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Microbiology Unit 3 Study Guide
Microbiology Unit 3 Study Guide

... to transport genetic material into a target organism? 13. What are the two most commonly used vectors for getting DNA into organisms? 14. How does replication of a bacterial chromosome occur? 15. How is the leading strand in DNA replication different from the lagging strand? ...
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... staining with coomassie blue • This is a dye that binds all proteins regardless of their amino acid makeup • Fortunately it is bright blue – no UV ...
Introduction to Genetics and Genomics
Introduction to Genetics and Genomics

... • 10% of the genes have been suggested to encode more than 90% of the proteins • Protein complexity -- comes from: – 40% of human/mouse genes are alternatively spliced – multiple transcription start sites – polyadenlylation and pre-mRNA editing – posttranslational protein modification ...
Slide 1
Slide 1

... ______________that make it more likely for an ______________ to survive and successfully ______________ become more common in a ______________ over successive generations. It is a key mechanism of ______________. ...
Exploring Mutant Organisms Teacher Extended Background
Exploring Mutant Organisms Teacher Extended Background

... How do mutations occur? Spontaneous mutations occur during DNA replication in the process of mitosis (cell division). There are enzymes in the cell that proof-read newly replicated DNA, but if they miss a change, this change gets incorporated into the DNA and will be maintained when the DNA is repli ...
5.2 Human Genetic Disorders File
5.2 Human Genetic Disorders File

... POINT > Distinguish between gene and chromosomal mutations POINT > Describe examples of genetic diseases caused by single gene mutations POINT > Identify human diseases caused by chromosomal mutations POINT > Explain Pedigree analysis ...
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This examination paper consists of 4 pages

... Can hold large pieces of chromosomal DNA Are rodent cell lines Are produced by irradiation with UV light Have been used in mapping the yeast genome ...
Participation to Symposia (last 10 years) :
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... First Doctoral Thesis in Molecular Biology, University of Paris Doctoral Thesis in Molecular Biology, University of Paris ...
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9.1 - How Do Populations Evolve SG

... Mutation: a change that occurs in the DNA of an individual. Gene flow: the net movement of alleles from one population to another due to the migration of individuals. Non-random mating: mating among individuals on the basis of mate selection for a particular phenotype or due to breeding. Genetic dri ...
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Prepractical demo_SF_Class_2009

... - different ones detect different chemicals - all transmit same signal: “bitter”   Species-specificity - repertoire of receptors adapted for chemicals that must be detected e.g. cats lack functional sweet receptor and do not prefer sweet-tasting foods   Genetic variation within species - mutations ...
in situ - Moodle NTOU
in situ - Moodle NTOU

... – We are going to integrate the tools and idea you learned from this course, and apply them to finish a project. – In this project, you have to choose a human gene which you are interested. Then try to search the related genes from mouse and zebrafish. Try to dig out the resources from other animal ...
Passarge, E. Taschenatlas der Genetik
Passarge, E. Taschenatlas der Genetik

... year of a publication of Andreas Vesalius De humani corporis fabrica libri septi, and concluding with 2003 – the year of complete sequence of the human genome. The volume is composed of 4 parts arranged in non-numbered chapters. This publication takes into account the arrangement for genetics and hu ...
Studying the Embryo Lethality of AT5G03220
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... Is this T-DNA Insertion Embryo Lethal? ...
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lecture12

... copy of the parent locus -gain a new function through mutation & selection -become functionless pseudogenes ...
Chapter 9 answers
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... What would happen if all the genes in a cell were always active? It would take a huge amount of materials and energy in order to make all the proteins. Most of them would not be needed, and would take up space in the cell, or else they would need to be broken down again so the raw materials could be ...
Pre/Post Test
Pre/Post Test

... Why can bacteria recognize a human gene and then produce a human protein? A. DNA replication in bacteria and humans is the same. B. Bacterial cells contain the same organelles as human cells. C. The basic components of DNA are the same in humans and bacteria. D. Bacterial cells and human cells conta ...
Genetic Disorders and Hereditary Diseases
Genetic Disorders and Hereditary Diseases

... An error during meiosis causes a sperm cell or an egg cell to have some defect. If one of these gametes is involved in fertilization, it usually results in miscarriage, but in a few cases, a baby will develop and be carried to term with a genetic disorder EX. Down Syndrome is caused by an extra 21st ...
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Conjugation Answer Sheet
Conjugation Answer Sheet

... Conjugation – Answer Sheet Occasionally two bacteria can exchange DNA by structure called the ...
Biology Final Study Guide
Biology Final Study Guide

... homozygous, incomplete dominance, phenotype 19. What are chromosomes? a. How many chromosomes do humans have? b. How many are passed on to offspring? 20. What occurs during the stages of mitosis & meiosis? 21. Compare & contrast mitosis and meiosis (# of cells made, type of cells, # of chromosomes)? ...
No Slide Title
No Slide Title

... Cystic Fibrosis as Candidate for Gene Therapy 1. Recessive gene on chromosome 7. 2. CFTR is the gene product. 3. CFTR is an ion channel protein. 4. Normal gene sequence has been cloned. 5. Symptoms are localized to specific organs. 6. Adenovirus (cold virus) can be used to deliver normal sequence t ...
Integrated Science 3/4 Course Map Biology_EOC_FAQ_2016
Integrated Science 3/4 Course Map Biology_EOC_FAQ_2016

... imbalance here can disrupt the equilibrium and bad things result! 6. Why do some populations get along when others don’t? At some level, all populations compete with each other since resources (what they are after) are limited. However, it is not uncommon to see cooperation among two or more organis ...
DNA Structure and Function
DNA Structure and Function

... - Antibodies to fight disease ...
mutation PP
mutation PP

... • Any change to a DNA sequence is a mutation. • Therefore, a MUTANT is an organism with a DNA sequence that has changed… meaning all of us! • Very few mutations are advantageous, some are harmful, but most make no difference at all (silent mutations), since about 90-95% of your DNA does not code for ...
DNA Manipulation
DNA Manipulation

... The Human Genome Project has the goals of 1) mapping and sequencing all of the DNA basepairs 2) identify ALL genes within the sequence. ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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