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video slide - Biology Junction
video slide - Biology Junction

... (a) Cytoplasmic determinants in the egg. The unfertilized egg cell has molecules in its cytoplasm, encoded by the mother’s genes, that influence development. Many of these cytoplasmic determinants, like the two shown here, are unevenly distributed in the egg. After fertilization and mitotic division ...
Retinoic acid-mediated activation of HNF-3a
Retinoic acid-mediated activation of HNF-3a

... stem cells into a new cell type that resembles primitive extraembryonic endoderm in the mouse embryo [4]. Like authentic primitive endoderm, mouse F9 cells are bipotential: further treatment with cAMP-elevating agents leads to the formation of parietal endoderm [5]; aggregation, on the other hand, y ...
Tagging the dead: a bridging factor for Caenorhabditis elegans
Tagging the dead: a bridging factor for Caenorhabditis elegans

... compartment. Nuclear transport and targeting of proteins to primary cilia therefore share common molecular determinants (Fig. 1) and might have evolved from the same ancestral targeting machinery. Many eukaryotic cells develop non-motile, primary cilia that function as cellular ‘antennae’, transduci ...
the cell cycle of symbiotic chlorella
the cell cycle of symbiotic chlorella

... Chlorella algae symbiotic with green hydra did not arrest in G\ when cell division was blocked by host starvation, but appeared to cycle slowly through 5 phase. No distinct S/mitosis peak could be distinguished in algae from 1-day starved hosts, and if host starvation was prolonged, algal DNA conten ...
Cell Membrane Structure - Toronto District Christian High School
Cell Membrane Structure - Toronto District Christian High School

... The shapes of the membrane proteins vary according to their function, and each type of cell has a characteristic arrangement of proteins in its membrane. For example, the membrane of a human red blood cell includes 50 different protein types arranged in a pattern that only other cells from humans wi ...
Ion Transport Defects in Microvillus Inclusion Disease(MVID
Ion Transport Defects in Microvillus Inclusion Disease(MVID

... Associate Professor Pediatrics/Cellular and  Molecular Physiology Yale University School Medicine ...
video slide - Course
video slide - Course

... (a) Cytoplasmic determinants in the egg. The unfertilized egg cell has molecules in its cytoplasm, encoded by the mother’s genes, that influence development. Many of these cytoplasmic determinants, like the two shown here, are unevenly distributed in the egg. After fertilization and mitotic division ...
A protein
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... (c) Attachment to the cytoskeleton and extracellular matrix (ECM) Elements of the cytoskeleton (cell’s internal supports) and the extracellular matrix (fibers and other substances outside the cell) may be anchored to membrane proteins, which help maintain cell shape and fix the location of certain m ...
Grüning et al. The structural basis for inhibition of triosephosphate
Grüning et al. The structural basis for inhibition of triosephosphate

... Cloning, Recombinant TPI expression and purification DNA fragments encoding human TPI were obtained by PCR using the p413GPD-TPI and p413GPDTPIIle170Val plasmids (1) as templates, human TPI Ile170Thr and TPI Lys13Arg alleles were generated by site directed PCR mutagenesis. The DNA fragments were lig ...
Cellular and Genetic Responses of Plants to Sugar Starvation
Cellular and Genetic Responses of Plants to Sugar Starvation

... there is a general starvation response among various bacteria species. For example, Glc- or nitrogen-starved cultures of E. coli exhibit resistance to heat or hydrogen peroxide (Jenkins et al., 1988). The nitrogen-fixing bacterium Rhizobium leguminosarum can survive carbon, nitrogen, and phosphorus ...
Distribution of Lysosomes in Cultured Cells and Ascites Tumor Cells
Distribution of Lysosomes in Cultured Cells and Ascites Tumor Cells

... lysosomes distributed in the periphery of the cytoplasm in the same fashion as in those found in liver cells in vivo. At the periphery of the outgrowth, lysosomes located exclusively in the nuclear hof, or otherwise they scattered evenly throughout the cytoplasm as discrete fine particles. In still ...
Sickle cell anaemia
Sickle cell anaemia

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Notes Sexual - Weiss World of Science

... Sexual reproduction brings non-identical gametes together to form new organism - it occurs in ___ stages: 1. _________ - the process by which gametes are bought together at same place and same time 2. __________ - process by which egg and sperm join to form a new organism 3. __________ - the process ...
the specificity and stability of the triton
the specificity and stability of the triton

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... ∗ These were discovered by Nocard and Roux. The term Mycoplasma was first used by Frank. These are previously known as PleuroPeumonia like organisms. ...
J. Keith Joung, MD, PhD - Massachusetts General Hospital
J. Keith Joung, MD, PhD - Massachusetts General Hospital

Middle East Jeopardy - Central Kitsap Junior High
Middle East Jeopardy - Central Kitsap Junior High

... Traps energy from the sun to make glucose. Chloroplast ...
Fifth dimension of life and the 4/5 allometric scaling law for human
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... a single universal explanation for allometric scalings. But the model has been challenged by some authors (Beuchat, 1997; Dawson, 1998). Dawson (1998) points out that the assumption that capillary dimensions are independent of mammal size is contrary to his early work and to basic cardiovascular des ...
Expression and purification of S100A12 and the V domain of
Expression and purification of S100A12 and the V domain of

... The recombinant cDNA of the RAGE V domain (residues 22–121) was subcloned into the pET-32b (+) vector, which was purchased from Mission Biotech Company. The overexpressed cells were grown in M9 or LB medium until the OD at 600 nm reached 0.7. Then, 1 mM IPTG was added to induce protein expression at ...
Cell structure and functions - formatted
Cell structure and functions - formatted

... resolution microscopes, in particular the electron microscope, internal structure of a wide variety of cells has been now studied. These studies clearly differentiate two basic classes of cells - Prokaryotes and Eukaryotes. The structurally simple prokaryote cells are found among unicellular organis ...
REVIEWS TBP-associated factors (TAF s): multiple, selective
REVIEWS TBP-associated factors (TAF s): multiple, selective

... has been subjected to targeted homologous recombination in mouse embryonic stem cells producing cells deficient in TAFII30 (Ref. 20). The results indicate that TAFII30 is required only for transcription of a subset of genes. In general, higher eukaryotic TAFIIs are distributed ubiquitously, although ...
Sec 16.3 Sexual Reproduction
Sec 16.3 Sexual Reproduction

... before meiosis II starts Meiosis II Prophase II – Metaphase II – Anaphase II – Telophase II Cytokinesis The result is 4 haploid daughter cells. Gametes are made by meiosis, 2 gametes must come together to form a new organism because each gamete only has half of the number of chromosomes. ...
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Genetic Factors That Regulate the Attenuation of the

... be; Srb10-dependent phosphorylation of Msn2 was observed only during the initial period of stress. This stressdependent phosphorylation cannot account for STRE derepression under nonstress conditions in an srb10⌬ strain. In addition, Msn2 was observed to be in the nucleus in less than one-third of u ...
Local interactions shape plant cells
Local interactions shape plant cells

... the scalar nature of turgor is manifested in the form of a small bulge. This weak, bulged domain polarizes the cell as it becomes the focus of sub-cellular activities aimed at reinforcing the weak region. The enlarged cross-sectional view of the bulge shown here reveals that the weak region is follo ...
Role of reactive oxygen species in cell signalling pathways Abstract
Role of reactive oxygen species in cell signalling pathways Abstract

... signalling molecules : they are small, and can diffuse short distances ; there are several mechanisms for their production, some of which are rapid and controllable ; and there are numerous mechanisms for their rapid removal. Work based on the release of ROS by cells which do not have a role in phag ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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