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Assessment Specifications
Assessment Specifications

... Understanding of the structure of DNA, and the meaning of semi-conservative replication as part of cell division, is expected. Factors affecting the processes may include both direct and indirect availability of resources. Factors that affect enzyme activity within cells may include temperature, pH, ...
Reproductive cloning
Reproductive cloning

... alongside GM crop to slow the selection pressure for resistance – gene flow: modified genes may spread to non-GM species due to interbreeding ...
DNA, Genes & Genomes
DNA, Genes & Genomes

... All life forms rely on nucleic acids (DNA & RNA) for passing on their genetic information. DNA is a complex polymer of repeating nucleotides Each nucleotide = Deoxyribose Sugar + Phosphate + Nitrogenous Base. ...
Supplementary Material (doc 44K)
Supplementary Material (doc 44K)

... For MCF7-LMO4-TetOff cells, we used the HG-U133A and B arrays, and for the MCF7-DNClim-TetOff cells we used the HG-U133 Plus 2.0 arrays. The two types of arrays are directly comparable because all probe sets within the HG-U133A and B arrays (44692 probe sets) are represented in the HG-U133 Plus 2.0 ...
Reading: DNA the Ultimate Identifier
Reading: DNA the Ultimate Identifier

... ...
Genetic Technology
Genetic Technology

... PCR. It stands for polymerase chain reaction. Scientists automated the process. They could then ...
投影片 1
投影片 1

... A new powerful technology for biological exploration ...
Genetic Engineering
Genetic Engineering

... The simple addition, deletion, or manipulation of a single trait in an organism to create a desired change. ...
No Slide Title
No Slide Title

... Gene of interest can not have restriction site within its sequence FIGURE 20.9 ...
Biology Chapter 11-1
Biology Chapter 11-1

... Ex. German Sheppard’s, toy poodles, and Great Danes Hybridization- A cross between dissimilar individuals. (usually between different, but related, species.) Ex. Mules and pigs Mutagens- substances in the environment, such as radiation and chemicals, that cause mutations. Genetic engineering- a form ...
MCAS BIOLOGY REVIEW GENETICS AND EVOLUTION
MCAS BIOLOGY REVIEW GENETICS AND EVOLUTION

... from DNA Translation takes place at the ribosome in the cytoplasm; translates mRNA to tRNA to amino acid ...
Genetics 2. A typical cell of any organism contains genetic
Genetics 2. A typical cell of any organism contains genetic

... As a basis for understanding this concept, students know: a. the differences between the life cycles and reproduction of sexual and asexual organisms. b. sexual reproduction produces offspring that inherit half their genes from each parent. c. an inherited trait can be determined by one or ...
Chapter 21 The Genetic Control of Animal Development
Chapter 21 The Genetic Control of Animal Development

... During B cell development, the kappa light chain gene that will be expressed is assembled from one LV segment, one J segment, and the C segment by somatic recombination.  Segment joining is mediated by recombination signal sequences adjacent to each gene segment by a protein complex including ...
Determinants of Gene Duplicability
Determinants of Gene Duplicability

... eyeless in fruitflies • The two proteins have highly similar paired domains. • Mouse Pax 6 gene can induce eye development in Drosophila, despite more than 600 million years of separation! Despite great differences in eye type, Drosophila and human use Pax 6 to control eye development! ...
Two Epigenetic Mechanisms
Two Epigenetic Mechanisms

... Refers to changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence. Enables a cell/organism to respond to its dynamic external environment during development and throughout life! Epigenetic changes to the genome can be inherited if these changes occur in cell ...
Genetics I
Genetics I

... 9. Section of a chromosome __gene___________________________________ 10. Gene that keeps other genes from showing trait ___dominant_____________ 11. Recessive gene __genes that do not show traits in presence of dominant gene 12. Heterozygous _has a dominant and recessive gene for a trait_____ 13. Me ...
Mendel chp 5 notes
Mendel chp 5 notes

... iii. variably expressive – intensity varies in different people 1. some people may have an extra digit on every extremity or some may just have a partial digit on one extremity h. Pleiotropy - one gene (protein) controls several functions or has more than one effect i. Phenocopy – an environmentally ...
PAN Shen Quan
PAN Shen Quan

... • Molecular basis for bacterial pathogenesis • Protein engineering • DNA and protein delivery systems • Vectors for gene therapy and DNA vaccines As a natural genetic engineer of plants, Agrobacterium tumefaciens can deliver T-DNA into different eukaryotes, including plant, yeast, fungal and human c ...
Find the Disease Genes
Find the Disease Genes

... 1) In vitro analyses: OK but associated with artefacts 2) In vivo would be the ideal: can we generate animals that are either over-expressing the gene or that have it switched off? ...
Gene Section LCP1 (lymphocyte cytosolic protein1) Atlas of Genetics and Cytogenetics
Gene Section LCP1 (lymphocyte cytosolic protein1) Atlas of Genetics and Cytogenetics

Senescence
Senescence

... A few species, like this gecko, are parthenogenic. This means that all individuals are female, and their offspring are exact genetic copies of themselves, or clones. ...
WHO and patenting of genes
WHO and patenting of genes

... Intellectual property, sharing benefits of research present situation is little less than chaotic…. Invention, natural occurrence: ...
Characteristics of Living Things
Characteristics of Living Things

... stimulus is a signal to which an organism ...
Document
Document

... DGNGMNAWVA WRNRCKGTDV QAWIRGCRL ...
Genomics
Genomics

... related (and unrelated) species EG: man and chimp This requires sequencing of many genomes. ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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