• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
371_section quiz
371_section quiz

... a. affects fewer genes than Y chromosome expression b. occurs in cells of female mammals c. disables some chromosomes in cells of male mammals d. determines phenotype in male mammals 3. A person who is heterozygous for a disorder caused by recessive alleles is a carrier ...
Full Text
Full Text

... shell. These cysts are viable for long periods and can be activated when environmental conditions are favorable. Once the cyst is activated, the embryo resumes development and gives rise in a few hours to a swimming nauplii that continues the development, through several molts, to the adult animal. ...
ion
ion

Human Genome and Human Genome Project
Human Genome and Human Genome Project

... is the particular side-by-side arrangement of bases along the DNA strand. This order spells out the exact instructions required to create a particular organism. • The genome is an organism’s complete set of DNA. Except for mature red blood cells, all human cells contains a complete genome arranged i ...
PDF of the article
PDF of the article

... that a number of projects and networks in the last few years were dedicated to the epigenome. A considerable amount of pioneering research has therefore already been carried out, particularly in Europe. More and more scientists recognized that it was time to launch a large-scale project to go about ...
Onl_Er_MSB_166890_supinfo0002 10..14
Onl_Er_MSB_166890_supinfo0002 10..14

... A Experimental design of stimulations in HAP1 cells. HAP1 cells were seeded in 12-well plates, cultured for 36 h in standard medium (10% FBS) and 16 h under reduced serum conditions (0.5% FBS). Following stimulation for 6 h, total RNA was isolated and libraries prepared for next-generation sequencin ...
DNA - pupul.ir pupuol
DNA - pupul.ir pupuol

... sequences or introns, is not clear. 24% of the total human genome • They may serve to separate functional domains (exons) of coding information in a form • that permits genetic rearrangement by recombination to occur more rapidly than if • all coding regions for a given genetic function were contigu ...
Intro to Genetics PowerPoint - E
Intro to Genetics PowerPoint - E

... While Mendel’s research only explains how some traits are inherited we can predict the probability of traits showing up in offspring ...
click here
click here

17.2_Evolution_as_Genetic_Change_in_Populations
17.2_Evolution_as_Genetic_Change_in_Populations

... Genetic Equilibrium ...
Using Molecular Markers in Plant Genetics
Using Molecular Markers in Plant Genetics

... development,” says Dr. Jim Register, research coordinator of analytical nucleic acid technologies at Pioneer. “SSR markers are considered highly polymorphic as the number of repeats can vary greatly among plants. This allows us to detect many different alleles for that marker. “These highly polymorp ...
Gene Section USP6 (ubiquitin specific protease 6 (Tre-2 oncogene))
Gene Section USP6 (ubiquitin specific protease 6 (Tre-2 oncogene))

Introduction
Introduction

... chance to survive. It is ironic to me that in order to survive tigers must rely on humans when humans are the reason they are endangered. I think the Genome Resource Bank seems to be an extremely good idea and should be further researched. Nature is very important in this world. It is estimated that ...
Aus dem  Max-Planck-Institut für Psychiatrie
Aus dem Max-Planck-Institut für Psychiatrie

... 1.1.1 Overview of Function All organisms strive towards maintaining their homeostasis, i.e. the dynamic equilibrium of their internal milieus that is essential for survival. The challenge of homeostasis by internal or external factors is classically referred to as “stress”. “Stress reaction” is the ...
No Slide Title
No Slide Title

... Telomerases are nucleoproteins whose function is to add DNAsequence repeats to the 3' end of the DNA strands in the telomeres at the ends of linear eukaryotic chromosomes. The de novo addition of TTAGGG repeats by the enzyme telomerase partially or wholly compensates for telomere shortening. Telomer ...
Warm-up - Foothill Technology High School
Warm-up - Foothill Technology High School

... A change in the genetic material (DNA or RNA) of a cell – Somatic: If it occurs in body cells, it can’t be passed on to next generation – Germ-line: If it occurs in gametes, it can be passed on to next generation Back to Mutations ...
PAG2006workshop
PAG2006workshop

... Maps: Search and view mapped genes, markers, QTL and clones using various types of maps (including genetic, physical and sequence); Compare maps; Examine genetic co-linearity between species. Markers: Find a marker based upon name, type or species; View it’s detail; Link to the maps, literature and ...
notes - local.brookings.k12.sd.us
notes - local.brookings.k12.sd.us

... expressed (made into RNA) at any given time. How does the cell decide which will be turned on and which will stay “silent”? You already know about _____________ regions that show RNA polymerase where to start. There are other ______________________ that control whether a gene is ON or OFF. ...
No Slide Title
No Slide Title

... Pachter, L. Ph.D. Thesis, MIT (1999) Human and Mouse Gene Structure: Comparative Analysis and Application to Exon Prediction. Batzoglou, S., Pachter, L., Mesirov, J., Berger, B., Lander, E. Genome Research (2000). ...
Beyond Mendel
Beyond Mendel

... A change in the genetic material (DNA or RNA) of a cell – Somatic: If it occurs in body cells, it can’t be passed on to next generation – Germ-line: If it occurs in gametes, it can be passed on to next generation Back to Mutations ...
PHYOGENY & THE Tree of life
PHYOGENY & THE Tree of life

... search for trees that are parsimonious & have a high probability ...
Carrots and Genomics
Carrots and Genomics

... • Mimics the process of DNA duplication in the plant • The polymerase (enzyme) requires dsDNA to start building in nucleotides ...
Genomic disorders: structural features of the genome can lead to
Genomic disorders: structural features of the genome can lead to

... myelin gene PMP22, which is separated from genes. A dosage-sensitive gene (open horizontal rectangle) or genes (n>1) located 0.5 Mb from the proximal is flanked by a repeat (black arrows) in tandem orientation. If recombination occurs or centromeric copy of CMT1A– between mis-aligned flanking repeat ...
DNA and Evolution
DNA and Evolution

... – Gene A in a new species probably has the same function as the similar gene B in another species because both species need to solve the same problem and they are related by evolutionary descent from a common ancestor. – We look at gene sequences and other features and make a decision that the diffe ...
PDF
PDF

... regions of the neural tube, and a loss of FatJ leads to an increase in the size of the progenitor pool in this region. This effect is mediated via the Hippo pathway component Yap1. Thus, this first report of a large-scale RNAi screen in a whole vertebrate organism reveals an important role for FatJ ...
< 1 ... 885 886 887 888 889 890 891 892 893 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report