Metabolic Wiring We are introducing a newly discovered cell
... We are introducing a newly discovered cell-cell communication method to iGEM, called metabolic wiring. This uses intermediate metabolites of a pathway as the signalling molecules. Our aim is to establish this new orthogonal signalling mechanism for the synthetic biology community. To demonstrate its ...
... We are introducing a newly discovered cell-cell communication method to iGEM, called metabolic wiring. This uses intermediate metabolites of a pathway as the signalling molecules. Our aim is to establish this new orthogonal signalling mechanism for the synthetic biology community. To demonstrate its ...
basic chemistry of atoms and molecules
... These atoms can be bonded together to form molecules important to the body called monomers. Monomers are the basic building blocks used to create even larger molecules called polymers. Some common monomers are glucose, glycerol and fatty acids, amino acids, and nucleotides. These monomers can ...
... These atoms can be bonded together to form molecules important to the body called monomers. Monomers are the basic building blocks used to create even larger molecules called polymers. Some common monomers are glucose, glycerol and fatty acids, amino acids, and nucleotides. These monomers can ...
"Allosteric Activation of Kinases: Design and Application of RapR
... sequence to a protein kinase with known structure. Due to the high degree of conservation, this can be accomplished even by comparison with unrelated kinases. By comparing the amino acid sequences of the tyrosine kinase Src and the serine/threonine kinase p38, we could readily identify the site for ...
... sequence to a protein kinase with known structure. Due to the high degree of conservation, this can be accomplished even by comparison with unrelated kinases. By comparing the amino acid sequences of the tyrosine kinase Src and the serine/threonine kinase p38, we could readily identify the site for ...
Cell Structure - PLC-METS
... All living things are made of cells. Some organisms or living things consist of one cell. Other organisms, such as humans, are made of many different types of cells. Protists, bacteria and some fungi are one-celled organisms. A pond water sample will most likely contain many examples of protists. On ...
... All living things are made of cells. Some organisms or living things consist of one cell. Other organisms, such as humans, are made of many different types of cells. Protists, bacteria and some fungi are one-celled organisms. A pond water sample will most likely contain many examples of protists. On ...
Plant Cells Contain Two Functionally Distinct
... al., 1992) cells. The processed mature form of aleurain colocalized with vacuolar enzyme markers in cell fractionation experiments (Holwerda et al., 1992). The enzymes responsible for processing proaleurain in barley aleurone cells have an acidic pH optimum (Holwerda et al., 1990), and aleurain puri ...
... al., 1992) cells. The processed mature form of aleurain colocalized with vacuolar enzyme markers in cell fractionation experiments (Holwerda et al., 1992). The enzymes responsible for processing proaleurain in barley aleurone cells have an acidic pH optimum (Holwerda et al., 1990), and aleurain puri ...
Chapter 3 - Slothnet
... folding results in a macromolecule with specific three-dimensional shape. The outer surfaces present functional groups that can interact with other molecules. ...
... folding results in a macromolecule with specific three-dimensional shape. The outer surfaces present functional groups that can interact with other molecules. ...
Review The Role of Laminin in Embryonic Cell Polarization and
... The processes of endodermal and ectodermal differentiation can be recapitulated in cultured embryoid bodies (EBs) derived from suspended aggregates of mouse embryonic stem (ES) cells (Figures 2 and 3). After 2 days of culturing, the outer cells of the EB become flat in shape and begin to resemble th ...
... The processes of endodermal and ectodermal differentiation can be recapitulated in cultured embryoid bodies (EBs) derived from suspended aggregates of mouse embryonic stem (ES) cells (Figures 2 and 3). After 2 days of culturing, the outer cells of the EB become flat in shape and begin to resemble th ...
metabolic regulation
... in which signals arriving at a cell trigger some change in cell activity e.g. responses to other hormones and growth factors; perception of sight, smell, taste; control of the cell cycle. ...
... in which signals arriving at a cell trigger some change in cell activity e.g. responses to other hormones and growth factors; perception of sight, smell, taste; control of the cell cycle. ...
posterior pituitary
... does not work in humans. So for many years, the only source of GH for therapy was that extracted from the glands of human cadavers. This supply was shut off when several patients died from a rare neurological disease attributed to ...
... does not work in humans. So for many years, the only source of GH for therapy was that extracted from the glands of human cadavers. This supply was shut off when several patients died from a rare neurological disease attributed to ...
Understanding the role of cholesterol in cellular biomechanics and
... Abstract. Cholesterol is an important component of cell plasma membrane. Due to its chemical composition (long rigid hydrophobic chain and a small polar hydroxyl group), it fits most of its structure into the lipid bilayer, where its steroid rings are in close proximity and attracted to the hydrocar ...
... Abstract. Cholesterol is an important component of cell plasma membrane. Due to its chemical composition (long rigid hydrophobic chain and a small polar hydroxyl group), it fits most of its structure into the lipid bilayer, where its steroid rings are in close proximity and attracted to the hydrocar ...
The Golgi Apparatus - Global Science Books
... be exported to the Golgi apparatus, and then have to be retrieved. In addition, certain membrane proteins such as SNAREs reach the Golgi as part of the transport machinery between ER and Golgi, and must therefore be recycled to the ER to maintain efficient transport of proteins out of the ER. A mech ...
... be exported to the Golgi apparatus, and then have to be retrieved. In addition, certain membrane proteins such as SNAREs reach the Golgi as part of the transport machinery between ER and Golgi, and must therefore be recycled to the ER to maintain efficient transport of proteins out of the ER. A mech ...
Gene Section PTPRJ (protein tyrosine phosphatase, receptor type, J)
... (FNIII) repeats, contains 34 potential N-linked glycosylation sites and it was found glycosylated in seven asparagine residues by mass spectrometry (Liu et al., 2005; Chen et al., 2009). DEP-1 can dimerize (binding site 972-996) through the transmembrane domain (Chin et al., 2005) but it is unclear ...
... (FNIII) repeats, contains 34 potential N-linked glycosylation sites and it was found glycosylated in seven asparagine residues by mass spectrometry (Liu et al., 2005; Chen et al., 2009). DEP-1 can dimerize (binding site 972-996) through the transmembrane domain (Chin et al., 2005) but it is unclear ...
A Rab4-like GTPase in Dictyostelium discoideum
... 1992; Ruscetti et al., 1994). These small vesicles enter larger vacuoles that are acidified and contain acid hydrolases (Rodriguez-Paris et al., unpublished data; Padh et al., 1993; Aubry et al., 1993; Cardelli et al., 1989). Fluid-phase components then enter larger post-lysosomal compartments of ne ...
... 1992; Ruscetti et al., 1994). These small vesicles enter larger vacuoles that are acidified and contain acid hydrolases (Rodriguez-Paris et al., unpublished data; Padh et al., 1993; Aubry et al., 1993; Cardelli et al., 1989). Fluid-phase components then enter larger post-lysosomal compartments of ne ...
binding domains demonstrated in a plant split
... proteins are synthesized as pre-proteins with a cleavable Nterminal transit peptide. They are recognized and translocated via the action of protein complexes at the outer and inner membrane of the organelle, designated Toc (translocon at the outer envelope membrane) and Tic (translocon at the inner ...
... proteins are synthesized as pre-proteins with a cleavable Nterminal transit peptide. They are recognized and translocated via the action of protein complexes at the outer and inner membrane of the organelle, designated Toc (translocon at the outer envelope membrane) and Tic (translocon at the inner ...
Биохимия жидкостей полости рта
... • The content of calcium ions in the saliva is in the range of 0,75 – 3,0 mmol/l (as in plasma). Calcium can be present in ionized (Ca2 +) or related with protein forms. • Phosphates are in the saliva in the form of free ions hydrogenphosphate and dihydrogenphosphate, which accounts for 70 - 95% of ...
... • The content of calcium ions in the saliva is in the range of 0,75 – 3,0 mmol/l (as in plasma). Calcium can be present in ionized (Ca2 +) or related with protein forms. • Phosphates are in the saliva in the form of free ions hydrogenphosphate and dihydrogenphosphate, which accounts for 70 - 95% of ...
Viral protein targeting to the cortical endoplasmic reticulum is
... various strategies to spread from one cell to another. Animal viruses commonly use vesicular transport machineries in the se cretory and endocytosis/exocytosis pathways for entry and exit (Pelkmans et al., 2001; Sieczkarski and Whittaker, 2002; Smith and Helenius, 2004; Greber and Way, 2006). Howev ...
... various strategies to spread from one cell to another. Animal viruses commonly use vesicular transport machineries in the se cretory and endocytosis/exocytosis pathways for entry and exit (Pelkmans et al., 2001; Sieczkarski and Whittaker, 2002; Smith and Helenius, 2004; Greber and Way, 2006). Howev ...
L egionella pneumophila
... micro-organisms in longitudinal and transverse arrangement to the plane of fracture (Fig. 1 a). In these colonies, bacterial cells more than 20 pm in length were common (Fig. 1 b). The major fracture plane occurred through the hydrophobic region of the plasma (inner) membrane revealing both the prot ...
... micro-organisms in longitudinal and transverse arrangement to the plane of fracture (Fig. 1 a). In these colonies, bacterial cells more than 20 pm in length were common (Fig. 1 b). The major fracture plane occurred through the hydrophobic region of the plasma (inner) membrane revealing both the prot ...
Accompanying protein alterations in malignant cells with a
... possible contribution of Mcl-1 protein to support a previously determined drug-resistance phenotype and promote survival, we determined its basal level of expression in each ovarian cell line and compared it with that observed after drug treatment. Presently, an intense interest exists in the cytosk ...
... possible contribution of Mcl-1 protein to support a previously determined drug-resistance phenotype and promote survival, we determined its basal level of expression in each ovarian cell line and compared it with that observed after drug treatment. Presently, an intense interest exists in the cytosk ...
File
... membrane (causing an action potential if a threshold is reached) Once it has released from the receptor, an enzyme called acetylcholinesterase breaks down into choline and acetate Choline is reabsorbed back into the pre-synaptic neuron where it is combined with another acetyl group to form anoth ...
... membrane (causing an action potential if a threshold is reached) Once it has released from the receptor, an enzyme called acetylcholinesterase breaks down into choline and acetate Choline is reabsorbed back into the pre-synaptic neuron where it is combined with another acetyl group to form anoth ...
Bioinformatics in Brief This week: DB for structures Structure
... comparison of proteins in the PDB, and to create a hierarchical clustering of families. • FSSP=Fold classification based on StructureStructure alignment of Proteins ...
... comparison of proteins in the PDB, and to create a hierarchical clustering of families. • FSSP=Fold classification based on StructureStructure alignment of Proteins ...
GOALS FOR LECTURE 9:
... Phosphofructokinase (PFK) catalyzes the rate-limiting step in glycolysis and is the most important control point. It is also the first irreversible step that is unique to the glycolytic pathway; G6P can be used as an intermediate in other pathways including glycogen synthesis and the pentose phospha ...
... Phosphofructokinase (PFK) catalyzes the rate-limiting step in glycolysis and is the most important control point. It is also the first irreversible step that is unique to the glycolytic pathway; G6P can be used as an intermediate in other pathways including glycogen synthesis and the pentose phospha ...
Insilico Studies on Taste Receptor Gene (Tas2r38) and Tas2r38
... functions based on the observation that the TAS2R genes are expressed at various extra-oral sites.( W. MEYERHOF)Various TAS2Rs show quite specific agonist profiles, like ptc & prop, have certain chemical substructures in common. In the formation of bitterness receptors, the human body uses “blueprin ...
... functions based on the observation that the TAS2R genes are expressed at various extra-oral sites.( W. MEYERHOF)Various TAS2Rs show quite specific agonist profiles, like ptc & prop, have certain chemical substructures in common. In the formation of bitterness receptors, the human body uses “blueprin ...
Signal transduction
Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.