rheum Dis P Clin N Am ...
3 HORMONES from SMALL INTESTINE
3 HORMONES from SMALL INTESTINE

... feces in the rectum : pressure of rectum   reflex of defecation problems : constipation (absorption >>) diarrhea (absorption <<) ...
A Potent Goat Milk Probiotic Formula
A Potent Goat Milk Probiotic Formula

... lactose tolerance, seasonal allergies ...
Pharmaceutical guidelines of patients with pathology of digestive
Pharmaceutical guidelines of patients with pathology of digestive

...  Secretory - occurs when the body is releasing water into the bowel when it's not supposed to. Many infections, drugs, and other conditions cause secretory diarrhea. ...
Fecal Microbiota Transplantation
Fecal Microbiota Transplantation

... • Transfer of stool and bacteria from the colon of a healthy person to the colon of a person ill with a CDI ...
Inflammatory CNS disease
Inflammatory CNS disease

... Treatment of inflammatory CNS disease depends on the primary cause. In case of infectious disease, treatment consists mainly of antibiotic or antifungal medications. Unfortunately we do not have specific treatment for viral infections. In case of noninfectious (pathogen-free inflammatory) disease, t ...
Rheumatoid Arthritis
Rheumatoid Arthritis

... • AB’s directed against nuclear material: • Detection is via indirect immunofluorescence • ANA with titers > 1:40 considered positive ...
Multiple Sclerosis Is an Inflammatory T-Cell–Mediated - Direct-MS
Multiple Sclerosis Is an Inflammatory T-Cell–Mediated - Direct-MS

... Thus, the EAE model replicates both the inflammatory and degenerative stages of the disease. Experimental allergic encephalomyelitis is not an exact model of MS because not all treatments that are effective in EAE are effective in MS, eg, anti–tumor necrosis factor therapy. Also, there are paradoxic ...
traumeric - Ortho Molecular Products
traumeric - Ortho Molecular Products

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1 World-leading Inflammatory Bowel Disease Clinical
1 World-leading Inflammatory Bowel Disease Clinical

... development of EG-10 for the treatment of ulcerative colitis. The newly appointed Clinical Advisors are Drs. Brian Feagan, Geert DʼHaens and Richard Fedorak. They join Dr. Scott Plevy, who has served as a Scientific Advisor to the Company since 2008, to form the Clinical Advisory Board. This group o ...
F2005B02526 F2005B02526
F2005B02526 F2005B02526

... For the purposes of this Statement of Principles: “a dura mater graft” means a surgical procedure where a dura mater graft from a human donor is used; “blood products” means material extracted from human blood; “bovine spongiform encephalopathy infection” also known as “mad cow disease”, means a dis ...
Pentasa, Asacol, Salofalk - Oxford University Hospitals
Pentasa, Asacol, Salofalk - Oxford University Hospitals

... they have a special coating which is not destroyed by acids in the stomach) tablets. They should be swallowed whole and not chewed. You should not take indigestion remedies at the same time as Asacol® tablets. Asacol® is also available as suppositories and foam enemas. Salofalk® comes as yellow 250m ...
The_Gastrointestinal_Tract
The_Gastrointestinal_Tract

... spreads until entire colon is involved ...
The use of Trichuris suis and other helminth therapies to treat
The use of Trichuris suis and other helminth therapies to treat

... inhibiting dysregulated inflammatory responses (Weinstock et al. 2005). For parasites of humans and animals that rely on vectors or on sexual contact for transmission, infection must not terminate before the occurrence of the crucial event that completes its life cycle (Gupta 2005). Multiple layers ...
Ankylosing Spondylitis or Crohn`s Disease?
Ankylosing Spondylitis or Crohn`s Disease?

... Yersinia spp., is HLA-B27 negative, the clinical picture is not dominated by fever or abdominal pain, and the aphtous ulcers involve the entire small bowel, not only the ileum. For these reasons, infection with Yersinia spp. is unlikely to explain this patient’s presentation. Reactive arthritis may ...
Protein-Losing Gastro- Enteropathy (PLGE)
Protein-Losing Gastro- Enteropathy (PLGE)

... – Mucoid, and/or bloody stool associated with erythematous, inflammatory colonic polyps covered by a cap of fibrinopurulent mucous. – Most common in women, during the fifth decade. However, it has been described in men and women ranging from 12 to 76 years of age. – Weeks to months of mucoid and blo ...
NAME OF LABORATORY: The Research Center for Digestive Tract
NAME OF LABORATORY: The Research Center for Digestive Tract

... PI: Prof. Iris Dotan MD, PhD Research Director at the Division of Digestive Diseases: Prof. Zamir Halpern MD Research Center Manager: Dr. Chen Varol PhD Research Objectives: ...
Anti-food polysaccharide antibody formation in Inflammatory
Anti-food polysaccharide antibody formation in Inflammatory

... Abstract of PhD project Inflammatory bowel disease (IBD) is a chronic inflammatory disease affecting approximately 400 people per 100K populations in UK, which burdens the NHS with £720 million per annum (British Society of Gastroenterology, 2009). It has been shown that IBD patients produce an abno ...
Evaluating Hum Gut Microbiota and Microbe
Evaluating Hum Gut Microbiota and Microbe

... acquired during the first three years of life. stable inhabitants for decades. decades to manifest clinical symptoms ...
Wegener`s Granulomatosis
Wegener`s Granulomatosis

... of 20 patients with diffuse alveolar hemorrhage (DAH) and ANCA-associated small vessel vasculitis y All patients underwent daily full plasma volume plasma exchange until DAH ...
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Ulcerative colitis



Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon. The disease is a type of colitis, which is a group of diseases that cause inflammation of the colon, the largest section of the large intestine, either in segments or completely. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset. IBD (Crohn's disease (CD) and ulcerative colitis (UC)) is often confused with irritable bowel syndrome (IBS).Ulcerative colitis has much in common with Crohn's disease, another form of IBD, but what sets it apart from Crohn's disease is that ulcerative colitis, as its name suggests, only affects the colon and rectum, leaving the rest of the gastrointestinal tract unscathed, while Crohn's disease can affect the whole GI tract from mouth to anus. Also, surgical removal of the colon and rectum cures ulcerative colitis, which actually means the disease does not recur after surgery, unlike Crohn's disease, which has a tendency to recur after surgery to remove the abnormal part of the bowel and connect the healthy ends. Ulcerative colitis is an intermittent disease, with periods of exacerbated symptoms, and periods that are relatively symptom-free. Although the symptoms of ulcerative colitis can sometimes diminish on their own, the disease usually requires treatment to go into remission. Ulcerative colitis has an incidence of 1 to 20 cases per 100,000 individuals per year, and a prevalence of 8 to 246 per 100,000 individuals.The disease is more prevalent in northern countries of the world, as well as in northern areas of individual countries or other regions. Rates tend to be higher in more affluent countries, which may indicate the increased prevalence is due to increased rates of diagnosis. It may also indicate that an industrial or Western diet and lifestyle increases the prevalence of this disease, including symptoms which may or may not be related to ulcerative colitis. Although UC has no known cause, there is a presumed genetic component to susceptibility. The disease may be triggered in a susceptible person by environmental factors. Dietary modification may reduce the discomfort of a person with the disease.Like Crohn's disease, ulcerative colitis is both classed as and managed as an autoimmune disease. Management is with anti-inflammatory drugs, immunosuppression, and biological therapy targeting specific components of the immune response. Colectomy (partial or total removal of the large bowel through surgery) is occasionally necessary if the disease is severe, does not respond to treatment, or if significant complications develop. A total proctocolectomy (removal of the entirety of the large bowel and rectum) can cure ulcerative colitis as the disease only affects the large bowel and rectum and does not recur after removal of the latter. While extra-intestinal symptoms will remain, complications may develop.
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