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Mary Pilson
Mary Pilson

... 2) Explain why compartmentalization is important in eukaryotic cells and give two examples. ...
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Special Guest Speaker Dr. Christopher Colbert

... a few, such as biphenyl 2,3-dioxygenase from Pandoraea pnomenusa B-356 (BPDO), can potently degrade a large variety of PCB congeners. We have elucidated the structural basis for the broad PCB oxidation properties of BPDO, based on information from our structural studies combined with activity assays ...
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... lines derived from different origins and is far less harmful for HUVEC cells (Human Umbilical Vein Endothelial Cells). FC selectively induces apoptosis in cancer cells by stimulating the TRAIL pathway. The TRAIL pathway does probably not include the primary target of FC. To identify the FC receptor ...
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... contribute to the cancer. • Transformation into a malignant cell results from abnormalities in the normal growth regulatory program caused by gain-of- function mutation in proto-oncogens. • However, loss-of-function mutation also must occur in the tumor suppressor genes for full transformation to a ...
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Cell Communication
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... acts as gate when receptor changes shape When signal molecule binds as a ligand to receptor, gate allows specific ions, such as Na+ or Ca2+, through a channel in receptor ...
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... gene expression c. the process where DNA wraps around histones to form a nucleosome d. the process of replication of RNA prior to cell division 22. Regarding second messengers, which is true? a. are substances that interact with first messengers outside cells b. are hormones secreted by cells in res ...
CELL SIGNALLING
CELL SIGNALLING

... Signaling through enzyme liked cell-surface receptors Receptor tyrosine kinases and non-receptor tyrosine kinases ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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