Genome of Drosophila species
... The large diversity of transcription factors is likely related to the substantial regulatory complexity of the fly Many of the genes involved in core processes are single-copy genes and thus provide starting points for detailed studies of phenotype, free of the complications of ...
... The large diversity of transcription factors is likely related to the substantial regulatory complexity of the fly Many of the genes involved in core processes are single-copy genes and thus provide starting points for detailed studies of phenotype, free of the complications of ...
Lecture series on “The Human Genome”
... With the completion of the mouse genome sequence, a key goal for functional genomics is the creation of a series of mutant alleles for every mammalian gene. The most versatile organism to study mammalian gene function is the mouse as there is an extensive toolkit for modifying the genome and specifi ...
... With the completion of the mouse genome sequence, a key goal for functional genomics is the creation of a series of mutant alleles for every mammalian gene. The most versatile organism to study mammalian gene function is the mouse as there is an extensive toolkit for modifying the genome and specifi ...
Fish sampling - BioMed Central
... The fish were killed by a blow to the head. Tissue samples from six organs, i.e. gills, liver, head kidney, brain, white muscle and posterior intestine, were dissected out and immediately frozen in cryo tubes in liquefied nitrogen and stored at –80°C before further processing. After weight and lengt ...
... The fish were killed by a blow to the head. Tissue samples from six organs, i.e. gills, liver, head kidney, brain, white muscle and posterior intestine, were dissected out and immediately frozen in cryo tubes in liquefied nitrogen and stored at –80°C before further processing. After weight and lengt ...
No Slide Title
... Out of Africa • Neanderthal mT DNA: – Very different from modern humans – Hard to reconcile difference with possible presence of some Neanderthal ancestry in modern ...
... Out of Africa • Neanderthal mT DNA: – Very different from modern humans – Hard to reconcile difference with possible presence of some Neanderthal ancestry in modern ...
Presentation
... Amniocentesis - a small amount of amniotic fluid (containing fetal tissues and cells) is extracted from the amniotic sac surrounding the developing fetus - the DNA is examined for genetic abnormalities Chorionic Villi Sampling (CVS) - the removal of a small piece of the placenta (chorionic villi) d ...
... Amniocentesis - a small amount of amniotic fluid (containing fetal tissues and cells) is extracted from the amniotic sac surrounding the developing fetus - the DNA is examined for genetic abnormalities Chorionic Villi Sampling (CVS) - the removal of a small piece of the placenta (chorionic villi) d ...
Chapter 13
... – a selectable marker (antibiotic resistance gene) – a cloning site (site where insertion of foreign DNA will not disrupt replication or inactivate essential markers ...
... – a selectable marker (antibiotic resistance gene) – a cloning site (site where insertion of foreign DNA will not disrupt replication or inactivate essential markers ...
BCPS Biology Reteaching Guide Genetics Vocab Card Definitions
... tightly coiled DNA within the nucleus containing the genetic information that is passed from one generation of cells to the next. Humans have 46 chromosomes; 23 pairs ...
... tightly coiled DNA within the nucleus containing the genetic information that is passed from one generation of cells to the next. Humans have 46 chromosomes; 23 pairs ...
Control & Regulation
... about by the fact that certain genes switch on and other switch off. In other types of cell, it is different genes which are switched on, e.g. in plants, the genes which produce chlorophyll must be switched on in leaf cells but switched off in root cells. 23 May 2017 ...
... about by the fact that certain genes switch on and other switch off. In other types of cell, it is different genes which are switched on, e.g. in plants, the genes which produce chlorophyll must be switched on in leaf cells but switched off in root cells. 23 May 2017 ...
Genomics
... change in mutant relative to wild-type Coupling Microarrays and Yeast Genetics: Mutant v. Wild-type Cell type 1 = WT Cell type 2 = Mutant ...
... change in mutant relative to wild-type Coupling Microarrays and Yeast Genetics: Mutant v. Wild-type Cell type 1 = WT Cell type 2 = Mutant ...
3. The Gene Pool - NCEA Level 2 Biology
... • How many of each individual allele exist? • B = 8 x 2 + 6 =22 b = 6 x 2 +6 = 18 • f(B) = 22/40 = 0.55 f(b)= 18/40 = 0.45 ...
... • How many of each individual allele exist? • B = 8 x 2 + 6 =22 b = 6 x 2 +6 = 18 • f(B) = 22/40 = 0.55 f(b)= 18/40 = 0.45 ...
lz(g)
... Two different recessive mutants, both with the same phenotype (small eyes and fused facets). Are they mutations in the same gene? Make two different fly lines and compare their phenotypes. ...
... Two different recessive mutants, both with the same phenotype (small eyes and fused facets). Are they mutations in the same gene? Make two different fly lines and compare their phenotypes. ...
Nutrigenomics? Epigenetics? The must-know
... would have assumed that we would be powerless to stop it developing in ourselves as well. What’s been unfolding over the last decade is the exciting fact that we DO have significant control over our genome in ways we never thought possible. And this can translate to much better health for us all. ...
... would have assumed that we would be powerless to stop it developing in ourselves as well. What’s been unfolding over the last decade is the exciting fact that we DO have significant control over our genome in ways we never thought possible. And this can translate to much better health for us all. ...
PowerPoint
... Compare each line of the one that you know to the lines in the same position on each of the possible matching fingerprints. If there is one line that does not match in location or size, that one is eliminated from the process. A match must have all lines in the same position and of the same si ...
... Compare each line of the one that you know to the lines in the same position on each of the possible matching fingerprints. If there is one line that does not match in location or size, that one is eliminated from the process. A match must have all lines in the same position and of the same si ...
PowerPoint-Präsentation
... Of all CpG sites annotated to these identified genes, only about 10% were concordant with expression. These CpG site were within or immediately upstream of the annotated start of the gene with a maximum distance of ≈1500 nucleotides, indicating that overlap with the promoter site is most likely. A c ...
... Of all CpG sites annotated to these identified genes, only about 10% were concordant with expression. These CpG site were within or immediately upstream of the annotated start of the gene with a maximum distance of ≈1500 nucleotides, indicating that overlap with the promoter site is most likely. A c ...
Gene Targeting
... • If YFG* has no easily measurable phenotype associated with it, we can tag it with a marker that we can detect • In our example, we will tag YFG* with a URA3 and transform it into a yeast strain that can’t produce uracil • If we linearize a plasmid that has URA3 and YFG*, the end sequences will rec ...
... • If YFG* has no easily measurable phenotype associated with it, we can tag it with a marker that we can detect • In our example, we will tag YFG* with a URA3 and transform it into a yeast strain that can’t produce uracil • If we linearize a plasmid that has URA3 and YFG*, the end sequences will rec ...
outline File - selu moodle
... Males and females express the same levels of certain genes found on the X chromosome Dosage compensation In females one X chromosome is randomly selected for modification 13.3 Exceptions to the Chromosomal Theory of Inheritance Mitochondrial and chloroplast DNA is inherited only from the egg cell. 1 ...
... Males and females express the same levels of certain genes found on the X chromosome Dosage compensation In females one X chromosome is randomly selected for modification 13.3 Exceptions to the Chromosomal Theory of Inheritance Mitochondrial and chloroplast DNA is inherited only from the egg cell. 1 ...
BLOOD GROUP GENOTYPING: THE FUTURE IS NOW
... named after the bacteria in which they are found – Hind III, Eco RI ...
... named after the bacteria in which they are found – Hind III, Eco RI ...
Biology 303 EXAM II 3/14/00 NAME
... did her father. Which of her parents underwent nondisjunction during meiosis, giving rise to the gamete responsible for the syndrome? ...
... did her father. Which of her parents underwent nondisjunction during meiosis, giving rise to the gamete responsible for the syndrome? ...
Chapter 16-17 review sheet
... 5. Explain why the ends of chromosomes get shorter with each replication. 6. Describe the role of telomeres in DNA. Why do we need these repeats on the ends of our chromosomes? Why must cancer activate its telomerase genes? In what other cell type(s) do we find telomerase? 7. Make sure you can trans ...
... 5. Explain why the ends of chromosomes get shorter with each replication. 6. Describe the role of telomeres in DNA. Why do we need these repeats on the ends of our chromosomes? Why must cancer activate its telomerase genes? In what other cell type(s) do we find telomerase? 7. Make sure you can trans ...
What are transgenic bacteria? Illustrate using any one example. 2
... the deletion of the gene for adenosine deaminase. In some children ADA deficiency can be cured by bone marrow transplantation; in others it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But the problem with both of these approaches is tha ...
... the deletion of the gene for adenosine deaminase. In some children ADA deficiency can be cured by bone marrow transplantation; in others it can be treated by enzyme replacement therapy, in which functional ADA is given to the patient by injection. But the problem with both of these approaches is tha ...
Mutation
... Only mutations in the sex cells (male sperm or female eggs) will be passed on to the offspring (child). A mutation in a stomach cell or liver cell will not be passed on to the child. Mutations can be caused by: cells being exposed to too much radiation, (such as x rays or ultraviolet rays from the ...
... Only mutations in the sex cells (male sperm or female eggs) will be passed on to the offspring (child). A mutation in a stomach cell or liver cell will not be passed on to the child. Mutations can be caused by: cells being exposed to too much radiation, (such as x rays or ultraviolet rays from the ...
Genetics Unit 4 – Genetic Technology
... 2. Add a specific __________________ that splices out only _________ gene. 3. Isolate ___________________ from bacterium. 4. Add same restriction enzyme to plasmid DNA that was used with the donor DNA. This enzyme can only __________________________ to open it up. 5. _________________ the two DNA sa ...
... 2. Add a specific __________________ that splices out only _________ gene. 3. Isolate ___________________ from bacterium. 4. Add same restriction enzyme to plasmid DNA that was used with the donor DNA. This enzyme can only __________________________ to open it up. 5. _________________ the two DNA sa ...
Answers to Mastering Concepts Questions
... 1. Mendel chose pea plants because they are easy to grow, develop quickly, produce many offspring, and have many traits that appear in two alternate forms that are easy to distinguish. It also is easy to hand-pollinate pea plants, so an investigator can control which plants mate with one another. 2. ...
... 1. Mendel chose pea plants because they are easy to grow, develop quickly, produce many offspring, and have many traits that appear in two alternate forms that are easy to distinguish. It also is easy to hand-pollinate pea plants, so an investigator can control which plants mate with one another. 2. ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse