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Peroxiredoxin-controlled G-CSF signalling at the endoplasmic
Peroxiredoxin-controlled G-CSF signalling at the endoplasmic

... defence against bacteria. In non-phagocytic cells, H2O2 has long been considered as an unwanted by-product of cell metabolism, potentially hazardous because of the damaging effects on proteins, lipids, carbohydrates and nucleic acids (Rhee, 2006; Rhee et al., 2005b). There is increasing evidence tha ...
Looking for DNA modifications in Parkinson`s (PDF
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... There is a second type of DNA modification that may be involved called histone modification. Our cells contain the same DNA – a full score of instructions for every cell in our bodies, yet our cells are not all the same. Histone modifications help make sure the right parts of the DNA are active in t ...
Cooke Zeeman 1976 Wavefront model for morphogenesis
Cooke Zeeman 1976 Wavefront model for morphogenesis

... whole body pattern and (b) approximately normal in abnormally small bodies. Naively, a mechanism for achieving this would be to have the preo semitic cells, which are two longitudinal tracts down the body axis, responsive to a particular regular succession of values of the p.i. variable or body grad ...
A Small, Novel Protein Highly Conserved in Plants and Animals
A Small, Novel Protein Highly Conserved in Plants and Animals

... primordia, and roots. Notably, when leaf tissue was separated into dividing, expanding, differentiating, and mature regions, RNA levels were highest in expanding leaf tissue (the stage when cell lobing occurs) and were extremely low in mature leaf tissue. RNA levels were also analyzed in brk1-mum1 a ...
ViewQC_red_cell_serology
ViewQC_red_cell_serology

...  Must comply with the standards laid down for potency (titer and avidity) and specificity  New reagents should not be introduced into routine work until internal QC testing have confirmed that they are satisfactory  Should be clearly labeled with : o Batch number o Expiry date o Storage temperatu ...
The Plasma Membrane and Membrane Potential
The Plasma Membrane and Membrane Potential

... • K+ more concentrated in the ICF – If K+ diffuses out, the ICF becomes more negative – K+ attracted by negative charge, moves into cell – Equilibrium is reach, membrane potential will equal -90mV ...
Mycotoxins reveal connections between plants and animals
Mycotoxins reveal connections between plants and animals

... diseases of the immune system (Critchfield and Lenardo, 1995). At the level of scientific interactions, the discovery of the existence and role of programmed cell death in healthy and diseased tissue has led to new collaborations among cell biologists, geneticists and pathologists. Although apoptosi ...
Passive vs Active transport
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Metabolic changes during carcinogenesis
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L-form bacteria, cell walls and the origins of life
L-form bacteria, cell walls and the origins of life

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Biological Effects of Electromagnetic Fields
Biological Effects of Electromagnetic Fields

... in marine vertebrates, birds, and mammals [see Adey, 1981, for review]. In vitro studies have reported similar sensitivities for cerebral Ca2+ efflux, and in a wide spectrum of calcium-dependent processes that involve cell membrane functions, including bone-growth, modulation of intercellular commun ...
Signal Transduction and Control of the Cell Cycle in Yeast
Signal Transduction and Control of the Cell Cycle in Yeast

... mutations in organisms or cells by treating them with DNA-damaging substances, then look for cells that can no longer respond to the particular environmental cue. Characterizing the specific proteins that are affected by these mutations gives insights into the components of the entire pathway. One p ...
Biological Effects of Electromagnetic Fields
Biological Effects of Electromagnetic Fields

... in marine vertebrates, birds, and mammals [see Adey, 1981, for review]. In vitro studies have reported similar sensitivities for cerebral Ca2+ efflux, and in a wide spectrum of calcium-dependent processes that involve cell membrane functions, including bone-growth, modulation of intercellular commun ...
Publications de l`équipe
Publications de l`équipe

... In multicellular organisms, distant cells can exchange information by sending out signals composed of single molecules or, as increasingly exemplified in the literature, via complex packets stuffed with a selection of proteins, lipids, and nucleic acids, called extracellular vesicles (EVs; also known ...
Negative Controls of Cell Proliferation: Human
Negative Controls of Cell Proliferation: Human

... is sketchy and full of controversy. Several hypotheses have been proposed and they vary significantly depending on the premises on which they are based. For example, while hypotheses on positively regulated mechanisms rely on the notion that cells are waiting for a signal to trigger their entering t ...
The Differentiation of Contact Cells and Isolation
The Differentiation of Contact Cells and Isolation

Supplemental Figures
Supplemental Figures

... Supplemental Figure 2. ETR capacities and 77K chlorophyll fluorescence measured in wild-type and pgrl1 during transients from moderate to high light performed under two different CO2 concentrations. Wild-type (dark bars) and pgrl1 (white bars) cells were grown photo-autotrophically in 1-L photobiore ...
PDF
PDF

... in mitotic cells by live imaging. The ER was excluded from chromosomes and the central spindle area in control metaphase cells but, strikingly, was closely associated with mitotic chromosomes and the spindle in REEP3/4 knockdown cells (Figure 2A). Moreover, the characteristic ER enrichment at spindl ...
Esponjas calcáreas (clase Calcarea)
Esponjas calcáreas (clase Calcarea)

... suspended particles within the sponge are too large or highly concentrated. However, there are no known nerve structures. However, some sponges may respond to electrical impulses. Percep ti on Ch an n el s: chemical ; electric ...
C9orf72 binds SMCR8, localizes to lysosomes and regulates
C9orf72 binds SMCR8, localizes to lysosomes and regulates

... al., 2013). More specifically, the FLCN-FNIP complex has GTPase activating protein (GAP) activity towards the RagC/D GTPases (Tsun et al., 2013). The major function for the Rag GTPases is not related to membrane traffic. Instead, their best understood function is to recruit mechanistic target of rap ...
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Assessment of Aging in Saccharomyces Cerevisiae Yeast Mutants
Assessment of Aging in Saccharomyces Cerevisiae Yeast Mutants

... division of the cell during budding. Products of oxidative damage such as extrachromosomal rDNA circles accumulate in old cells [16], but they are not passed on to the buds. In stationary cultures of yeast cells, symptoms of aging can be seen in the entire population. In this type of study the main ...
Retroviruses and oncogenes II
Retroviruses and oncogenes II

... of retroviruses might be alley cats of evolution with little importance to human kind. The discovery of cellular s r c and the inference that it gave rise to the oncogene of Rous Sarcoma Virus inspired hope that this narrow view might be wrong (31). If cells contain genes capable of becoming oncogen ...
File - Wk 1-2
File - Wk 1-2

... Lymphatic spread occurs through the lymphatic system where metastases will be drained by and travel through the lymphatic system and can pass on into the haematologic system. This method of spreading is most frequently seen in carcinomas but may also be seen in sarcomas. Addressing the relationship ...
Introduction to Biology - Phillips Scientific Methods
Introduction to Biology - Phillips Scientific Methods

... b. Cilia and flagella – are extensions of eukaryotic cells, and are composed of, and move by, microtubules. Cilia are numerous and short, and flagella occur one or two to a cell and are longer. 1) Cilia and flagella are composed of a core of nine pairs of microtubules arranged in a ring around two s ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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