COMPLETE PRESCRIBING INFORMATION
... The overall benefits and possible risks of hormone replacement therapy should be fully considered and discussed with patients. It is important that the modest increased risk of being diagnosed with breast cancer after 4 years of treatment with combined estrogen plus progestin HRT (as reported in the ...
... The overall benefits and possible risks of hormone replacement therapy should be fully considered and discussed with patients. It is important that the modest increased risk of being diagnosed with breast cancer after 4 years of treatment with combined estrogen plus progestin HRT (as reported in the ...
alprolix - Biogen Canada
... ALPROLIX can affect fertility or sperm development in hemophilia B patients. No impact on male or female reproductive organs was shown in toxicology studies in rats and monkeys. Special Populations Pregnant Women: ALPROLIX should be used during pregnancy only if the potential benefit justifies the p ...
... ALPROLIX can affect fertility or sperm development in hemophilia B patients. No impact on male or female reproductive organs was shown in toxicology studies in rats and monkeys. Special Populations Pregnant Women: ALPROLIX should be used during pregnancy only if the potential benefit justifies the p ...
Dose-response and pharmacokinetic study with ... bismesylate after single oral administrations ...
... ABSTRACT: To better define the dose-effect relationship and the pharmacokinetics or almitrine, sixteen stable hypoxaemic COPD patients received random single oral administrations or almltrlne blsmesylate 50, 100 and 150 mg or placebo at two-week Intervals In a double-blind manner. Resting ventilatio ...
... ABSTRACT: To better define the dose-effect relationship and the pharmacokinetics or almitrine, sixteen stable hypoxaemic COPD patients received random single oral administrations or almltrlne blsmesylate 50, 100 and 150 mg or placebo at two-week Intervals In a double-blind manner. Resting ventilatio ...
Dosage and route of administration The recommended
... ACTONEL has an affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, ACTONEL inhibits osteoclasts. The osteoclasts adhere normally to the bone surface, but show evidence of reduced active resorption (e.g., lack of ruffled border). Histomorphometry i ...
... ACTONEL has an affinity for hydroxyapatite crystals in bone and acts as an antiresorptive agent. At the cellular level, ACTONEL inhibits osteoclasts. The osteoclasts adhere normally to the bone surface, but show evidence of reduced active resorption (e.g., lack of ruffled border). Histomorphometry i ...
cdph/oa/adap - Magellan Rx
... Refills may be obtained after 80 percent of the previously dispensed days’ supply has been used; however, there is an annual maximum of 13 fills per prescription. ...
... Refills may be obtained after 80 percent of the previously dispensed days’ supply has been used; however, there is an annual maximum of 13 fills per prescription. ...
Product Monograph
... withdrawal or lowering of the dose of MAVIK®, has been reported. Such possibility should be considered as part of the differential diagnosis of cough. Endocrine and Metabolism Hyperkalemia and Potassium-Sparing Diuretics Elevated serum potassium has been observed in hypertensive patients, especially ...
... withdrawal or lowering of the dose of MAVIK®, has been reported. Such possibility should be considered as part of the differential diagnosis of cough. Endocrine and Metabolism Hyperkalemia and Potassium-Sparing Diuretics Elevated serum potassium has been observed in hypertensive patients, especially ...
Full Prescribing Information
... Serious adverse cardiac events, including acute myocardial infarction, have been reported within a few hours following administration of AXERT® (almotriptan malate). Life-threatening disturbances of cardiac rhythm and death have been reported within a few hours following the administration of other ...
... Serious adverse cardiac events, including acute myocardial infarction, have been reported within a few hours following administration of AXERT® (almotriptan malate). Life-threatening disturbances of cardiac rhythm and death have been reported within a few hours following the administration of other ...
roxithromycin - ResearchGate
... B. DOSING INFORMATION: Adults: Usual oral doses are 150 mg twice a day or 300 mg once daily for 10 days. Children: Usual doses are 2.5 to 5 mg/kg every 12 hours for 10 days. C. PHARMACOKINETICS: Roxithromycin is rapidly absorbed; peak serum levels occur 2 hours after administration. Penetrates w ...
... B. DOSING INFORMATION: Adults: Usual oral doses are 150 mg twice a day or 300 mg once daily for 10 days. Children: Usual doses are 2.5 to 5 mg/kg every 12 hours for 10 days. C. PHARMACOKINETICS: Roxithromycin is rapidly absorbed; peak serum levels occur 2 hours after administration. Penetrates w ...
File
... o Source: Prepared from bovine collagen. o Use: when applied to bleeding surface ,attracts platelets to form plug followed by natural clot. o Used in capillary bleeding. o It is non allergic but can promote local infection and abscess formation. o It is inactivated by autoclaving and hence should no ...
... o Source: Prepared from bovine collagen. o Use: when applied to bleeding surface ,attracts platelets to form plug followed by natural clot. o Used in capillary bleeding. o It is non allergic but can promote local infection and abscess formation. o It is inactivated by autoclaving and hence should no ...
azaCITIDine - Cancer Care Ontario
... The information set out in the drug monographs, regimen monographs, appendices and symptom management information (for health professionals) contained in the Drug Formulary (the "Formulary") is intended for healthcare providers and is to be used for informational purposes only. The information is no ...
... The information set out in the drug monographs, regimen monographs, appendices and symptom management information (for health professionals) contained in the Drug Formulary (the "Formulary") is intended for healthcare providers and is to be used for informational purposes only. The information is no ...
cloNIDine - DavisPlus
... ● ADHD: Assess attention span, impulse control, and interactions with others. ● Lab Test Considerations: May cause transientqin blood glucose levels. ● May causepurinary catecholamine and vanillylmandelic acid (VMA) concentra- ...
... ● ADHD: Assess attention span, impulse control, and interactions with others. ● Lab Test Considerations: May cause transientqin blood glucose levels. ● May causepurinary catecholamine and vanillylmandelic acid (VMA) concentra- ...
Product Monograph - Takeda Canada Inc.
... suppression if any child’s or adolescent’s growth appears slowed. In a one-year study, Alvesco® was shown to have no effect on growth rates compared to placebo when administered to pediatric patients at doses of up to 200 micrograms per day (see CLINICAL TRIALS). Osteoporosis and bone fracture are c ...
... suppression if any child’s or adolescent’s growth appears slowed. In a one-year study, Alvesco® was shown to have no effect on growth rates compared to placebo when administered to pediatric patients at doses of up to 200 micrograms per day (see CLINICAL TRIALS). Osteoporosis and bone fracture are c ...
A Practical Guide to Dermatological Drug Use in Pregnancy
... Tetracyclines (category D) are associated with deciduous tooth staining when taken after the first trimester, decreased bony growth, and maternal liver toxicity. However, inadvertent exposure in the first few weeks of pregnancy is extremely unlikely to be harmful.6 Erythromycin (category B) has long ...
... Tetracyclines (category D) are associated with deciduous tooth staining when taken after the first trimester, decreased bony growth, and maternal liver toxicity. However, inadvertent exposure in the first few weeks of pregnancy is extremely unlikely to be harmful.6 Erythromycin (category B) has long ...
SALIX PHARMACEUTICALS LTD (Form: 8-K
... three once-daily oral methylnaltrexone dosing regimens (150, 300 and 450mg), demonstrated highly statistically significant results for the primary endpoint in two of the three treatment arms when compared to the placebo treatment arm. Both the 300 and 450 mg treatment arms demonstrated highly statis ...
... three once-daily oral methylnaltrexone dosing regimens (150, 300 and 450mg), demonstrated highly statistically significant results for the primary endpoint in two of the three treatment arms when compared to the placebo treatment arm. Both the 300 and 450 mg treatment arms demonstrated highly statis ...
Overdose in the Emergency Department
... Multidose activated charcoal Multi-dose activated charcoal ...
... Multidose activated charcoal Multi-dose activated charcoal ...
¹ Analytical-Diagnostic Laboratory and Immuno-allergology
... or physician, we evaluate the first months of treatment to be highly positive. There are several advantages of SCIG over IVIG. The patient is satisfied with the current treatment, as an advantage she considers reducing the number of doctor’s office visits, less frequent contact with the patients in hea ...
... or physician, we evaluate the first months of treatment to be highly positive. There are several advantages of SCIG over IVIG. The patient is satisfied with the current treatment, as an advantage she considers reducing the number of doctor’s office visits, less frequent contact with the patients in hea ...
RIVOTRIL Product Monograph
... Patients with a history of depression and/or suicide attempts should be kept under close supervision. All patients treated with antiepileptic drugs (AEDs), irrespective of indication, should be monitored for signs of suicidal ideation and behaviour and appropriate treatment should be considered. Pat ...
... Patients with a history of depression and/or suicide attempts should be kept under close supervision. All patients treated with antiepileptic drugs (AEDs), irrespective of indication, should be monitored for signs of suicidal ideation and behaviour and appropriate treatment should be considered. Pat ...
Opioids Switching using Equivalence Tables
... Medication profile – dose may need to be adjusted to prevent adverse effects due to drug interaction7 5. The initial dose can then titrated as necessary to maintain pain control. An immediate release opioid should also be indicated for incident or breakthrough pain, especially during the titration ...
... Medication profile – dose may need to be adjusted to prevent adverse effects due to drug interaction7 5. The initial dose can then titrated as necessary to maintain pain control. An immediate release opioid should also be indicated for incident or breakthrough pain, especially during the titration ...
Bulletin #88
... For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (Amerge-GSK) For treatment of migraine headaches where other standard therapy such as an analgesic has failed. Eligibility will be restricted to beneficiaries ...
... For treatment of migraines where standard therapy such as an analgesic has failed or cannot be tolerated. naratriptan HCl, tablet, 1mg, 2.5mg (Amerge-GSK) For treatment of migraine headaches where other standard therapy such as an analgesic has failed. Eligibility will be restricted to beneficiaries ...
NEW ZEALAND DATA SHEET VOLTAREN® Description
... Lithium: If used concomitantly, diclofenac may raise plasma concentrations of lithium. Monitoring of the serum lithium level is recommended. Digoxin: If used concomitantly, diclofenac may raise plasma concentrations of digoxin. Monitoring of the serum digoxin level is recommended. Diuretics and ant ...
... Lithium: If used concomitantly, diclofenac may raise plasma concentrations of lithium. Monitoring of the serum lithium level is recommended. Digoxin: If used concomitantly, diclofenac may raise plasma concentrations of digoxin. Monitoring of the serum digoxin level is recommended. Diuretics and ant ...
Medical management of fibroids.
... The ideal medical therapy for fibroids is, arguably, a tablet that is taken by mouth, once a day or, even better, once a week, with minimal, if any, side-effects, that induces fibroid regression and thus a resolution of symptoms rapidly, but without affecting fertility. Such a magic bullet does not ...
... The ideal medical therapy for fibroids is, arguably, a tablet that is taken by mouth, once a day or, even better, once a week, with minimal, if any, side-effects, that induces fibroid regression and thus a resolution of symptoms rapidly, but without affecting fertility. Such a magic bullet does not ...
Kinetics of Oral Dosing
... Review the factors influencing the drug accumulation or disappearance rate in the body after the oral administration Appreciate the relative changes in the absorption and elimination rates after oral administration Know the major kinetic parameters that can be calculated from the oral data Know the ...
... Review the factors influencing the drug accumulation or disappearance rate in the body after the oral administration Appreciate the relative changes in the absorption and elimination rates after oral administration Know the major kinetic parameters that can be calculated from the oral data Know the ...
Macrolide Antibiotics - Christchurch Drug Information Service
... daily administration, either orally or intravenously, with similar efficacy. Dilution in 250mL of either normal saline or 5% dextrose, administered over 60 minutes into a large proximal vein is required to reduce phlebitis. In severe renal dysfunction (CrCl<0.5mL/s) the dose should be halved. Azithr ...
... daily administration, either orally or intravenously, with similar efficacy. Dilution in 250mL of either normal saline or 5% dextrose, administered over 60 minutes into a large proximal vein is required to reduce phlebitis. In severe renal dysfunction (CrCl<0.5mL/s) the dose should be halved. Azithr ...
entocort ec - PI
... even fatal course in susceptible patients or patients on immunosuppressant doses of glucocorticosteroids. In patients who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route and duration of glucocorticosteroid administration affect the risk of developi ...
... even fatal course in susceptible patients or patients on immunosuppressant doses of glucocorticosteroids. In patients who have not had these diseases, particular care should be taken to avoid exposure. How the dose, route and duration of glucocorticosteroid administration affect the risk of developi ...
Tykerb - Novartis Pharmaceuticals Corporation
... TYKERB can cause fetal harm when administered to a pregnant woman. Based on findings in animals, TYKERB is expected to result in adverse reproductive effects. Lapatinib administered to rats during organogenesis and through lactation led to death of offspring within the first 4 days after birth [see ...
... TYKERB can cause fetal harm when administered to a pregnant woman. Based on findings in animals, TYKERB is expected to result in adverse reproductive effects. Lapatinib administered to rats during organogenesis and through lactation led to death of offspring within the first 4 days after birth [see ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.