• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
DNA Manipulation
DNA Manipulation

... The Human Genome Project has the goals of 1) mapping and sequencing all of the DNA basepairs 2) identify ALL genes within the sequence. ...
1 - Genetic Alliance
1 - Genetic Alliance

... The human genome (total composition of genetic material within a cell) is packaged into larger units known as chromosomes—physically separate molecules that range in length from about 50 million to 250 million base pairs. Human cells contain two sets of chromosomes, one set inherited from each paren ...
Prokaryotic genome-size evolution Range of C values in prokaryotes
Prokaryotic genome-size evolution Range of C values in prokaryotes

... Cline, O. White, C.M. Fraser, H.O. Smith, J.C. Venter . 1999. Global transposon mutagenesis and a minimal Mycoplasma genome. Science ...
Biology Final Study Guide
Biology Final Study Guide

... homozygous, incomplete dominance, phenotype 19. What are chromosomes? a. How many chromosomes do humans have? b. How many are passed on to offspring? 20. What occurs during the stages of mitosis & meiosis? 21. Compare & contrast mitosis and meiosis (# of cells made, type of cells, # of chromosomes)? ...
Ghost in Your Genes Response
Ghost in Your Genes Response

... 1. What was the expectation of the Human Genome Project? ...
Methods Used in Medical and Population Genetics
Methods Used in Medical and Population Genetics

... expression microarrays to measure genome-wide ...
Chapter 21 The Genetic Control of Animal Development
Chapter 21 The Genetic Control of Animal Development

...  The Drosophila homeotic genes form two large clusters on one of the autosomes.  All of the homeotic genes encode helix-turn-helix transcription factors with a conserved homeodomain region involved in DNA binding. These genes control a regulatory cascade of target genes that control segment identi ...
Bioinformatics Tools and Genomes to Life
Bioinformatics Tools and Genomes to Life

... matrix of interactions. • Matrix was 436 metabolites by 720 enzyme catalyzed reactions. • Found best model with flux balance analysis of matrix and an optimizing algorithm, very computationally intensive. • Compared predictions of deleted intermediaries to experimental observations. ...
Name:
Name:

... o Electrophoresis: How does it work? What can it be used for?  How is the data used to identify criminals?  How are DNA fragments produced?  How does the electrophoresis chamber separate the DNA fragments?  Why do individuals have unique DNA fingerprints?  How can you tell fragment size?  Regu ...
Mutations
Mutations

... ...
Gene Therapy
Gene Therapy

... Why do DNA fragments move towards the positive end of the gel? How are the fragments separated? (by what trait) What is the end result? What are some uses of electrophoresis? ...
Gene Section HOXA11 (homeobox A11) Atlas of Genetics and Cytogenetics
Gene Section HOXA11 (homeobox A11) Atlas of Genetics and Cytogenetics

In search of the Cholesterol Gene
In search of the Cholesterol Gene

... ...
document
document

... Privat genetic life (Baudouin, 1994) ...
dihybrid cross: a genetic cross which examines the transmission of
dihybrid cross: a genetic cross which examines the transmission of

... genetic screening: tests to identify the presence or absence of changed or harmful genes possessed by an individual. genotype: genetic makeup of an individual or the genes that they inherit, e.g. Tt. heredity: the natural law or property of organisms whereby their offspring have various physical and ...
Creating mosaics in Drosophila
Creating mosaics in Drosophila

... example, expression of a specific gene can be driven in a tissue specific manner under the control of specific transcriptional regulatory sequences, or uniformly under the control of an heat shock promoter. These techniques, however, are limited by the availability of cloned and characterized promot ...
Genetics of MD - Myotonic Dystrophy Foundation
Genetics of MD - Myotonic Dystrophy Foundation

... chromosome consists of a long chain of chemicals that form the units of DNA. These units are called nucleotide bases. The disease is characterized by stretches of DNA (abbreviated CTG) on the DMPK (dystrophia-myotonic protein kinase) gene that are repeated several times. It is sometimes referred to ...
Suppressors
Suppressors

... The motivation for most suppressors screens is to find more genes that affect the same biological process as the original gene. Two types of suppression: I. Suppression – a mutation in one gene alleviates the defect of a mutation in another gene—“low-copy” suppressor. II. Suppression – overexpressio ...
DNA Structure and Replication
DNA Structure and Replication

... • DNA molecule separates at its bases • Forms split, or replication fork • Each strand acts as a template ...
Biology 303 EXAM III
Biology 303 EXAM III

... Regarding the sequencing of genomes, which statement is true? 1. most of the human genome has been sequenced. 2. no eukaryotic genome has yet been sequenced. 3. DNA sequencing has revealed a complete lack of polycistronic transcription units in eukaryotic genomes. 4. eukaryotic genomes display a hig ...
Genomic analysis of metastasis reveals an essential role for RhoC
Genomic analysis of metastasis reveals an essential role for RhoC

... Analysis: Hierarcial clustering ...
Quick Vocabulary Lesson 1 Lesson 2 dominant trait
Quick Vocabulary Lesson 1 Lesson 2 dominant trait

Haploid (__)
Haploid (__)

... Errors in the genes occur 1 for every ____________ nucleotides read Causes of ERRORS ...
Chapter 10.2
Chapter 10.2

... _________: sequence of DNA that can be bound by a _____________ ___________  Located __________ of nucleotide bases away from __________  Loop in DNA may bring ________ and its attached transcription factor (________) into _______ with the transcription factors and RNA polymerase at the ...
File - Year 11 Revision
File - Year 11 Revision

... Give one feature of a bacterial cell that isn’t present in animal or plant cells. What is the function of the mitochondria? By how much can a light microscopes magnify a specimen? What do the letters A, T, C and G stand for in DNA? A specimen appears 15mm under a light microscope at a magnification ...
< 1 ... 1188 1189 1190 1191 1192 1193 1194 1195 1196 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report