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Integumentary System / Skin
Integumentary System / Skin

... Barrier to keep bacterial, dirt, etc. out Protection against abrasion Contains sensory receptors for touch, temperature, pressure, pain, etc. Temperature regulation via hair, sweat, & amount of ...
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... further, the properties of precursor cells from the forebrain of LIFR-de®cient mice were examined in vitro.23 It was shown that precursors from the forebrains of mice homozygous for the LIFR null mutation (LIFR±/±) failed to generate signi®cant numbers of GFAP-positive cells even after 3 weeks in vi ...
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... ference is the presence of one or several vacuoles, which may take up more than 95% of the volume of the cell [24]. Vacuoles lack internal structure, appearing ‘empty’ under the light or electron microscope (hence their name). In fact, the vacuolar liquid contains salts, sugars, as well as proteins ...
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... of molecules will be targeted to degradation and these molecules may be delivered to a different endocytic compartment containing different sets of proteases, such as granzymes. It is also possible that ligand binding may influence processing as discussed below. As a consequence of their differentia ...
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... • The direction of water movement in a cell depends on the concentration of the cell’s outside environment. • If the solution is hypertonic, or has a higher solute concentration than the cytoplasm does, water moves out of the cell. The cell loses water and shrinks. • If the solution is hypotonic, or ...
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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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